A5016528391- Reproductive tract infections research
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Syphilis Diagnosis and Treatment
- Adolescent Sexual and Reproductive Health
- Urinary Tract Infections Management
- Cervical Cancer and HPV Research
- Sex work and related issues
- Pelvic floor disorders treatments
- Hepatitis B Virus Studies
- Sexuality, Behavior, and Technology
- Hepatitis C virus research
- Genital Health and Disease
- COVID-19 epidemiological studies
- HIV Research and Treatment
- COVID-19 and Mental Health
- Viral-associated cancers and disorders
- Long-Term Effects of COVID-19
- Health disparities and outcomes
- Reproductive Health and Contraception
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- LGBTQ Health, Identity, and Policy
- HIV, TB, and STIs Epidemiology
- Marriage and Sexual Relationships
GGD Zuid Limburg
2016-2025
Maastricht University
2016-2025
Maastricht University Medical Centre
2014-2024
Zorginstituut Nederland
2021-2023
University Medical Center
2010-2022
Sexual Health Clinic
2019-2022
Public Health Service of Amsterdam
2002-2020
Public Health England
2020
United States Public Health Service
2013
International Center for Public Health
2013
In the 2022 multicountry mpox (formerly named monkeypox) outbreak, several countries offered primary preventive vaccination (PPV) to people at higher risk for infection. We study vaccine acceptance and its determinants, target tailor public health (communication-) strategies in context of limited supply Netherlands.
Objectives To evaluate the effect of highly active antiretroviral therapy (HAART) on sexual behaviour homosexual men, we conducted (i) an ecological study time trends in and sexually transmitted diseases; (ii) a HAART-effect focused practice unprotected anogenital sex. Design Subjects were participants ongoing Amsterdam Cohort Studies (ACS) among initiated 1984. Data for represented all ACS visits by HIV-1-positive -negative who entered at or below 30 years age followed until 35 (n = 1062)....
Objective: To investigate longitudinally the association between highly active antiretroviral therapy (HAART)-related beliefs and change from protected to unprotected anal intercourse with casual partners on an individual level. Methods: The study population included 217 HIV-negative homosexual men participating in Amsterdam Cohort Study September 1999 May 2002, including five data waves a 6-month interval. selection criteria were: being under 31 years of age, having had sex preceding 6...
Background: The finding of antibodies against human herpesvirus 8 (HHV-8) is associated with the occurrence Kaposi's sarcoma in persons infected HIV. However, predictive value HHV-8 for HIV infection unknown. Methods: Amsterdam Cohort Studies on and AIDS started 1984 homosexual men 1985 injecting drug users. Serum samples from 1459 1167 users were tested to recombinant lytic-phase capsid (ORF65) antigen latent-phase nuclear (ORF73) antigen. Individuals retrospectively identified as...
Objectives In China, in the early 1980s, sexually transmitted diseases (STD) started to increase steeply. Sex workers and their clients appeared play an important role spread of STD. Prostitution is illegal therefore no specific services exist for sex unless they are arrested detained re-education centres. Staff a maternal neonatal hospital Guangzhou felt need STD care prevention programme outside detention, within hospital, which was unique Chinese context. Methods From March 1998...
Identification of sexually transmitted infections (STI) is limited by the infrequent assessment rectal STI. This study assesses usability self-collected swabs (SRS) in diagnosing Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG).In 2006 to 2007, clients Amsterdam South Limburg STI outpatient clinics reporting receptive anal intercourse were asked fill out a questionnaire provide SRS. A standard provider-collected swab (PRS) was also taken, both tested for CT NG nucleic acid...
Abstract Background We evaluated the risk of pelvic inflammatory disease (PID), ectopic pregnancy, and infertility in women with a previous Chlamydia trachomatis (CT) diagnosis compared who tested negative for CT untested women, considering both targeted incidental (ie, prescribed another indication) use CT-effective antibiotics. Methods This was retrospective study aged 12–25 years at start follow-up within Clinical Practice Research Datalink GOLD database linked to index multiple...
Objectives A better understanding of Chlamydia trachomatis infection (chlamydia)–related sequelae can provide a framework for effective chlamydia control strategies. The objective this study was to estimate risks and risk factors pelvic inflammatory disease (PID), ectopic pregnancy tubal factor infertility (TFI) with follow-up time up until 8 years in women previously tested the Screening Implementation (CSI) participating Netherlands Cohort Study (NECCST). Methods Women who participated CSI...
Drug use during sex (‘chemsex’) has been associated with sexually transmitted infections (STIs) and mental health harms. Little quantitative evidence exists on the care needs of MSM practicing chemsex from a patient perspective. This study assessed self-perceived benefits harms for professional counselling among chemsex. In 2018, 785 were recruited at nine Dutch STI clinics 511 (65%) completed online questionnaire. Chemsex was defined as using cocaine, crystal meth, designer drugs, GHB/GBL,...
We assess monkeypox vaccination acceptance among male adults in the European Region. conducted an online survey through two dating apps targeting men who have sex with men, from 30 July to 12 August 2022. developed Bayesian hierarchical logistic regression models investigate acceptance. Overall crude was 82% and higher north-western compared south-eastern regions. Acceptance strongly rose perception of increased disease severity transmission risk, individuals linked healthcare.
Abstract Home-based sexual health care (including self-sampling testing) could reduce barriers to clinic-based testing. This study systematically evaluated the implementation of home-based (‘Limburg4Zero’) among men who have sex with (MSM) in a mixed urban–rural region Netherlands. We assessed outcomes (contextual domains, population reached, effectiveness, adoption by providers (HCP), fidelity, and maintenance) using practical, robust sustainability model. used mixed-methods research design...
Sexual and nonsexual modes of transmission human herpesvirus 8 (HHV8) have been suggested, but specific routes remian unclear. Therefore, the objective this study was to assess risk factors for HHV8 seropositivty determine sexual practice associated with seroconversion. Sera from 1, 458 homosexual men (Amsterdam Cohort Study, 1984–1996) were tested antibodies a modified version an enzyme immunoassay, using recombinant lytic phase capsid (ORF65) latent nuclear (ORF73) proteins. seroprevalence...
Dramatic increases have occurred in sexually transmitted diseases (STD) and sexual risk behaviour among homosexual men Amsterdam internationally. We investigated whether these trends indicate a resurgence of the HIV epidemic.HIV incidence was determined attendees an STD clinic Amsterdam, who had participated semi-annual anonymous unlinked cross-sectional prevalence studies from 1991 to 2001. Stored HIV-seropositive samples were tested with less-sensitive assay and, if non-reactive, further...
Introduction Human herpesvirus 8 (HHV-8), also known as 'Kaposi's sarcoma-associated herpesvirus' (KSHV), was first identified in 1994 [1]. Its discovery is a good example of how epidemiological and molecular-biological data can be combined to evaluate causality for putative agent [2]. In fact, before the HHV-8, analysis surveillance had suggested that, HIV-infected individuals, there existed an infectious co-factor other than HIV that critical development Kaposi's sarcoma (KS), leading...
Anorectal and pharyngeal infections with Chlamydia trachomatis (CT) Neisseria gonorrheae (NG) are commonly observed in men who have sex (MSM). There is increasing evidence that such at extra-genital sites also common women. In both sexes, these largely overlooked as they not routinely tested for regular care. Testing based on sexual behavior or symptoms would only detect half of infections. This paper elucidates the differences similarities between women MSM, regarding epidemiology CT NG. It...
Social isolation is associated with type 2 diabetes (T2DM), but it unclear which elements play a crucial role in this association. Therefore, we assessed the associations of broad range structural and functional social network characteristics normal glucose metabolism, pre-diabetes, newly diagnosed T2DM previously T2DM.Participants originated from The Maastricht Study, population-based cohort study (n = 2861, mean age 60.0 ± 8.2 years, 49% female, 28.8% (oversampled)). were through name...
The intentional use of drugs to have sex-chemsex-among men who sex with (MSM) might contribute the high sexually transmitted infections (STI) prevalence in this group. Limited data is available on chemsex outside major cities. current study investigated a wide variety during among MSM living cities Netherlands and their associations STI.In 2018, 350 were recruited at STI clinics 250 completed an online questionnaire. Questionnaire linked clients' most recent laboratory test results. Chemsex...
Symptom- and sexual history-based testing i.e., on indication, for anorectal sexually transmitted infections (STIs) in women is common. Yet, it unknown whether this strategy effective. Moreover, little known about alternative transmission routes i.e. by fingers/toys. This study assesses STI prevalence missed current practice, thereby informing the optimal control STIs women.Women (n = 663) attending our STI-clinic between May 2012-July 2013 were offered routine urogenital Chlamydia...
Rectal infections with Chlamydia trachomatis (CT) are prevalent in women visiting a sexually transmitted infection outpatient clinic, but it remains unclear what the most effective treatment is. We assessed effectiveness of doxycycline and azithromycin for rectal vaginal chlamydia women.This study is part prospective multicenter cohort (FemCure). Treatment consisted (100 mg twice daily 7 days) CT-positive women, (1 g single dose) vaginally positive who were rectally untested or negative....
Currently, individuals at risk for sexually transmitted diseases (STDs) are tested extragenitally only if indicated, most often when there is a history of self-reported symptoms or anal sex. The sensitivity such selective symptom- and sexual history-based testing detection anorectal STD has not been determined.All men having sex with (MSM) swingers (heterosexual couples who have other heterosexual their self-identified partners) attending our clinic (consults: n = 1690) from January 2010...
Background. In early 2009, a dairy-goat annex care farm in South Limburg, the Netherlands, reported 220 Coxiella burnetii–related abortions 450 pregnant goats. These preceded human cases and occurred region that was Q-fever free before providing unique quasi-experimental setting for investigating regional transmission patterns associated with point source. Methods. Index-farm residents/employees, visitors, their household contacts were traced screened C. burnetii. Distribution of community...