A5074769051- Stress Responses and Cortisol
- Memory and Neural Mechanisms
- Neuroendocrine regulation and behavior
- Neuroscience and Neuropharmacology Research
- Circadian rhythm and melatonin
- RNA modifications and cancer
- Muscle activation and electromyography studies
- Fusion and Plasma Physics Studies
- RNA Research and Splicing
- Barrier Structure and Function Studies
- Cerebrovascular and genetic disorders
- Neurological Disease Mechanisms and Treatments
- Diet and metabolism studies
- Genetics and Neurodevelopmental Disorders
- Nutritional Studies and Diet
Indian Institute of Science Bangalore
2024
National Centre for Biological Sciences
2009-2021
Manipal Academy of Higher Education
2018-2021
Tata Institute of Fundamental Research
2012-2018
University of California, Santa Barbara
2010
Eastern Virginia Medical School
2010
Central Institute of Mental Health
2010
Rockefeller University
2010
Johns Hopkins Medicine
2010
Johns Hopkins University
2010
Prolonged and severe stress leads to cognitive deficits, but facilitates emotional behaviour. Little is known about the synaptic basis for this contrast. Here, we report that in rats subjected chronic immobilization stress, long-term potentiation (LTP) NMDA receptor (NMDAR)-mediated responses are enhanced principal neurons of lateral amygdala, a brain area involved fear memory formation. This accompanied by electrophysiological morphological changes consistent with formation ‘silent...
Previous studies have demonstrated that repeated immobilization and restraint stress cause contrasting patterns of dendritic reorganization as well alterations in spine density amygdalar hippocampal neurons. Whether social ethologically relevant stressors can induce similar morphological plasticity remains largely unexplored. Hence, we assessed the effects defeat on neuronal morphology basolateral amygdala (BLA), CA1 infralimbic medial prefrontal cortex (mPFC). Male Wistar rats experienced 5...
There are large individual differences in the way animals, including humans, behaviorally and physiologically cope with environmental challenges opportunities. Rodents either a proactive or reactive coping style not only differ their capacity to adapt successfully conditions, but also have differential susceptibility develop stress-related (psycho)pathologies when fails. In this study, we explored if there structural neuronal spine density brain regions important for regulation of stress...
Abstract Background Studies on the relationship between diet and cognition have been predominantly from urban Western populations. However, dietary patterns could vary considerably populations rural Indian population has grossly underrepresented in this research We aim to investigate association pattern cognitive functioning an aging, population. Method The current study utilized a cross sectional design, comprising cognitively healthy participants SANSCOG (Srinivaspura Aging Neuro...
In this study, apical dendritic spine density of neurons in hippocampal, amygdalar and prefrontal cortical areas was compared rats that were repeatedly winning or losing social conflicts. Territorial male wild-type Groningen (WTG) allowed multiple daily attacks (>20 times) on intruder males the resident-intruder paradigm. Frequent experiences are known to facilitate uncontrolled aggressive behavior reflected anesthetized which also observed winners study. Both losers socially housed during...