A5101803601- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Cancer-related Molecular Pathways
- Traditional Chinese Medicine Analysis
- Neurological Disease Mechanisms and Treatments
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
- Hormonal Regulation and Hypertension
- Cancer-related molecular mechanisms research
- Sodium Intake and Health
- MicroRNA in disease regulation
- Environmental and Agricultural Sciences
- Pathogenesis and Treatment of Hiccups
- Endometrial and Cervical Cancer Treatments
- Cancer Cells and Metastasis
- Digestive system and related health
- Metabolomics and Mass Spectrometry Studies
- Hemostasis and retained surgical items
- Cancer Risks and Factors
- Lipid metabolism and disorders
- Chromatin Remodeling and Cancer
- Circular RNAs in diseases
- Inflammatory Biomarkers in Disease Prognosis
- Alcohol Consumption and Health Effects
- Inflammatory Bowel Disease
Liaoning Meteorological Bureau
2024
Chinese PLA General Hospital
2024
The University of Melbourne
2023
China Medical University
2022
Southern Medical University
2021
Nanfang Hospital
2021
Affiliated Hospital of Guizhou Medical University
2019-2021
Weatherford College
2021
Guiyang Medical University
2021
Guizhou Cancer Hospital
2019-2021
Objective: Ras-related C3 botulinum toxin substrate1(Rac1) and epithelial mesenchymal transition (EMT) are key therapeutic targets in cancer.We investigated the clinical significance of Rac1 markers EMT expression non-small cell lung cancer (NSCLC), their possible correlation with phenotype.Methods: Immunohistochemistry was used to assess Rac1, Snail1, Twist1, N-cadherin (N-cad), Vimentin (Vim), E-cadherin (E-cad) 153 NSCLC paraffin-embedded specimens 45 normal adjacent tumors.The...
Tumor suppressor p53 is a master regulator of apoptosis and plays key roles in cell cycle checkpoints. responds to metabolic changes alters metabolism through several mechanisms cancer. Lactate dehydrogenase A (LDHA), enzyme glycolysis, highly expressed variety tumors catalyzes pyruvate lactate. In the present study, we first analyzed association clinical significance LDHA breast cancer expressing wild-type (wt-p53) found that mRNA levels are negatively correlated with wt-p53 but not...
Introduction. Stage IIB cervical cancer (CC) is an advanced stage CC with poor prognosis. Inflammatory response plays a crucial role in the development of CC, and systemic inflammatory indexes were related to prognosis several cancers. The objective study was determine prognostic value platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), basophil-to-lymphocyte (BLR), inflammation index (SIRI) as patients CC. Materials Methods. A retrospective...
Breast cancer, the second most common cancer worldwide, is leading cause of cancer-associated mortality in women, accounting for ~15% all mortalities women. The development, local invasion and metastasis breast are associated with dysregulation mutation numerous genes epigenetic mechanisms, including coding RNA non‑coding RNA, such as microRNAs (miRs/miRNAs). Previous studies have shown a dual‑faced role miR‑125b cancer. In present study, total 221 paraffin‑embedded 49 non‑cancerous tissue...
Breast cancer has become the leading cause of cancer-related death among women. A large number patients resistant to drug chemotherapy. Paclitaxel (Taxol) is an effective chemotherapeutic agent used treat patients. Taxol been widely in human malignancies including breast because it can stabilize microtubules resulting cell by causing arrest during G2/M phase cycle. Pro-apoptotic Bcl-2 antagonist killer 1 (Bak) plays important role Taxol-induced apoptosis cancer. In our present study, we...
To examine the clinical significance of unoperated cervical cancer patients treated with different neoadjuvant chemotherapy (NACT) schemes followed by concurrent and radiotherapy (CCRT).This retrospective analysis included women locally advanced NACT-CCRT between September 2011 2014. Neoadjuvant paclitaxel plus cisplatin (TP group; 62 patients) or loplatin (TL 58 patients), which were administered three weekly, loplatin, weekly for synchronous chemotherapy. External beam radiation therapy...
Abstract Abdominal massage (AM), a traditional Chinese medicine-based treatment method, has received considerable attention in the recent years. The aim of present study was to investigate effect AM on high-fat diet (HFD)-induced insulin resistance (IR) comparison with resveratrol (RSV) treatment. Forty-eight male Sprague-Dawley rats were randomly divided into following four groups: standard chow (control group), (model HFD + abdominal (AM and (RSV group). A rat model IR established by...
There is a high need for covered esophageal stents as part of the palliative treatment patients suffering from obstruction, common symptom cancer. This paper describes development soft and flexible multi-functional bilayer membrane carrying paclitaxel, use solution-casting electrospinning to form this material into an stent coating. FDA-approved materials established methods were used shorten certification process. A protective layer consisting polycaprolactone casting film...
Gastric ulcer (GU) is a clinically common disease of the digestive system that adversely affects patients' quality life and work ability. Although some articles have reported acupuncture can improve clinical symptoms GU, efficacy has not been scientifically or methodically evaluated. This study aimed to evaluate effectiveness safety for treatment patients with gastric ulcers.The following electronic databases will be searched from respective dates database inception March 23, 2021: The...
Objective: This study aimed to evaluate methotrexate efficacy in patients with Crohn's disease (CD) and ulcerative colitis (UC), identify predictors of surgery for who were initially treated monotherapy. Design: We performed a retrospective analysis 34,860 inflammatory bowel (IBD) the IBD Bioresource (United Kingdom) prior 9 November 2021. Logistic regression was used factors associated efficacy. The data randomly stratified into training testing sets (7:3). Nomograms developed based on Cox...
Abstract Background: This study evaluated the efficacy and safety of docetaxel combined with lobaplatin, relative to gemcitabine, for treating patients recurrent metastatic breast cancer (rMBC). Methods: Patients rMBC received ≥2 cycles (21 days each) either lobaplatin (DL; n = 21), or gemcitabine (DG; 22). On day 1 each cycle, all were given 75 mg/m 2 intravenous docetaxel. in DL DG also given, respectively, 35 (day 2) 1000 (days 1, 8). Results: Five (11.6%) 16 (37.2%) achieved complete...
Post-stroke depression (PSD) is the most common mental health issue, affecting approximately 33% of stroke survivors. Tuina and acupuncture treatments are often combined to treat PSD; however, there has been no meta-analysis on their synergistic effect. Therefore, we aimed perform a systematic review estimate effectiveness in PSD treatment.The following electronic databases will be searched: PubMed, Cochrane Library, Embase, Web Science, Medline, CNKI, Chinese Biomedical Literature Database,...
MiRNAs can function as oncogenes or tumor suppressor genes. The abnormal expression of miRNAs leads to malignant phenotypes, such cell proliferation, apoptosis, invasion and metastasis, through which it is involved in the process initiation, progression transcriptional regulation network. Therefore, important clarify mechanism miRNA initiation progression. MiRNA includes one-to-many many-to-one between TFto- miRNA-to-target gene, increases complexity regulation, thus affecting biological...
Abstract Drought is more frequent and intensified due to global warming. Changed conditions in Beijing‐Tianjin–Hebei region which drier warmer than before, make it necessary investigate various optimized irrigation schemes the winter wheat production. In this study, DSSAT–CERES‐Wheat model verified by field experimental data was applied simulate yield of Beijing–Tianjin–Hebei from 2010 2069a under RCP8.5 climate scenario. The were set up adjusting amount structure evaluate their adaptive...
e21013 Background: Lung cancer (LC) is the second leading causes of cancer-related mortality and composed diverse molecular types. Tumor suppressor gene TP53 one most frequency mutation genes in cancer, however, whether there are hot sports mutations has always been a challenging issue. The aim this study was to explore spectrums spots LC. Methods: total 1932 LC tissue samples (from same number patients，all cases had patients' informed consent) formalin fixed paraffin embedded were collected...
Diabetic peripheral neuropathy (DPN) is one of the most common microvascular complications diabetes mellitus, with an incidence ranging from 60% to 90%. With change in modern dietary structure, increasing year by year, and DPN also on rise. Acupuncture Tuina treatments are often combined treat DPN; however, there has been no meta-analysis their synergistic effect; therefore, we aimed perform a systematic review estimate effectiveness acupuncture treatment.Nine electronic databases were...