A5031872000- Urological Disorders and Treatments
- Genital Health and Disease
- Sexual function and dysfunction studies
- Renal cell carcinoma treatment
- Renal and Vascular Pathologies
- Sexual Differentiation and Disorders
- Bladder and Urothelial Cancer Treatments
- Heavy Metal Exposure and Toxicity
- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
- Pediatric Urology and Nephrology Studies
- Hormonal and reproductive studies
- Reconstructive Surgery and Microvascular Techniques
- Hormonal Regulation and Hypertension
- Reproductive tract infections research
- Trace Elements in Health
- Renal Diseases and Glomerulopathies
- Urinary and Genital Oncology Studies
- Sexuality, Behavior, and Technology
- Prostate Cancer Treatment and Research
- Urinary Bladder and Prostate Research
- Glycosylation and Glycoproteins Research
- Urinary Tract Infections Management
- Veterinary Medicine and Surgery
- Psychoanalysis and Psychopathology Research
Medical University of Białystok
2006-2022
Weatherford College
2020
Jagiellonian University
2014
Centralny Szpital Kliniczny
2007
Asklepios Klinik Altona
1982
Phenomena associated with changes in cell membranes are thought to play an important role the cancer transformation. We hypothesized that electrical charge of tumor cells can indirectly represent membrane-based have occurred during transformation and may indicate status. Here, we describe work showing phospholipids, proteins content, electric charge, all altered pT2 stage/grade G3 bladder cancer. Qualitative quantitative phospholipid composition presence integral membrane were identified...
Many epidemiological and experimental studies report a strong role of chemical carcinogens in the etiology bladder cancer. However, involvement trace elements tumorigenesis transitional cell carcinoma has been poorly investigated. The aim this study was to examine relationship between zinc, copper cancer.Zinc concentration Cu/Zn ratio two 36-sample series cancer tissue sera from patients with neoplasm were matched those control group. amount every sample determined using atomic absorption...
Phospholipids are ubiquitous in nature and essential for the lipid bilayer of cell membranes. Their structural functional properties pivotal survival cell. In this study phospholipids healthy cancerous human renal tissues from same patients compared with special reference to electric charge membrane. A simple highly effective normal-phase method is described analyzing content. This work focused on changes content (PtdIns, phosphatidylinositol; PtdSer, phosphatidylserine; PtdEtn,...
Objective. To investigate the relationship between lead and bladder cancer. Material methods. The levels of concentration in blood cancer tissue from a sample set 36 patients were measured then compared with those normal group. obtained evaluated depending on stage tumour. level each was determined by atomic absorption spectrometry. Results. reached statistically higher values both this carcinoma control No neoplasm tumour demonstrated. Conclusion. results suggest that there is exposure to...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Nov 2001ULTRASTRUCTURE OF THE TUNICA ALBUGINEA IN CONGENITAL PENILE CURVATURE BARBARA DAREWICZ, JACEK KUDELSKI, BEATA SZYNAKA, HENRYK F. NOWAK, and JANUSZ DAREWICZ DAREWICZBARBARA , KUDELSKIJACEK KUDELSKI SZYNAKABEATA SZYNAKA NOWAKHENRYK NOWAK DAREWICZJANUSZ View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)65671-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
Abstract Background: Human urinary bladder cancer is one of the most common cancers worldwide with mortality rate approximately 165,000 people annually. The modulation extracellular matrix a crucial event in metastatic spread, among others angiogenesis. It initiated and prolonged by cascade metalloproteinases. MMP-14 MMP-15 are associated high degree malignancy, aggressiveness, survival prognosis activation other metalloproteinases (MMPs). This study was aimed at evaluating expression...
Cancer development is connected with improper glycosylation of proteins. There are alterations in synthesis and expression sugar structures. These changes can be important not only at early steps tumor but also next stages cancer invasiveness its ability to form metastases. Oligosaccharide structures glycans tumors deviate from normal cells. Particularly relatively increased degrees branching sialylation N-glycans, enhanced presentation short-chain mucin-type O-glycans the blood group ABO...
Abstract The aim of this study was to determine serum levels selenium (Se) in patients with larynx and urinary system cancers. We also estimated the influence dietary habits on Se status examined patients. mean content cancer (48.94 ± 16.3 μ/l) (51.00 18.6 lower than control group (68.25 15.6 μg/l; P = 0.000006 or 64.03 16.8 0.0112, respectively). In tissue only, level kidney (75.37 40.3 μg/l) compare dead body (220.68 83.6 μg/l). have observed correlation between (r 0.297; 0.002). Patients...
The aim of this study was to examine the relationship between cadmium (Cd) and bladder cancer (urothelial carcinoma bladder). Cadmium concentrations in two 36-sample series tissue blood, from patients with neoplasm, were matched those control group. amount heavy metal every sample determined using atomic absorption spectrometry. This correlated tumour stage. While median concentration levels reached statistically lower values tissue, as compared non-cancer one (11.695 ng/g 56.32...
Cancer cells are characterized by an aberrant increase in protein N-glycosylation and disruption of E-cadherin-mediated adherens junctions. However, the relationship between alterations process loss E-cadherin adhesion cancer remains unclear. The mechanisms altered expression adhesive glycoproteins have not been fully elucidated. Thus, aim this study was to examine sialyl Lewisa/x, NeuAcα2-3Gal, NeuAcα2-6Gal/GalNAc structures normal renal tissue intermediate cancerous tissues from patients...
Human urinary bladder cancer is a huge worldwide oncological problem causing many deaths every year. The degradation of extracellular matrix (ECM) induced by molecules such as metalloproteinases (MMPs) one the main factors influencing process metastasis origination. MMP expression tied to tumor aggressiveness, stage, and patient prognosis. cleavage constituent proteins initiated prolonged metalloproteinases, MMP-3 MMP-10. aim this study was evaluate activity both MMPs in human occurring at...
A 29-year-old mentally ill farmer underwent microsurgery for the resuturing of penis and testicles which he himself had chopped off with an ax. Microsurgery urethra, corpora cavernosa, arteries veins was begun 10 h after trauma. The veins, were anastomosed covered a free flap scrotum skin. Three weeks surgery, tested showed good healing. However, in 65% penis, necrosis occurred.
Many epidemiological and experimental studies report a strong role of chemical carcinogens in the etiology bladder cancer. However, involvement heavy metals tumourigenesis urothelial carcinoma has been poorly investigated. Therefore, aim this study was to examine relationship between chromium (Cr) cancer.Chromium concentration two 36-sample series cancer tissue sera from patients with neoplasm were matched those control group. The amount trace elements every sample determined using atomic...
Collagenases are enzymes starting collagen degradation. The role of collagenases in renal carcinoma development is not well understood.Evaluation content and collagenase expression activity human kidney cancers.Collagen was measured by the hydroxyproline assay. were evaluated Western blotting ELISA. Fluorogenic substrate used to measure enzyme activity.Collagen significantly decreases with progression cancer. Both first present high molecular complexes both control cancer tissue. healthy...