A5089614039- Vitamin D Research Studies
- Smoking Behavior and Cessation
- Cancer Risks and Factors
- Heart Failure Treatment and Management
- Chronic Kidney Disease and Diabetes
- Nutritional Studies and Diet
- Congenital Heart Disease Studies
- COVID-19 and healthcare impacts
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Behavioral Health and Interventions
- Bone health and osteoporosis research
- Cardiac Valve Diseases and Treatments
- COVID-19 Clinical Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Diabetes Treatment and Management
- Respiratory viral infections research
- Healthcare cost, quality, practices
- Cardiovascular Function and Risk Factors
- Chronic Disease Management Strategies
- Effects and risks of endocrine disrupting chemicals
- Metabolism, Diabetes, and Cancer
- Frailty in Older Adults
- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
University of Oxford
2016-2025
National Institute for Health Research
2021-2024
Health Foundation
2024
Oxford BioMedica (United Kingdom)
2019-2023
Nuffield Health
2018-2022
National Health Service
2022
Oxford Biomedical Research
2019-2021
Oxford University Hospitals NHS Trust
2019
Heidelberg University
2013-2018
German Cancer Research Center
2013-2018
Abstract Objectives To report reliable estimates of short term and long survival rates for people with a diagnosis heart failure to assess trends over time by year diagnosis, hospital admission, socioeconomic group. Design Population based cohort study. Setting Primary care, United Kingdom. Participants care data 55 959 patients aged 45 new 278 679 age sex matched controls in the Clinical Practice Research Datalink from 1 January 2000 31 December 2017 linked inpatient Hospital Episode...
The cardiovascular and kidney benefits of sodium-glucose co-transporter-2 (SGLT2) inhibitors in people with chronic disease (CKD) are well established. implementation updated SGLT2 inhibitor guidelines prescribing the real-world CKD population remains largely unknown.
Chronic kidney disease (CKD) is a largely asymptomatic condition of diminished renal function, which may not be detected until advanced stages without screening.To establish undiagnosed and overall CKD prevalence using cross-sectional analysis.Longitudinal cohort study in UK primary care.Participants aged ≥60 years were invited to attend screening visits determine whether they had reduced function (estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m2 or albumin:creatinine ratio ≥3...
Aims In people with heart failure (HF), a high body mass index (BMI) has been linked better outcomes (‘obesity paradox’), but there is limited evidence in community populations across long-term follow-up. We aimed to examine the association between BMI and survival patients HF large primary care cohort. Methods included incident aged ≥45 years from Clinical Practice Research Datalink (2000–2017). used Kaplan-Meier curves, Cox regression penalised spline methods assess of pre-diagnostic BMI,...
Several observational studies assessed the relationship between serum 25-hydroxyvitamin D [25(OH)D] concentrations and risk of cancer but results were inconclusive.We measured 25(OH)D in a population-based cohort study 9,949 men women ages 50 to 74 years Saarland, Germany. Comprehensively adjusted Cox regression models applied estimate HRs 95% confidence intervals (CI) for association season-standardized total site-specific incidence.Overall, during median 8 follow-up, 873 subjects developed...
Smoking accounts for a large share of lung cancer. F2RL3 methylation was recently identified as biomarker closely reflecting both current and past smoking exposure. We aimed to assess the associations with cancer incidence mortality. In population-based cohort study, measured in baseline blood samples 4,987 participants by MassARRAY. Associations incidence/mortality during median follow-up 10.9 years were assessed Cox regression, controlling potential confounders. The ability predict...
Interventions to reduce the saturated fat (SFA) content of food purchases may help SFA consumption and lower cardiovascular risk. This factorial RCT aimed examine effect altering default order foods being offered a swap on selected during an online shopping experiment.
Aims To understand gender differences in the prognosis of women and men with heart failure, we compared mortality, cause death survival trends over time. Methods results We analysed UK primary care data for 26 725 29 234 age 45 years a new diagnosis failure between 1 January 2000 31 December 2017 using Clinical Practice Research Datalink, inpatient Hospital Episode Statistics Office National registry. Age‐specific overall cause‐specific mortality rates were calculated by year. During study...