- Schizophrenia research and treatment
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Eating Disorders and Behaviors
- Regulation of Appetite and Obesity
- Psychoanalysis and Psychopathology Research
- Mental Health and Psychiatry
- Child Nutrition and Feeding Issues
- Electroconvulsive Therapy Studies
- Pain Management and Placebo Effect
- Health, Medicine and Society
- Biochemical Analysis and Sensing Techniques
- Obsessive-Compulsive Spectrum Disorders
- Mental Health Treatment and Access
- Health Systems, Economic Evaluations, Quality of Life
- Adipose Tissue and Metabolism
- Adolescent and Pediatric Healthcare
- Neurotransmitter Receptor Influence on Behavior
- Psychosomatic Disorders and Their Treatments
- Body Image and Dysmorphia Studies
- Psychotherapy Techniques and Applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Child and Adolescent Psychosocial and Emotional Development
- Healthcare Systems and Practices
- Circadian rhythm and melatonin
Université Paris Cité
2011-2024
Centre Hospitalier Sainte-Anne
2009-2024
Sorbonne Paris Cité
2022
Délégation Paris 5
1999-2021
Inserm
2002-2021
Institut de Psychiatrie et Neurosciences de Paris
2010-2021
FHU Neurovasc
2020
McGill University
2020
Université de Montréal
2016
Sorbonne Université
2013
Ghrelin, a 28-amino acid octanoylated peptide, has recently been identified in rat stomach as an endogenous ligand for the GH secretagogue receptor. In addition to GH-releasing properties, exogenous ghrelin injections exert orexigenic effects both rodents and humans. As peptide appears directly related feeding behavior, we assessed its plasma levels anorexia nervosa (AN) patients before after renutrition constitutionally thin subjects with body mass indexes (BMIs) equivalent those of AN...
Extracellular acyl-coenzyme A binding protein [ACBP encoded by diazepam inhibitor (DBI)] is a phylogenetically ancient appetite stimulator that secreted in nonconventional, autophagy-dependent fashion. Here, we show low ACBP/DBI plasma concentrations are associated with poor prognosis patients anorexia nervosa, frequent and often intractable eating disorder. In mice, induced chronic restraint stress (CRS) accompanied reduction circulating concentrations. We engineered chemical-genetic system...
To estimate the prevalence rates of depression and anxiety in patients with wet age-related macular degeneration (AMD) relationship visual acuity to develop a simple algorithm for screening.This cross-sectional, prospective, observational, multicenter study was performed France, Germany, Italy. Retina specialists at 10 centers per country each enrolled 12 consecutive ARMD. Patients were stratified into four severity groups by using best eye (BE) worst (WE) (VA) thresholds (BE:VA 20/40 WE:VA...
The objective of the present study was to identify factors associated with suicidal behaviors among patients eating disorders.A large database including sociodemographic and clinical characteristics 1,009 consecutive hospitalized for an disorder in Paris, France, examined. Data gathered upon admission hospital were analyzed a history suicide attempt or current ideation, whole sample as well each subtype disorder.Among sample, factor most strongly ideation diagnostic category, highest odds...
Dropout rates from inpatient treatment for eating disorders are very high and have a negative impact on outcome. The purpose of this study was to identify personality factors predictive dropout hospitalization. A total 64 adult patients with anorexia nervosa consecutively hospitalized in specialized unit were included; 19 dropped out. group the completer compared demographic variables, clinical features, dimensions, disorders. There no link between features dropout, among only age associated...
To test the hypothesis that pathological gamblers in French general population who play games available cafés score lower on sensation seeking than regular and nongamblers, Zuckerman's Sensation Seeking Scale was administered to 57 diagnosed gamblers, 40 a control group of 97 nongamblers. Whereas did not obtain significantly mean nongamblers groups, analysis indicated those seek different multiple forms reduce boredom, but they do necessarily excitement-generating activities. One possible...
Contexte: Le concept de mécanisme défense (MD) remonte aux fondements la psychanalyse et en constitue un des piliers théoriques. Plus récemment, raison l'introduction cette notion dans une rubrique expérimentale classifications catégorielles, les MD sont devenus nouveau champ à explorer le domaine recherche communication scientifique. L'augmentation du nombre d'études prenant compte est allée pair avec l'élaboration d'échelles d'évaluation clinique plus utilisables que tests projectifs. Il...