A5087953038- Building Energy and Comfort Optimization
- Infection Control in Healthcare
- Dental Research and COVID-19
- Antibiotic Use and Resistance
- Clostridium difficile and Clostridium perfringens research
- Healthcare Facilities Design and Sustainability
- Conservation Techniques and Studies
- Thermoregulation and physiological responses
- Bacteriophages and microbial interactions
- Urban Planning and Valuation
- Water Systems and Optimization
- Medical Device Sterilization and Disinfection
- Probiotics and Fermented Foods
- Antibiotic Resistance in Bacteria
- Gut microbiota and health
- Nosocomial Infections in ICU
- 3D Surveying and Cultural Heritage
- Climate Change and Health Impacts
- Building materials and conservation
- Urban Heat Island Mitigation
- SARS-CoV-2 detection and testing
- Antimicrobial agents and applications
- Infection Control and Ventilation
- Infrared Thermography in Medicine
- Cultural Heritage Materials Analysis
University of Ferrara
2012-2025
Abstract Background The microbiome of the oral cavity is second-largest and diverse microbiota after gut, harboring over 700 species bacteria including also fungi, viruses, protozoa. With its niches, a very complex environment, where different microbes preferentially colonize habitats. Recent data indicate that has essential functions in maintaining systemic health, emergence 16S rRNA gene next-generation sequencing (NGS) greatly contributed to revealing complexity bacterial component....
Background Healthcare-Associated Infections (HAIs) are one of the most frequent complications occurring in healthcare facilities. Contaminated environmental surfaces provide an important potential source for transmission many healthcare-associated pathogens, thus indicating need new and sustainable strategies. Aim This study aims to evaluate effect a novel cleaning procedure based on mechanism biocontrol, presence survival several microorganisms responsible HAIs (i.e. coliforms, Staphyloccus...
Background Contamination of hospital surfaces by clinically-relevant pathogens represents a major concern in healthcare facilities, due to its impact on transmission healthcare-associated infections (HAIs) and the growing drug resistance HAI-associated pathogens. Routinely used chemical disinfectants show limitations controlling pathogen contamination, their inefficacy preventing recontamination selection resistant strains. Recently we observed that an innovative approach, based cleanser...
Healthcare Associated Infections (HAI) are a global concern, further threatened by the increasing drug resistance of HAI-associated pathogens. On other hand, persistent contamination hospital surfaces contributes to HAI transmission, and it is not efficiently controlled conventional cleaning, which does prevent recontamination, has high environmental impact can favour selection drug-resistant microbial strains. In search for effective approaches, an eco-sustainable probiotic-based cleaning...
Purpose: Antimicrobial resistance (AMR) is one of the major threats to human health, and high frequency resistant pathogens in hospital environment can contribute transmission difficult-to-treat health care-associated infections (HAIs).We recently reported that, compared with conventional chemical cleaning, use a microbial-based sanitation strategy (Probiotic Cleaning Hygiene System [PCHS]) was associated remodulation microbiota reduction HAI incidence.Here, we aimed analyze impact PCHS on...
The COVID-19 pandemic has highlighted the extent to which public transportation environment, such as in subways, may be important for transmission of potential pathogenic microbes among humans, with possibility rapidly impacting large numbers people. For these reasons, sanitation procedures, including massive use chemical disinfection, were mandatorily introduced during emergency and remain place. However, most disinfectants have temporary action a high environmental impact, potentially...
It is important to characterize the microorganisms involved in biodeterioration processes understand their effects on cultural assets and define an efficient strategy for protecting artworks, monuments, buildings from microbiological recolonization. In this study, we analyzed microbial communities dwelling verso (front) recto (back) sides of a 17th century easel painting attributed Carlo Bononi, Italian artist first Baroque period. Cultivable bacteria fungi colonizing were isolated...
The biodeterioration process involves every type of Cultural Heritage item, including monuments, stoneworks, frescoes, and easel paintings. accurate study the microbial fungal communities dwelling on artworks, involved in their deterioration, is essential for adoption optimal prevention conservation strategies. Conventional restorative methods, that usually involve chemical physical technologies, present some disadvantages, short-term unsatisfactory effects, potential damage to treated...
The high and sometimes inappropriate use of disinfectants antibiotics has led to alarming levels Antimicrobial Resistance (AMR) water hearth pollution, which today represent major threats for public health. Furthermore, the current SARS-CoV-2 pandemic deeply influenced our sanitization habits, imposing massive chemical potentially exacerbating both concerns. Moreover, super-sanitation can profoundly influence environmental microbiome, resulting counterproductive when trying stably eliminate...
Indoor air quality (IAQ) plays a vital role in supporting both the physical and mental well-being of individuals enclosed spaces, mechanical ventilation systems has gained increasing attention due to building design’s focus on energy efficiency thus airtight constructions. This study investigated pre–post effects installing heat recovery system (MVHR) indoor high school classroom Ferrara, Italy. The analysis focused experimental measurements temperature (T), relative humidity (RH), carbon...
The indoor microbiome is a dynamic ecosystem including pathogens that can impact human health. In this regard, the school environment represents main living space of humans for many years, and an unhealthy significantly condition students’ School rooms suffer from insufficient ventilation use building materials may favor pathogen contamination, mostly sanitized by conventional chemical-based methods, which pollution, have temporary effects, induce selection antimicrobial resistance (AMR) in...
The hospital environment significantly contributes to the onset of healthcare associated infections (HAIs), representing most frequent and severe complications related health care. monitoring surfaces is generally addressed by microbial cultural isolation, with some performance limitations. Hence there need implement environmental surveillance systems using more effective methods. This study aimed evaluate next-generation sequencing (NGS) technologies for microbiome characterization, in...
Antimicrobial resistance (AMR) represents a major threat to public health, especially in the hospital environment, and massive use of disinfectants prevent COVID-19 transmission might intensify this risk, possibly leading future AMR pandemics. However, control microbial contamination is crucial hospitals, since microbiomes can cause healthcare-associated infections (HAIs), which are particularly frequent severe pediatric wards due children having high susceptibility.We have previously...
Purpose: Many hospital-acquired infections (HAIs) can be transmitted by pathogens contaminating hospital surfaces, not efficiently controlled conventional sanitation, which indeed contribute to the selection of MDR strains. Bacteriophages have been suggested as decontaminating agents, based on their selective ability kill specific bacteria. However, there are no data stability in detergents and potential use routine sanitation. On other hand, a probiotic-based sanitation system (Probiotic...
This study investigated for the first time decontamination efficacy of a probiotic-based cleaning product containing Bacillus subtilis, pumilus, and megaterium spores on fresh reused broiler litters during 3 rearing cycles 6 wk each. Moreover, impact treated with chicken caeca microbiota was assessed at end in comparison to untreated litter. The provided treatment were able successfully colonize poultry litters, decreasing mean counts total aerobic bacteria, Enterobacteriaceae, coagulase...
High-risk Human Papillomaviruses (hrHPV) are causally related to Cervical Intraepithelial Neoplasia (CIN) and subsequent cervical cancer (CC). The vaginal microbiome has been suggested play a role in the development of CC, but surgical treatment on hrHPV elimination is not elucidated. This study aimed characterize inflammatory chemokine profile 85 women treated for CIN2-CIN3 lesions, before after CIN removal. Results showed, as expected, high prevalence dysbiotic microbiomes pro-inflammatory...
Infants born before 28 weeks are at risk of contracting healthcare-associated infections (HAIs), which could be caused by pathogens residing on contaminated hospital surfaces. In this longitudinal study, we characterized NGS the bacterial composition nasal swabs preterm newborns, time birth and after admission to Neonatal Intensive Care Unit (NICU), comparing it with that environmental wards delivery during hospitalization. We resistome samples too. The results showed microorganisms...
Microbial contamination in the hospital environment is a major concern for public health, since it significantly contributes to onset of healthcare-associated infections (HAIs), which are further complicated by alarming level antimicrobial resistance (AMR) HAI-associated pathogens. Chemical disinfection control bioburden has temporary effect and can favor selection resistant pathogens, as observed during COVID-19 pandemic. Instead, probiotic-based sanitation (probiotic cleaning hygiene...
Large windows with increased exposure to daylight have strong positive effects on the well-being of building occupants and can provide energy savings when appropriate glazing specifications are employed. The work evaluates impact different window sizes heating cooling needs in a hospital patient room, order investigate achievable by adopting wider openings identify most effective types. Simulations been conducted for commercially available systems. authors analyzed performance base case 25%...