A5075003920- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Health disparities and outcomes
- Cardiovascular and exercise physiology
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Body Composition Measurement Techniques
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health and Lifestyle Studies
- Dementia and Cognitive Impairment Research
- Cardiac Health and Mental Health
- Diet and metabolism studies
- Chronic Disease Management Strategies
- Urban Transport and Accessibility
- Adipokines, Inflammation, and Metabolic Diseases
- Mobile Health and mHealth Applications
- Frailty in Older Adults
- Retinal Imaging and Analysis
- Diabetes Management and Education
- Thermoregulation and physiological responses
- Cardiovascular Disease and Adiposity
- Health and Wellbeing Research
- Balance, Gait, and Falls Prevention
Maastricht University
2016-2025
Maastricht University Medical Centre
2004-2024
VieCuri Medisch Centrum
2023-2024
Zorginstituut Nederland
2023
Netherlands Institute for Social Research
2023
Landscape Research Group
2023
Authorised Association Consortium
2023
Radboud University Nijmegen
2023
Radboud University Medical Center
2023
University Medical Center Utrecht
2023
OBJECTIVE This study examined the association between objectively measured sedentary activity and metabolic syndrome among older adults. RESEARCH DESIGN AND METHODS Data were from 1,367 men women, aged ≥60 years who participated in 2003–2006 National Health Nutrition Examination Survey (NHANES). Sedentary time during waking hours was by an accelerometer (<100 counts per minute). A bout defined as a period of >5 min. break interruption (≥100 Metabolic according to Adult...
<b>Objective</b> To examine whether observed differences in dementia rates between black and white older people living in the community could be explained by measures of socioeconomic status (income, financial adequacy, education, literacy) health related factors. <b>Design</b> Prospective cohort study. <b>Setting</b> General from two clinic sites United States (Pittsburgh, Pennsylvania Memphis, Tennessee). <b>Participants</b> 2457 (mean age 73.6 years; 1019 (41.5%) black; 1233 (50.2%)...
Sedentary behavior has emerged as a novel health risk factor independent of moderate to vigorous physical activity (MVPA). Previous studies have shown self-reported sedentary time be associated with mortality; however, no investigated the effect objectively measured on mortality MVPA. The objective our study was examine association between and all-cause mortality.
Background.An excessive amount of adipose tissue may contribute to sarcopenia and be one mechanism underlying accelerated loss muscle mass strength with aging. We therefore examined the association baseline total body fat changes in leg lean mass, strength, quality over 7 years follow-up whether this link was explained by adipocytokines insulin resistance.
The study investigated cross-sectional associations of total amount and patterns sedentary behaviour with glucose metabolism status the metabolic syndrome.We included 2,497 participants (mean age 60.0 ± 8.1 years, 52% men) from Maastricht Study who were asked to wear an activPAL accelerometer 24 h/day for 8 consecutive days. We calculated daily time, number breaks prolonged bouts (≥30 min), average duration bouts. To determine status, underwent oral tolerance test. Associations variables...
Background: Type 2 diabetes (T2DM) is associated with an increased risk of cardiovascular disease. This can be partly explained by large-artery dysfunction, which already occurs in prediabetes (“ticking clock hypothesis”). Whether a similar phenomenon also applies to microvascular dysfunction not known. We therefore tested the hypothesis that present and more severe T2DM. To do so, we investigated associations prediabetes, T2DM, measures hyperglycemia function measured as flicker...
We aimed to examine the effects of breaking sitting with standing and light-intensity walking vs an energy-matched bout structured exercise on 24 h glucose levels insulin resistance in patients type 2 diabetes. In a randomised crossover study, 19 diabetes (13 men/6 women, 63 ± 9 years old) who were not using each followed three regimens under free-living conditions, lasting 4 days: (1) Sitting: 4415 steps/day 14 sitting/day; (2) Exercise: 4823 1.1 h/day replaced by moderate-...
We examined total activity, light and moderate-to-vigorous physical activity (MVPA) as predictors of mortality in a nationally representative sample older adults. Then we explored the theoretical consequences replacing sedentary time with same duration or MVPA.Using accelerometer-measured associations between (100-2019 counts per minute), MVPA (>2019 minute) were adults age 50 to 79 yr National Health Nutrition Examination Survey, 2003-2006 (n = 3029), follow-up through December 2011. Cox...
Vigorous physical activity (VPA) is a time-efficient way to achieve recommended (PA) for cancer prevention, although structured longer bouts of VPA (via traditional exercise) are unappealing or inaccessible many individuals.To evaluate the dose-response association device-measured daily vigorous intermittent lifestyle (VILPA) with incident cancer, and estimate minimal dose required risk reduction 50% maximum reduction.This was prospective cohort analysis 22 398 self-reported nonexercising...
Abstract Background and Aims Physical inactivity, sedentary behaviour (SB), inadequate sleep are key behavioural risk factors of cardiometabolic diseases. Each is mainly considered in isolation, despite clear biological interdependencies. The aim this study was to investigate associations five-part movement compositions with adiposity biomarkers. Methods Cross-sectional data from six studies (n = 15 253 participants; five countries) the Prospective Activity, Sitting Sleep consortium were...
The protective mechanisms by which some obese individuals escape the detrimental metabolic consequences of obesity are not understood. This study examined differences in body fat distribution and adipocytokines older persons with without syndrome. Additionally, we whether mediate association between Data were from 729 men women (BMI ≥ 30 kg/m(2)), aged 70-79 participating Health, Aging Body Composition (Health ABC) study. Thirty-one percent these did have Obese syndrome had significantly...
The authors examined the association between waist circumference and mortality among 154,776 men 90,757 women aged 51–72 years at baseline (1996–1997) in NIH-AARP Diet Health Study. Additionally, combined effects of body mass index (BMI; weight (kg)/height (m)2) were examined. All-cause was assessed over 9 follow-up (1996–2005). After adjustment for BMI other covariates, a large (fifth quintile vs. second) associated with an approximately 25% increased risk (men: hazard ratio (HR) = 1.22,...
A growing body of evidence has consistently shown a correlation between obesity and chronic subclinical inflammation. It is unclear whether the size specific adipose depots more closely associated with concentrations inflammatory markers than overall adiposity. This study investigated relationship computerized tomography-derived abdominal visceral subcutaneous fat thigh intermuscular in older white black adults. Data were from 2,651 men women aged 70-79 years participating Health, Aging,...
Background: objectively measured population physical activity (PA) data from older persons is lacking. The aim of this study was to describe free-living PA patterns and sedentary behaviours in Icelandic men women using accelerometer. Methods: April 2009 June 2010, 579 AGESII-study participants aged 73–98 years wore an accelerometer (Actigraph GT3X) at the right hip for one complete week settings. Results: all subjects, time largest component total wear time, 75%, followed by low-light PA,...