- Sexuality, Behavior, and Technology
- Marriage and Sexual Relationships
- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Cervical Cancer and HPV Research
- LGBTQ Health, Identity, and Policy
- Sex work and related issues
- Genital Health and Disease
- Hepatitis B Virus Studies
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- Palliative Care and End-of-Life Issues
- Poxvirus research and outbreaks
- HIV, TB, and STIs Epidemiology
- Grief, Bereavement, and Mental Health
- Bacillus and Francisella bacterial research
- Evolutionary Psychology and Human Behavior
- RNA modifications and cancer
- Patient Dignity and Privacy
- Homelessness and Social Issues
- Optimism, Hope, and Well-being
- Female Genital Mutilation/Cutting Issues
- Health and Wellbeing Research
- Herpesvirus Infections and Treatments
- Vaccine Coverage and Hesitancy
Maastricht University
2013-2023
GGD Zuid Limburg
2011-2023
National Institute for Public Health and the Environment
2020
Maastricht University Medical Centre
2013-2018
United States Public Health Service
2013
University Medical Center
2013
Public Health Service of Amsterdam
2011
University of Amsterdam
2003
Huisarts en Wetenschap
2001
In the 2022 multicountry mpox (formerly named monkeypox) outbreak, several countries offered primary preventive vaccination (PPV) to people at higher risk for infection. We study vaccine acceptance and its determinants, target tailor public health (communication-) strategies in context of limited supply Netherlands.
Observational postmarketing studies are important to assess vaccine effectiveness (VE). We estimated VE from the bivalent human papillomavirus (HPV) against HPV positivity of and nonvaccine types in a high-risk population.We included all vaccine-eligible women PASSYON study, biennial cross-sectional survey Dutch sexually transmitted infection clinics. Vaginal swabs were analyzed using polymerase chain reaction-based assay (SPF10-LiPA25) able detect 12 (hrHPV)...
Currently, individuals at risk for sexually transmitted diseases (STDs) are tested extragenitally only if indicated, most often when there is a history of self-reported symptoms or anal sex. The sensitivity such selective symptom- and sexual history-based testing detection anorectal STD has not been determined.All men having sex with (MSM) swingers (heterosexual couples who have other heterosexual their self-identified partners) attending our clinic (consults: n = 1690) from January 2010...
<h3>Background</h3> Identification of STI risk groups is essential for optimal prevention and medical care. Until now, swingers—that is, heterosexual couples who are practising mate swapping, group sex, visit sex clubs couples, not considered as a specific in healthcare services prevention. <h3>Objective</h3> To compare prevalence rates swingers with that other groups. <h3>Methods</h3> At the clinic, South Limburg, The Netherlands, whether an attendee swinger has been systematically...
<h3>Objectives</h3> Recreational drug use has been found to be associated with high-risk sexual behaviour and sexually transmitted infections (STI). This study is the first assess prevalence of among swingers (heterosexuals who, as a couple, practise mate swapping or group sex, and/or visit sex clubs for couples), its association STI. <h3>Methods</h3> We recruited individuals who self-identified visited our STI clinic (from 2009 2012, South Limburg, The Netherlands). Participants (n=289;...
ObjectivesData from a vaccine trial and post-vaccine surveillance in the United Kingdom have suggested that bivalent HPV-16/18 offers cross-protection against HPV-6/11 protection anogenital warts (AGW). We studied effect of on genital positivity AGW Netherlands.MethodsWe included all vaccine-eligible women PASSYON study, biennial cross-sectional study among 16- to 24-year-old sexually transmitted infection (STI) clinic attendants. Vaginal self-swabs were analyzed for type specific HPV...
ABSTRACT Introduction In the global monkeypox outbreak primary preventive vaccination is offered to people at higher risk for infection. We study vaccine acceptance and its determinants, target tailor public health (communication-)strategies in context of limited supply Netherlands. Methods. Online survey a convenience sample gay, bisexual other men who have sex with men, including transgender persons (22/07-05/09/2022, Netherlands). assessed determinants (sociodemographic, social...
Treponema pallidum subsp. is a fastidious spirochete and the etiologic agent of syphilis, sexually transmitted infection (STI). Syphilis diagnoses disease staging are based on clinical findings serologic testing. Moreover, according to most international guidelines, PCR analysis swab samples from genital ulcers included in screening algorithm where possible. It has been suggested that might be omitted due low added value. As an alternative PCR, IgM serology used. In this study, we wanted...
Human papillomavirus (HPV) vaccination programs achieve substantial population-level impact, with effects extending beyond protection of vaccinated individuals. We assessed trends in HPV prevalence up to 8 years postvaccination among men and women the Netherlands, where bivalent vaccination, targeting types 16/18, has been offered (pre)adolescent girls since 2009 moderate coverage.We used data from PASSYON study, a survey initiated (prevaccination) repeated biennially 16- 24-year-old...
Objectives Swingers, that is, members of a heterosexual couple who, as couple, had sex with other couples and/or singles within the swinger’s subculture, are hidden population substantial rates sexually transmitted infections (STIs) and high-risk sexual behaviour. Information on swingers’ self-identification to be swinger, their risk perception attitudes about STI testing safe will help reveal swingers who while in care, address them targeted strategies. Methods We used data from convenience...
Background Concurrent sexual partnerships create higher network connectivity and increase spread of STI through their networks. Recently in our prospective cohort study SWAP (Swingers World Attitude Practice) swingers were identified as a high transmission population for STI. Swingers, heterosexual couples together having sex with others, by definition are involved concurrent relationships. Objective the present paper is to examine indicators level concurrency relations among predicting...
The authors question whether or not age plays a role in the honouring rejection of euthanasia requests Netherlands, where was legalised 2002. They argue that qualitative case studies suggest current application legal requirements due care with regard to (incurable and unbearable suffering, competence, consistency request) leads discrimination against older people who ask for euthanasia. plead systematic research on this problem.
Background Little is known about the epidemiology and burden of sexually transmitted infections (STI) in male commercial sex workers who have with men (MSM-CSWs) Netherlands other Western countries. MSM-CSWs are often hard to reach for prevention STI testing. This feasibility study aimed MSM-CSWs, assess their socio-demographics prevalence HIV STI, risk profile. Methods Retrospective, cross sectional study. Demographic diagnosis data were retrieved from standardised medical records consulted...
Concurrent genital-anal human papillomavirus (HPV) infections may impose an increased anal cancer risk in women with HPV-related genital lesions. High viral load facilitate HPV concurrence. Genital and is reduced by a bivalent HPV16/18 vaccine, yet the effect on concurrent remains unclear. This study analyzed infections, relative to genital-only anal-only impact of vaccination young women. We included 1074 women, who provided both swabs. detection genotyping was performed using...
<h3>ABSTRACT</h3> RNA-binding proteins (RBPs) play important roles in bacterial gene expression and physiology but their true number functional scope remain little understood even model microbes. To advance global RBP discovery bacteria, we here establish glycerol gradient sedimentation with RNase treatment mass spectrometry (GradR). Applied to <i>Salmonella enterica</i>, GradR confirms many known RBPs such as CsrA, Hfq ProQ by RNase-sensitive profiles, discovers the FopA protein a new...
<h3>Background</h3> Despite the availability of regular STI care by clinics and general practitioners many young people at high risk for <i>Chlamydia trachomatis</i> are hidden to care. Members social sexual networks relating Chlamydia positives typically show risk, therefore these members potentially valuable targets interventions. <h3>Methods</h3> Intervention Mapping (IM), a systematic approach develop theory- evidence-based interventions, was used strategy target Ct testing towards who...
Abstract Background Swingers are members of a heterosexual couple who, as couple, have sex with others. They constitute hidden subpopulation that is at risk for sexually transmitted infections (STIs). This study aimed to determine swingers’ level awareness about the STI (indicators: bisexual behaviour, number partners, and status) their swing partners (i.e. alters ). Methods In this cross-sectional study, data were collected from convenience sample swingers who visited our clinic. The...
<h3>Background</h3> Recently, swingers are classified as an emerging high-risk group for STI. A well excepted explanation is that have multiple sex partners, concurrent partnerships and engage in high risk behaviour enabling rapid spread of The present study assessed the prevalence drug use while swinging contribution to STI risk. <h3>Methods</h3> In our cohort we included couples who self identified visited clinic Limburg (2009–2012). Swingers (median age 45 years) filled a administered...
<h3>Background</h3> Non-consensual sexual activity between young people continues to be a major public health problem with long-term negative outcomes. To our knowledge no study has yet evaluated violation and rape separately in girls, boys who have sex men (MSM). <h3>Methods</h3> Data were obtained from ‘sex under the age of 25’, large national on behaviour 10,404 (12–25 years), Netherlands. Current analyses restricted sexually experienced (n = 6,200). Multinomial regression was used...
<h3>Background</h3> During outreach activities of our public health STI-clinic a group young men was encountered, who engaged in internet escort activities. Their commercial sex with took place hidden from sight and regular care. This study aims to describe the STI incidence risk behaviour these male workers having (MSW), compared female (FSW) have (MSM) attending same STI-clinic. <h3>Methods</h3> Retrospective cross-sectional among self-identified MSW, FSW MSM at Netherlands (January...
Background Currently, risk groups are tested only urogenitally by most healthcare providers like general practitioners and STI clinics. Only on indicationmostly guided symptomsanorectal and/or oropharyngeal tests performed. Patient identification thereby adequate treatment interruption of the chain transmission can be hampered when patients positive at another anatomic site than sampled for testing. It is unknown how large this potentially missed burden in is. In study we assessed undetected...
<h3>Background</h3> Swingers, i.e. heterosexual couples who, as a couple, have sex with others within the swingers' subculture, are subpopulation at risk for Sexually Transmitted Infections(STI). Human papillomavirus (HPV) has proven to be highly prevalent in female swingers (unpublished data). The aim of this study is assess how different HPV genotypes distributed sexual networks and whether certain cluster. <h3>Methods</h3> We build network based on data given by 115 who participated our...
<h3>Background</h3> In 2016, a syphilis outbreak was detected among young heterosexuals in the South of Netherlands. Syphilis Dutch is very rare since many years. Here, we describe investigation. <h3>Methods</h3> A case defined as laboratory confirmed sexually transmitted <i>Treponema pallidum</i> diagnosis between April 2016-December 2017 individuals reporting heterosexual behavior only, and who were tested this geographical area. Men having sex with men (MSM), commercial workers swingers...
<h3>Background</h3> Diagnosing an infection with <i>Treponema pallidum,</i> the causative agent of syphilis, is routinely based on serology. STD clinics screen those high-risk sexual behaviour, e.g. MSM, for syphilis. In case ulcus, swabs taken from ulcer can be tested <i>T. pallidum</i> by PCR. Here, we assessed added value PCR next to serology in primary <h3>Methods</h3> Retrospective data were analysed patients our STI clinic. Samples genital and syphilis was simultaneously performed....