Jose Juan Escobar-Barranco
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Heme Oxygenase-1 and Carbon Monoxide
Hospital de Nens de Barcelona
2019-2024
Instituto de Salud Carlos III
2019
PurposeTo compare the efficacy and safety of brolucizumab with aflibercept in patients diabetic macular edema (DME).DesignDouble-masked, 100-week, multicenter, active-controlled, randomized trials.MethodsSubjects were 1:1:1 to 3 mg/6 mg or 2 KESTREL (n = 566) 1:1 6 KITE 360). Brolucizumab groups received 5 loading doses every weeks (q6w) followed by 12-week (q12w) dosing, optional adjustment 8 (q8w) if disease activity was identified at predefined assessment visits; 4 (q4w) fixed q8w dosing....
Aim To explore associations between artificial intelligence (AI)-based fluid compartment quantifications and 12 months visual outcomes in OCT images from a real-world, multicentre, national cohort of naïve neovascular age-related macular degeneration (nAMD) treated eyes. Methods Demographics, acuity (VA), drug number injections data were collected using validated web-based tool. Fluid including intraretinal (IRF), subretinal (SRF) pigment epithelial detachment (PED) the fovea (1 mm),...
Aim To evaluate the impact of fluid volume fluctuations quantified with artificial intelligence in optical coherence tomography scans during maintenance phase and visual outcomes at 12 24 months a real-world, multicentre, national cohort treatment-naïve neovascular age-related macular degeneration (nAMD) eyes. Methods Demographics, acuity (VA) number injections were collected using Fight Retinal Blindness tool. Intraretinal (IRF), subretinal (SRF), pigment epithelial detachment (PED), total...
The aim of this study is to develop guidance on the use intravitreal dexamethasone implants in treatment diabetic macular edema.The was performed using modified Delphi method obtain a consensus among panel experts management patients with edema and clinical practice. Thirty-seven members, retina, from different Spanish centers were invited participate. Individual anonymous opinions asked by answering 76-item questionnaire across 11 topic areas (two rounds done). Level agreement assessed...
Timely anti-vascular endothelial growth factor (VEGF) treatment is crucial for visual function in neovascular age-related macular degeneration (nAMD). The aim of this study was to assess the reasons anti-VEGF delay during COVID-19 lockdown and its clinical impact patients with nAMD.A retrospective, observational, multicentre nAMD treated therapy performed 16 centres nationwide. Data were retrieved from FRB Spain registry, patient medical records administrative databases. Patients divided...
To evaluate the safety and efficacy of BI 1467335 in patients with non-proliferative diabetic retinopathy (NPDR).