A5065896387- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Optical Coherence Tomography Applications
- Corneal surgery and disorders
- Retinal and Macular Surgery
- Retinal Development and Disorders
- Obstructive Sleep Apnea Research
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Ocular and Laser Science Research
- Menopause: Health Impacts and Treatments
- Horticultural and Viticultural Research
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Visual Impairment Studies
- Ophthalmology and Eye Disorders
- Estrogen and related hormone effects
- Agricultural and Food Sciences
- Sleep and Wakefulness Research
- Cerebrovascular and Carotid Artery Diseases
- Growth and nutrition in plants
- Higher Education Teaching and Evaluation
- Neuroscience of respiration and sleep
Hospital Universitario Miguel Servet
2014-2023
Instituto de Investigación Sanitaria Aragón
2015-2023
National Pedagogic University
2022
Universidad de Zaragoza
2012-2021
Instituto Aragonés de Ciencias de la Salud
2014-2020
Toronto Western Hospital
2013
Ophthalmology Associates (United States)
2010-2012
The purpose of this study is evaluate the efficacy and safety medicinal products containing original Age-Related Eye Disease group (AREDS) formulation at doses approved in Europe (EU, control group; n = 59) with a product that adds DHA, lutein, zeaxanthin, resveratrol hydroxytyrosol to formula (intervention 50). This was multicenter, randomized, observer-blinded trial conducted patients aged 50 years or older diagnosed unilateral exudative Age related Macular Degeneration AMD. At month 12,...
To compare choroidal thickness between patients with type 2 diabetes (T2D) and healthy controls measured using swept-source optical coherence tomography (SS-OCT).The sample comprised 157 eyes of 94 T2D patients, 48 which had diabetic macular edema (DME), 71 normal 38 patients. Subfoveal (SF) thickness, at 500-μm intervals up to 2500 μm nasal temporal from the fovea were SS-OCT. Choroidal thicknesses compared groups Student's t-test. Additionally, Pearson correlations calculated duration,...
To determine whether retrobulbar blood flow (RBF) velocities are predictive of conversion to glaucoma.A total 262 glaucoma suspects were prospectively selected. Participants had normal visual field, increased intraocular pressure, and glaucomatous optic disc appearance at baseline. Topographic analysis the nerve head was performed using a confocal laser scanning ophthalmoscope velocity vessels measured by color Doppler imaging. Conversion assessed according changes in color-coded Moorfields...
<h3>Purpose</h3> To evaluate the visual and anatomical outcomes of dexamethasone intravitreal implant (DXI; 700 μg, Ozurdex; Allergan, Irvine, California, USA) as adjunctive therapy for patients with refractory wet age-related macular degeneration (AMD). <h3>Methods</h3> Retrospective review medical records seven (seven eyes) who initially responded well to ranibizumab but subsequently developed persistent intra/sub-retinal fluid (IRF/SRF) underwent a single injection DXI, between May 2012...
To analyze the effects of a dexamethasone intravitreal implant (DEX; Ozurdex 700 μg; Allergan) administered immediately after cataract surgery in diabetic patients.
Purpose.: To evaluate the outcomes of standard automated perimetry (SAP) in patients with obstructive sleep apnea (OSA). Methods.: Eighty OSA and 111 age-matched controls were consecutively prospectively enrolled. One eye per subject was randomly selected. All participants underwent at least one reliable SAP (24-2 SITA Standard algorithm). The peripapillary retinal nerve fiber layer thickness (RNFL) measured spectral-domain optical coherence tomography (OCT). Patients classified into three...
Purpose: To describe the presumed retinal toxicity after using specific batches of perfluorocarbon liquid ALA OCTA (Alamedics, Dornstadt, Germany) in pars plana vitrectomy. Methods: This is an observational retrospective consecutive case series analyses patients operated on vitrectomy for detachment or intraocular lens subluxation, 150141 200114 as assistance during surgery a single center. Patients were included this report if they manifested signs throughout follow-up, such and pigment...
Purpose: To compare the diagnostic performance of different segmentations nerve fiber layer (NFL) thickness measurements using an artificial neural network and to define optimal number sectors with best ability for glaucoma diagnosis. Methods: A total 117 patients 123 normal subjects were included in study. NFL performed Spectralis-OCT (Heidelberg Engineering) obtain average; from 2 semicircles, 4 quadrants, 6, 8, 12, 16, 24, 32, 64 sectors; 768 uniformly divided locations around...
To compare the macular choroidal thinning between young healthy, aged high myopic, and type 2 diabetic (T2D) patients using Early Treatment Diabetic Retinopathy Study (ETDRS) grid three-dimensional (3D) maps.A prospective study including 102 eyes of 51 healthy subjects, 60 30 24 12 myopic patients, 110 55 T2D patients. Choroidal thickness (CT) was examined with swept-source optical coherence tomography Triton DRI (Topcon Corporation, Tokyo, Japan). The choroid automatically segmented...
The effect of obstructive sleep apnea (OSA) syndrome in the peripapillary retinal nerve fiber layer (RNFL) thicknesses remains unclear. purpose this study was to assess RNFL measurements acquired using scanning laser polarimetry (SLP) and optical coherence tomography (OCT) patients with OSA. sample cross-sectional included 40 OSA 45 age-matched controls, consecutively prospectively selected. All participants underwent at least one reliable standard automated perimetry (SAP) test, while were...
To compare the efficacy and safety of a new ocular insert versus conventional mydriasis in cataract surgery.We selected 70 patients undergoing surgery. Thirty five (Group 1) received instillation mydriatic drops (tropicamide 1%, phenylephrine 10%, cyclopentolate 1%) prior to surgery, 35 2) had Mydriasert (Théa Pharma) (0.28 mg tropicamide 5.4 hydrochloride) placed inferior fornix. Pupil size before after blood pressure, heart rate were measured.Before pupil diameter was 9.44 ± 1.17 mm Group...
Purpose . To evaluate anatomical retinal changes measured by spectral-domain optical coherence tomography (SD-OCT), after applying photodynamic therapy (PDT) for treatment of chronic central serous chorioretinopathy (CSC). Methods A retrospective analysis was conducted on 43 patients (48 eyes) with CSC treated PDT. Visual acuity (VA), thickness (CRT), outer nuclear layer (ONL) thickness, subretinal fluid (SRF), and photoreceptor ellipsoid zone (EZ) SD-OCT were collected at baseline 3, 6, 12...
This study was done to evaluate the visual and anatomical outcomes of topical regenerating agents as a novel therapy for neutrophic corneal ulcer (NCU) secondary acanthamoeba infection.A 20-year-old woman with history contact lens wear referred our hospital keratitis after responding poorly conventional treatment. In vivo confocal microscopy images suggested double-walled cysts in anterior stroma. Acanthamoeba infection confirmed by laboratory findings. She started on 0.1 % propamidine 0.02...
Aim: To compare the treatment effect of brolucizumab, a novel anti-vascular endothelial growth factor therapeutic, with putative placebo in patients wet age-related macular degeneration. Materials and Methods: Clinical treatment-effect data from receiving brolucizumab 6 mg HAWK HARRIER studies were compared modelled using previously developed validated indirect response, non-linear, mixed effects model describing natural visual acuity decline The incorporated patient-level sham injection...
<h3>Background/aims</h3> To determine the structure–function relationship between equivalent visual field areas obtained with Octopus perimeter (OP), and peripapillary retinal nerve fibre layer (RNFL) thickness measured spectral-domain optical coherence tomography (OCT) in healthy individuals patients glaucomatous optic neuropathy. <h3>Methods</h3> Eighty-eight normal subjects 150 open-angle glaucoma were prospectively recruited. Eligible participants for group required to have elevated...
Objective . To compare the equivalent optic nerve head (OHN) parameters obtained with confocal scanning laser ophthalmoscopy (HRT3) and spectral-domain optical coherence tomography (OCT) in healthy glaucoma patients. Methods One hundred eighty-two consecutive subjects 156 patients open-angle were divided into 2 groups according to intraocular pressure visual field outcomes. All participants underwent imaging of ONH HRT3 Cirrus OCT. The receiver operating characteristic (ROC) curves compared...
Purpose . To analyse the visual outcome in wet age-related macular degeneration (AMD) patients depending on number of ranibizumab injections. Methods 51 naïve AMD were retrospectively recorded. Visual acuity (VA), central retinal thickness (CRT) measured with spectral domain (SD) optical coherence tomography (OCT), and intravitreal injections compared at 6, 12, 18, 24, 30, 36 months follow-up. Kaplan-Meier survival rates (SRs) based VA outcomes calculated performed. Results improved baseline...