Kun Xuan

ORCID: 0000-0002-8867-9577
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About
Contact & Profiles
Research Areas
  • Sleep and related disorders
  • Early Childhood Education and Development
  • Child and Adolescent Psychosocial and Emotional Development
  • SARS-CoV-2 and COVID-19 Research
  • vaccines and immunoinformatics approaches
  • Resilience and Mental Health
  • SARS-CoV-2 detection and testing
  • Youth Substance Use and School Attendance
  • Mesenchymal stem cell research
  • COVID-19 and healthcare impacts
  • Oral microbiology and periodontitis research
  • Child Nutrition and Feeding Issues
  • Vector-borne infectious diseases
  • Herpesvirus Infections and Treatments
  • Sleep and Wakefulness Research
  • Liver Disease Diagnosis and Treatment
  • Lipoproteins and Cardiovascular Health
  • Birth, Development, and Health
  • Bartonella species infections research
  • Dysphagia Assessment and Management
  • Bone and Dental Protein Studies
  • Toxic Organic Pollutants Impact
  • Primate Behavior and Ecology
  • Helminth infection and control
  • Parkinson's Disease Mechanisms and Treatments

Anhui Provincial Center for Disease Control and Prevention
2023-2024

Nanjing University
2024

Anhui Medical University
2020-2022

Air Force Medical University
2014-2020

Mesenchymal stem cell (MSC) transplantation has been widely applied as a potential therapeutic for multiple diseases. However, the underlying mechanisms are not fully understood, especially paradox between low survival rate of transplanted cells and beneficial effects generated by these cells. Herein, in myocardial infarction (MI) model, we found that MSCs released apoptotic bodies (ABs) to enhance angiogenesis improve cardiac functional reclovery via regulating macroautophagy/autophagy...

10.1080/15548627.2020.1717128 article EN Autophagy 2020-01-21

The Omicron EG.5 lineage of SARS-CoV-2 is currently on a trajectory to become the dominant strain. This phase 2 study aims evaluate immunogenicity SCTV01E-2, tetravalent protein vaccine, with specific emphasis its against EG.5, comparing it progenitor SCTV01E (NCT05933512). As 12 September 2023, 429 participants aged ≥18 years were randomized into groups (N = 215) and SCTV01E-2 214). Both vaccines showed increases in neutralizing antibody (nAb) 5.7-fold increase 9.0-fold 14 days...

10.3390/vaccines12020175 article EN cc-by Vaccines 2024-02-08

Background Varicella is a mild, self-limited disease caused by varicella-zoster virus (VZV) infection. Recently, the burden of varicella has been gradually increasing in China; however, epidemiological characteristics have not reported for Anhui Province. Objective The aim this study was to analyze epidemiology from 2012 2021, which can provide basis future and formulation prevention control policies province. Methods Surveillance data were used characterize 2021 terms population, time,...

10.2196/50673 article EN cc-by JMIR Public Health and Surveillance 2024-04-05

To evaluate the relationship between resilience and emotion regulation among preschool left-behind children (LBC) in rural China. A total of 620 LBC were enrolled from areas Anhui province, Multivariate logistic regression was used to associations variables. The results showed that 20.2% had higher resilience. Emotion correlated with LBC. Children cognitive reconstruction (adjusted OR (AOR) = 0.349,95%CI:0.249-0.489), passive dealing (AOR 0.577, 95%CI:0.411-0.810), alternative action 0.369,...

10.1080/13548506.2020.1849748 article EN Psychology Health & Medicine 2020-11-18

The Omicron EG.5 lineage of SARS-CoV-2 is currently on a trajectory to become dominant strain. This phase 2 study aims evaluate the immunogenicity SCTV01E-2, tetravalent protein vaccine, with specific emphasis its effectiveness against EG.5, comparing it progenitor SCTV01E (NCT05933512). As September 12, 2023, 429 participants aged ≥18 years were randomized (N=215) or SCTV01E-2 (N=214) groups. Both vaccines showed increases in neutralizing antibody (nAb) 5.7-fold increase and 9.0-fold groups...

10.20944/preprints202312.1078.v1 preprint EN 2023-12-15

The importance of social distancing policy Tianming Zhao, Zhao Department Epidemiology and Health Statistics, School Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Kun Xuan, Xuan Chenyu Sun, Sun AMITA Saint Joseph Hospital Chicago, 2900 N. Lake Shore Drive, Chicago 60657, IL, USA https://orcid.org/0000-0003-3812-3164 Yehuan Address correspondence to E-mail:...

10.1093/pubmed/fdaa219 article EN Journal of Public Health 2020-11-05

This study aimed to explore the association between family function and sleep disturbances in preschool children rural areas of China. Caregivers completed sociodemographic questionnaires, Children's Sleep Habits Questionnaire (CSHQ), Self-rating Anxiety Scale (SAS) Family APGAR scale. Using as dependent variable, other related factors independent variables, binary logistic regression analyses were performed examine associations children. A total 3,636 caregivers enrolled our study,...

10.1080/13548506.2022.2032772 article EN Psychology Health & Medicine 2022-01-28

Group living is widespread across diverse taxa, and the mechanisms underlying collective decision-making in contexts of variable role division are critical for understanding dynamics group stability. While studies on behavior small animals such as fish insects well-established, similar research large wild remains challenging due to limited availability sufficient systematic field data. Here, we aimed explore pattern its sexual difference dimorphic Tibetan antelopes Pantholops hodgsonii...

10.1093/cz/zoae036 article EN cc-by-nc Current Zoology 2024-06-26

Many studies have investigated the positivity rate of hepatitis B surface antibody (HBsAb) after vaccine (HepB) immunization. However, level, assessed monthly or at more frequent intervals each three doses, particularly within first year birth, has not been previously reported. To elucidate level formation various times vaccination, current study used available detection data HBsAb in hospitalized children to analyze immunization combined with their vaccination history. Both and geometric...

10.1017/s0950268823001747 article EN cc-by-nc-nd Epidemiology and Infection 2023-01-01

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic which threatened the health of billions individuals across countries all over world.1 Among them, immunocompromised patients, such as HIV-infected individuals, are more vulnerable due to potentially higher risk contracting SARS-CoV-2, especially those with other comorbidities, lower CD4 cell counts, or unsuppressed HIV RNA viral load.2, 3 Previous study...

10.1002/jmv.26378 article EN Journal of Medical Virology 2020-07-31

Abstract Objective Sleep disturbances have been serious since they are believed to be associated with various health problems in preschool children. In this study, we aimed explore the prevalence of sleep amongst children rural areas China and examine underlying factors. Methods A cross-sectional study was conducted Anhui province, from September 2019 January 2020. To potential factors comprehensively, caregivers completed a structured questionnaire, Children’s Habits Questionnaire (CSHQ),...

10.1101/2020.10.20.20215806 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-10-21

<sec> <title>BACKGROUND</title> Varicella is a mild, self-limited disease caused by varicella-zoster virus (VZV) infection. Recently, the burden of varicella has been gradually increasing in China; however, epidemiological characteristics have not reported for Anhui Province. </sec> <title>OBJECTIVE</title> The aim this study was to analyze epidemiology from 2012 2021, which can provide basis future and formulation prevention control policies province. <title>METHODS</title> Surveillance...

10.2196/preprints.50673 preprint EN 2023-07-10

Abstract Introduction: Colorectal cancer (CRC) is a commonly diagnosed cancer, ranking third in prevalence among men and second women. In the United States, CRC leading cause of cancer-related deaths. Periodontal disease (PD), affecting large number adults, may increase risk by prolonged release inflammatory mediators increased carcinogen generation. Compared to normal colon tissue, an Fusobacterium nucleatum, predominant subgingival microbial species chronic periodontitis, was found tumors....

10.1158/1538-7445.am2020-1141 article EN Cancer Research 2020-08-15
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