A5091090642- Reproductive tract infections research
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Syphilis Diagnosis and Treatment
- Urinary Tract Infections Management
- Reproductive Health and Contraception
- Cervical Cancer and HPV Research
- Genital Health and Disease
- HIV, TB, and STIs Epidemiology
- HIV, Drug Use, Sexual Risk
- Pelvic floor disorders treatments
- Clinical practice guidelines implementation
- HIV Research and Treatment
- Health and Medical Studies
- Healthcare Systems and Technology
- HIV/AIDS drug development and treatment
- Pediatric health and respiratory diseases
- Health Promotion and Cardiovascular Prevention
- Herpesvirus Infections and Treatments
- Urinary and Genital Oncology Studies
- Emergency and Acute Care Studies
- Dutch Social and Cultural Studies
- Chronic Disease Management Strategies
- Sexuality, Behavior, and Technology
- Hepatitis C virus research
Aidsfonds
2012-2023
University of Amsterdam
2013-2023
Amsterdam University Medical Centers
2019-2023
National Institute for Public Health and the Environment
2011-2022
Amsterdam UMC Location University of Amsterdam
2005-2021
Huisarts en Wetenschap
2002-2021
National Centre for Infectious Diseases
2021
Dutch Expert Centre for Screening
2018
AIDS United
2016
University of Antwerp
2009-2015
<b>Objective</b> To evaluate the effectiveness of register based, yearly chlamydia screening. <b>Design</b> Controlled trial with randomised stepped wedge implementation in three blocks. <b>Setting</b> Three regions Netherlands: Amsterdam, Rotterdam, and South Limburg. <b>Participants</b> 317 304 women men aged 16-29 years listed on municipal registers at start trial. <b>Intervention</b> From March 2008 to February 2011, Chlamydia Screening Implementation programme offered screening tests....
Objectives A better understanding of Chlamydia trachomatis infection (chlamydia)–related sequelae can provide a framework for effective chlamydia control strategies. The objective this study was to estimate risks and risk factors pelvic inflammatory disease (PID), ectopic pregnancy tubal factor infertility (TFI) with follow-up time up until 8 years in women previously tested the Screening Implementation (CSI) participating Netherlands Cohort Study (NECCST). Methods Women who participated CSI...
<b>Objectives:</b><i>Chlamydia trachomatis</i> (Chlamydia) is the most prevalent sexually transmitted bacterial infection and can cause considerable reproductive morbidity in women. Chlamydia screening programmes have been considered but policy recommendations are hampered by lack of population based data. This paper describes prevalence 15–29 year old women men rural urban areas, as determined through systematic organised Municipal Public Health Services (MHS), discusses implications this...
To describe, using routine data in selected countries, chlamydia control activities and rates of infection, pelvic inflammatory disease (PID), ectopic pregnancy infertility to compare trends positivity with PID pregnancy.Cross-national comparison including national from Australia, Denmark, the Netherlands, New Zealand, Sweden Switzerland. Routine sources about diagnosis testing International Classification Disease-10 coded diagnoses PID, women aged 15-39 years 1999 2008 were described....
National surveillance data from 2006 to 2010 of the Dutch sexually transmitted infection (STI) centres were used analyse current practices on testing extragenital sites for chlamydia and gonorrhoea in men who have sex with (MSM) women. In MSM, 76.0% 88.9% tested at least one site (pharyngeal and/or anorectal) gonorrhoea, respectively; women this was 20.5% 30.2%. Testing more than anatomic differed by STI centre, ranging 2% 100%. MSM multiple sites, 63.0% 66.5% diagnoses, respectively, would...
Background: Chlamydia is the most commonly reported bacterial sexually transmitted infection in Europe. The objective of Screening for Europe (SCREen) project was to describe current and planned chlamydia control activities Methods: authors sent a questionnaire asking about different aspects epidemiology public health clinical experts each country 2007. principles were used develop typology comprising five categories activities. Each assigned category, based on responses questionnaire....
In the Netherlands, an Internet-based Chlamydia Screening Implementation was initiated in 3 regions, aiming to reduce population prevalence by annual testing and treatment of people aged 16 29 years. We studied who reached first screening round relating participation chlamydia positivity sociodemographic sexual risk factors.Data from 2008/2009 were analyzed (261,025 invitations, 41,638 participants). Participation rates adjusted for sexually active population. Sociodemographic behavioral...
Abstract We assessed whether infection with chlamydia increases the incidence of carcinogenic human papillomavirus ( HPV ) infections and if persistence is affected by co‐infection. For 1982 women (16–29 years‐old) participating in two consecutive rounds a screening implementation trial, swabs were polymerase chain reaction tested to detect 14 genotypes. type‐specific rates stratified for positivity at follow‐up. Associations multilevel logistic regression analyses correction sexual risk...
Genital herpes results in considerable morbidity, including risk of neonatal herpes, and is increasingly being caused by Herpes Simplex Virus (HSV) type 1. Possibly children are less often HSV-1 infected, leaving them susceptible until sexual debut. We assessed changes the Dutch HSV-2 seroprevalence over time determinants associated with HSV seropositivity.We used data from two population-based seroepidemiological studies conducted 1995-6 2006-7 a similar study design. Serum samples 6 months...
Public health efforts are needed to encourage young women get tested for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC).To assess the acceptability feasibility of 2 noninvasive diagnostic approaches.Participants this cross-sectional survey were 413 (age 16-35) who underwent STD testing by self-taken vaginal swab (SVS) a first-catch urine sample (FCU) nucleic acid amplification test (BDProbTec) filled out questionnaire.CT GC diagnosed in 10.9% (45/413) 1.5% (6/413). Eleven percent...
The study assessed the acceptability of internet-based Chlamydia screening using home-testing kits among 16- to 29-year-old participants and nonparticipants in first year a Screening Implementation program Netherlands.Questionnaire surveys were administered randomly selected (acceptability survey) (nonresponse 3 regions Netherlands where was offered. Participants received email invitations an online survey; postal questionnaires. Both enquired into opinions on design, reasons for (non-)...
Men who have sex with men (MSM) acute human immunodeficiency virus (HIV) infection (AHI) are a key source of new infections. To curb transmission, we implemented strategy for rapid AHI diagnosis and immediate initiation combination antiretroviral therapy (cART) in Amsterdam MSM. We assessed its effectiveness diagnosing decreasing the time to viral suppression.We included 63 278 HIV testing visits 2008-2017, during which 1013 MSM were diagnosed. Standard care (SOC) confirmation < 1 week cART...
In order to increase case-detection of Chlamydia trachomatis (CT) in a multicultural, low-income and high-CT-prevalence neighbourhood, novel approach was piloted collaboration with the pharmacy health centre. During two-year period, women aged 15-29 years who collected their contraceptives at were offered CT-test materials. Home-collected urine could be mailed laboratory general practitioner received results. Nine percent respondents CT-positive (14% among 15-24 year-olds). There strong...
In the Netherlands, sexually transmitted infection (STI) care is provided by general practitioners (GPs) as well specialised STI centres. Consultations at centres are monitored extensively, but data from practice limited. This study aimed to examine consultations in practice.Prospective observational patient survey.General practices within nationally representative Dutch Sentinel GP network (n=125 000 population), 2008-2011.GPs were asked fill out a questionnaire each consultation addressing...
In view of possible type replacement upon introduction human papillomavirus (HPV) vaccination, we aimed to explore patterns type-specific clustering across populations with various background infection risks. A total 3,874 women from 3 cross-sectional studies in the Netherlands (in 2007-2009) provided vaginal self-samples, which were tested for 25 HPV genotypes by a sensitive molecular assay (SPF10 line probe assay, DDL Diagnostic Laboratory, Voorburg, Netherlands). The number concurrent...
<h3>Objective</h3> In three pilot regions of the Netherlands, all 16–29 year olds were invited to participate in annual rounds Chlamydia screening. The aim present study is evaluate cost-effectiveness repeated screening, based on empirical data. <h3>Methods</h3> A mathematical model was employed estimate influence screening prevalence and incidence Chlamydial infection. simulating natural history combined with cost utility data number major outcomes quality-adjusted life-years (QALYs)...