A5011628549- Neurobiology and Insect Physiology Research
- Olfactory and Sensory Function Studies
- Neural dynamics and brain function
- Genetic Associations and Epidemiology
- Neuroscience and Neuropharmacology Research
- Bioinformatics and Genomic Networks
- Functional Brain Connectivity Studies
- Photoreceptor and optogenetics research
- Fusion and Plasma Physics Studies
- bioluminescence and chemiluminescence research
- Neuroinflammation and Neurodegeneration Mechanisms
- Genetic Mapping and Diversity in Plants and Animals
- Biochemical Analysis and Sensing Techniques
- Memory and Neural Mechanisms
- Circadian rhythm and melatonin
- Epigenetics and DNA Methylation
- Neural Networks and Applications
- Genetic and phenotypic traits in livestock
- Neurotransmitter Receptor Influence on Behavior
- Genetics and Neurodevelopmental Disorders
- Neuroscience and Neural Engineering
- Animal Genetics and Reproduction
University of California, San Diego
2023-2024
Miami University
2018
Jackson Laboratory
2018
University of Miami
2018
California Institute of Technology
2017
Understanding the computations that take place in brain circuits requires identifying how neurons those are connected to one another. We describe a technique called TRACT (TRAnsneuronal Control of Transcription) based on ligand-induced intramembrane proteolysis reveal monosynaptic connections arising from genetically labeled interest. In this strategy, expressing an artificial ligand (‘donor’ neurons) bind and activate genetically-engineered receptor their synaptic partners (‘receiver’...
Animals exhibit innate behaviors that are stereotyped responses to specific evolutionarily relevant stimuli in the absence of prior learning or experience. These can be reduced an axis valence, whereby odors evoke approach avoidance responses. The posterolateral cortical amygdala (plCoA) mediates attraction and aversion odor. However, little is known about how this brain area gives rise opposing motivational valence. Here, we sought define circuit features plCoA give We characterized...
Animals exhibit innate behaviors that are stereotyped responses to specific evolutionarily relevant stimuli in the absence of prior learning or experience. These can be reduced an axis valence, whereby odors evoke approach avoidance responses. The posterolateral cortical amygdala (plCoA) mediates attraction and aversion odor. However, little is known about how this brain area gives rise opposing motivational valence. Here, we sought define circuit features plCoA give We characterized...
The ways in which sensory stimuli acquire motivational valence through association with other is one of the simplest forms learning. Though we have identified many brain nuclei that play various roles reward processing, a significant gap remains understanding how value encoding transforms layers processing. To address this gap, carried out comparative investigation olfactory tubercle (OT), and ventral pallidum (VP) - 2 connected basal ganglia both been implicated First, using anterograde...
The ways in which sensory stimuli acquire motivational valence through association with other is one of the simplest forms learning. Although we have identified many brain nuclei that play various roles reward processing, a significant gap remains understanding how encoding transforms layers processing. To address this gap, carried out comparative investigation mouse anteromedial olfactory tubercle (OT), and ventral pallidum (VP) - 2 connected basal ganglia both been implicated First, using...
The ways in which sensory stimuli acquire motivational valence through association with other is one of the simplest forms learning. Although we have identified many brain nuclei that play various roles reward processing, a significant gap remains understanding how encoding transforms layers processing. To address this gap, carried out comparative investigation mouse anteromedial olfactory tubercle (OT), and ventral pallidum (VP) - 2 connected basal ganglia both been implicated First, using...
The ways in which sensory stimuli acquire motivational valence through association with other is one of the simplest forms learning. Though we have identified many brain nuclei that play various roles reward processing, a significant gap remains understanding how encoding transforms layers processing. To address this gap, carried out comparative investigation olfactory tubercle (OT), and ventral pallidum (VP) - 2 connected basal ganglia both been implicated First, using anterograde...
Abstract Animals exhibit innate behaviors that are stereotyped responses to specific evolutionarily relevant stimuli in the absence of prior learning or experience. These can be reduced an axis valence, whereby odors evoke approach avoidance responses. The posterolateral cortical amygdala (plCoA) mediates attraction and aversion odor. However, little is known about how this brain area gives rise opposing motivational valence. Here, we sought define circuit features plCoA give We...
The ways in which sensory stimuli acquire motivational valence through association with other is one of the simplest forms learning. Though we have identified many brain nuclei that play various roles reward processing, a significant gap remains understanding how encoding transforms layers processing. To address this gap, carried out comparative investigation anteromedial olfactory tubercle (OT), and ventral pallidum (VP) - 2 connected basal ganglia both been implicated First, using...
Animals have evolved innate responses to cues including social, food, and predator odors. In the natural environment, animals are faced with choices that involve balancing risk reward where significance may be at odds internal need. The ability update value of a cue through learning is essential for navigating changing uncertain environments. However, mechanisms involved in this modulation not well defined mammals. We established new olfactory assay challenges thirsty mouse choose an...
ABSTRACT Genetic signal detection in genome-wide association studies (GWAS) is enhanced by pooling small signals from multiple Single Nucleotide Polymorphism (SNP), e.g. across genes and pathways. Because are believed to influence traits via gene expression, it of interest combine information expression Quantitative Trait Loci (eQTLs) a or the same pathway. Such methods, widely referred as transcriptomic wide analysis (TWAS), already exist for analysis. Due possibility eliminating most...
The ways in which sensory stimuli acquire motivational valence through association with other is one of the simplest forms learning. Though we have identified many brain nuclei that play various roles reward processing, a significant gap remains understanding how encoding transforms layers processing. To address this gap, carried out comparative investigation anteromedial olfactory tubercle (OT), and ventral pallidum (VP) - 2 connected basal ganglia both been implicated First, using...