A5086207620- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- RNA modifications and cancer
- Anesthesia and Neurotoxicity Research
- Mycobacterium research and diagnosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- MicroRNA in disease regulation
- Medical Imaging and Pathology Studies
- Pulmonary Hypertension Research and Treatments
- Ideological and Political Education
- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Research Studies
- Geology and Paleoclimatology Research
- Technology-Enhanced Education Studies
- Intensive Care Unit Cognitive Disorders
- Immune Cell Function and Interaction
- Enhanced Recovery After Surgery
- Innovative Teaching Methods
- Hydrocarbon exploration and reservoir analysis
- Immunotherapy and Immune Responses
- Ferroptosis and cancer prognosis
- Lung Cancer Treatments and Mutations
- Acute Ischemic Stroke Management
- Innovative Educational Techniques
- Advanced Battery Materials and Technologies
Nanjing Drum Tower Hospital
2023-2025
Nanjing Medical University
2023-2025
Jiangsu Hengrui Medicine (China)
2024
Weatherford College
2023
Nantong University
2021-2022
Affiliated Hospital of Nantong University
2022
China University of Petroleum, Beijing
2019
Qingdao University
2019
This study aimed to investigate the causal relationship between mitochondrial biological function and lung cancer, including its subtypes, via MR. SNPs significantly associated with cancer subtypes were employed as instrumental variables. MR-Egger regression, simple mode, weighted median, utilized determine exposure factor occurrence of subtypes. NADH dehydrogenase (ubiquinone) flavoprotein 2 transmembrane protein 70 found have a adenocarcinoma, acting protective factors. The import inner...
The incidence and mortality rates of trachea, bronchus, lung cancers (TBL) continue to rise globally. Despite a trend increasing cases among younger populations, the majority patients with TBL remain concentrated in 50 + age group. A comprehensive analysis data from Global Burden Disease (GBD) database reveals that fruit-deficient diets significantly contribute both disability-adjusted life years (DALYs) associated TBL, particularly aged 55 older, thus posing major global health challenge....
Abstract Background Biochemistry is a core subject in clinical medical education. The traditional classroom teaching model led by teachers often limited to the knowledge transfer of and passive acceptance students. It lacks interactive efficient methods not enough meet learning needs educational goals modern combination WeChat public platform, flipped TBL closer real life workplace, helping students cultivate comprehensive literacy ability solve practical problems. At same time, this has yet...
BackgroundPlatinum-doublet chemotherapy plus immunotherapy has been the standard of care for first-line treatment advanced non-small cell lung cancer lacking actional driver mutations. However, optimization drug combinations is still needed to find a better balance between therapeutic efficacy and safety in era. We aimed investigate platinum-free albumin bound paclitaxel (nab-paclitaxel) combined with camrelizumab apatinib as patients adenocarcinoma.MethodsIn this multicenter open-label,...
Abstract Objective To investigate the effect of a bilateral paravertebral block (PVB) on cognitive function in elderly patients undergoing radical gastrectomy for gastric cancer. Methods Sixty (40 men and 20 women) aged 65–80 surgery under general anaesthesia were included randomly assigned to either PVB group or control group. Patients had before incision single-shot ultrasound-guided at T8 level with mL ropivacaine 0.375%, while no block. both groups BIS-guided total intravenous propofol...
With WeChat platform as the carrier, we explored effect of online and offline mixed teaching mode applied to Biochemistry teaching. One hundred eighty-three students from 4-year nursing major Xinglin College Nantong University in 2018 2019 were used observation group, using hybrid methods, 221 majoring 2016 2017 control where traditional classroom method was adopted. The usual stage scores final group significantly higher than those (P < .01). micro-lecture videos, animations, periodic...
Objective: To construct a competitive endogenous RNA (ceRNA) regulatory network derived from exosomes of human breast cancer (BC) by using the exoRbase database, to explore possible pathogenesis BC, and develop new targets for future diagnosis treatment. Methods: The exosomal gene sequencing data BC patients normal controls were downloaded expression profiles mRNA, long non-coding (lncRNA), circular (circRNA) analyzed R language. Use Targetscan miRanda database jointly predict differentially...
Objective The aim of this study was to identify potential causal cytokines in thymic malignancies and benign tumors from the FinnGen database using Mendelian randomization (MR). Methods In study, data genome-wide association studies (GWAS) 91 were used as exposure factors, those malignant outcome variables. Two methods determine relationship between factors variables: inverse variance weighting (IVW) MR-Egger regression. Sensitivity analysis performed three methods, namely, heterogeneity...
Lung cancer, on a global scale, leads to the most common cases of cancer mortalities. Novel therapeutic approaches are urgently needed disrupt this lethal disease. The rapid development tumor immunology combining breakthroughs involving fatty acid metabolism brings possibilities. Directing is supposed help discover potential prognostic biomarkers and treatment targets for lung cancer.
This research employed Mendelian randomization (MR) methods to explore whether metabolites are causally associated with embolic stroke of undetermined source (ESUS).
Abstract A competing endogenous RNA (ceRNA) regulatory network in the blood exosomes of small cell lung cancer (SCLC) patients was constructed by bioinformatics methods to explore pathogenesis. Blood exosomal gene sequencing data SCLC and normal controls were downloaded from exorbase 2.0 database, expression profiles mRNAs, long non-coding RNAs (lncRNAs), circular (circRNAs) differentially analyzed using R language, miRNAs binding expressed lncRNAs predicted miRcode circRNAs Starbase...
Abstract Objective To investigate the effect of bilateral paravertebral nerve block on cognitive function in elderly patients undergoing radical gastrectomy for gastric cancer(GC). Methods One sixty patients, which were 40 males and 20 females, aged 65-80 years old, GC surgery under general anesthesia The First People’s Hospital Taicang from January 2019 to December 2021 included randomly divided into control group (group C) PVB).Group PVB received ultrasound-guided blocks T8 with 0.375%...
Among the most lethal cancers, pancreatic adenocarcinoma (PAAD) is an essential component of digestive system malignancies that still lacks effective diagnosis and treatment methods. As exosomes competing endogenous RNA (ceRNA) regulatory networks in tumors go deeper, we expect to construct a ceRNA network derived from blood PAAD patients by bioinformatics methods develop survival prediction model based on it.Blood exosome sequencing data normal controls were downloaded exoRbase database,...