A5069841144- Photochemistry and Electron Transfer Studies
- Electron Spin Resonance Studies
- Radical Photochemical Reactions
- Nanocomposite Films for Food Packaging
- Bioactive Compounds and Antitumor Agents
- Electrochemical Analysis and Applications
- Thyroid Disorders and Treatments
- Erythrocyte Function and Pathophysiology
- Synthesis and biological activity
- Molecular Sensors and Ion Detection
- Synthesis and Biological Evaluation
- Immune Response and Inflammation
- Studies on Chitinases and Chitosanases
- Phagocytosis and Immune Regulation
- Mitochondrial Function and Pathology
- Digital Imaging for Blood Diseases
- Crystal structures of chemical compounds
- Antimicrobial agents and applications
- High Altitude and Hypoxia
- Synthesis and Characterization of Heterocyclic Compounds
- Nuclear Receptors and Signaling
- Multicomponent Synthesis of Heterocycles
- Artificial Intelligence in Healthcare
- Light effects on plants
- Free Radicals and Antioxidants
Instituto de Investigaciones Biomédicas Sols-Morreale
2016-2024
Consejo Superior de Investigaciones Científicas
2016-2024
Universidad Autónoma de Madrid
1988-2024
Universitat Autònoma de Barcelona
2024
Vall d'Hebron Institut de Recerca
2024
Hospital Universitario 12 De Octubre
2022
Universidad Complutense de Madrid
2003-2018
Universidad de Las Palmas de Gran Canaria
2016
Instituto de Biomedicina y Biotecnología de Cantabria
2016
Chitin and its deacetylated derivative, chitosan, are natural polymers that have been proposed to be used in a wide range of applications. Due their origin, both chitin chitosan cannot defined as unique chemical structure but family which present high variability physical properties. This is related not only the origin samples also method preparation. this variability, success polymer on each application depends properties polymer. In previous review, we highlighted relationship between...
The methods to obtain chitooligosaccharides are tightly related the physicochemical properties of end products. Knowledge these characteristics is crucial describing biological functions chitooligosaccharides. Chitooligosaccharides were prepared either in a single-step enzymatic hydrolysis using chitosanase, or two-step chemical-enzymatic hydrolysis. hydrolyzed products obtained preparation composed mainly 42% fully deacetylated oligomers plus 54% monoacetylated oligomers, and they...
Map3k8 (Cot/Tpl2) activates the MKK1/2-ERK1/2, MAPK pathway downstream from interleukin-1R, tumor necrosis factor-αR, NOD-2R (nucleotide-binding oligomerization domain-like 2R), adiponectinR, and Toll-like receptors. plays a key role in innate adaptive immunity influences inflammatory processes by modulating functions of different cell types. However, its atherogenesis remains unknown. In this study, we analyzed kinase pathology.We show here that deficiency results smaller numbers...
The modulation of the host’s metabolism to protect tissue from damage induces tolerance infections increasing survival. Here, we examined role thyroid hormones, key metabolic regulators, in outcome malaria. Hypothyroidism confers protection experimental cerebral malaria by a disease mechanism. Hypothyroid mice display increased survival after infection with Plasmodium berghei ANKA, diminishing intracranial pressure and brain damage, without altering pathogen burden, blood-brain barrier...
Twelve naphthazarin derivatives were reduced electrochemically giving rise to the corresponding semiquinone anion radicals. Their e.s.r. spectra recorded in situ and their hyperfine coupling constants g factor evaluated. For this purpose, SCF INDO MO calculations performed order obtain an approximate value of different constants. The structure these radicals was also deduced from calculations, showing a strong linear O–H–O hydrogen bond, free rotation methyl group, absence interactions methoxy-group.
Abstract Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, deficiency strongly impairs increase in circulating mature (Ly6G high CD11b + ) and immature low neutrophils. After chimaeric bone marrow (BM) transplantation into recipient −/− mice, lipopolysaccharide did not Ly6G cells decreased cells. Lipopolysaccharide-treated mice showed production granulocyte colony-stimulating...
Hypothyroidism is often associated with anemia and immunological disorders. Similar defects are found in patients mice a mutated dominant-negative thyroid hormone receptor α (TRα) knockout devoid of this receptor, suggesting that isoform responsible for the effects hormones hematopoiesis. However, hematological phenotype lacking also TRβ has not yet been examined. We show here TRα1/TRβ -knockout female mice, all known receptors capacity to bind hormones, do have overt contrast hypothyroid...
Abstract Bone marrow erythropoiesis is mainly homeostatic and a demand of oxygen in tissues activates stress the spleen . Here, we show an increase number circulating erythrocytes apolipoprotein E −/− mice fed Western high-fat diet, with similar leukocytes CD41 + events (platelets). Atherogenic conditions no variations this cell lineage bone marrow. Spleens from atherogenic augmented late-stage erythroblasts biased differentiation progenitor cells towards erythroid lineage, CD71 CD41CD34 −...
A mechanism for glucose degradation in alkaline media has been proposed based upon ESR spectroscopy studies. This degradative process carried out with aqueous Bu4NOH dimethyl sulphoxide (DMSO) at room temperature. Several radicals semidione-like structures are generated during this process, the presence of an α-hydroxycarbonyl group molecule being a crucial requisite formation such radicals. Cleavage C(3)–C(4) bond, due to base catalysed retroaldolization is first step degradation. The...
Article Charge Transfer Complexes between Several Chloronaphthazarin Derivatives and Triethanolamine was published on February 1, 1982 in the journal Zeitschrift für Physikalische Chemie (volume 131, issue 2).
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemical reduction of 2-(arylideneamino)furans: an unexpected stable anion-radicalF. Barba, J. R. Diaz, A. Sanchez, and C. SeoaneCite this: Org. Chem. 1992, 57, 15, 4287–4289Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July 1992https://pubs.acs.org/doi/10.1021/jo00041a041https://doi.org/10.1021/jo00041a041research-articleACS PublicationsRequest reuse permissionsArticle...