A5100700913- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Spinal Cord Injury Research
- Ubiquitin and proteasome pathways
- Nerve injury and regeneration
- Signaling Pathways in Disease
- interferon and immune responses
- Systemic Lupus Erythematosus Research
- Heat shock proteins research
- RNA Research and Splicing
- Medical Research and Treatments
- Cytokine Signaling Pathways and Interactions
- Circular RNAs in diseases
- Cancer-related Molecular Pathways
- Ferroptosis and cancer prognosis
- Spondyloarthritis Studies and Treatments
- Neonatal and fetal brain pathology
- Spinal Hematomas and Complications
- RNA modifications and cancer
- Sphingolipid Metabolism and Signaling
- Erythrocyte Function and Pathophysiology
- Mesenchymal stem cell research
- Cell death mechanisms and regulation
- Ergonomics and Musculoskeletal Disorders
Nanjing Medical University
2023
Jiangsu Province Hospital
2023
Second Affiliated Hospital of Nanchang University
2022
Nanchang University
2022
First Affiliated Hospital of Zhengzhou University
2007-2021
Jinzhou Medical University
2020
Yangzhou University
2019
Shanghai East Hospital
2011
Recent evidence has suggested that the 1,25(OH)2D3/Vitamin D receptor (VDR) acts to suppress immune response associated with systemic lupus erythematosus (SLE), a serious multisystem autoimmune disease. Hence, aim of current study was investigate mechanism by which 1,25-(OH)2D3/VDR influences SLE through regulating Skp2/p27 signaling pathway.Initially, levels 1,25(OH)2D3, VDR, Skp2, and p27 were measured in collected renal tissues peripheral blood. Meanwhile, inflammatory factors,...
Osteosarcoma (OS) is a malignant bone cancer, in which circular RNAs (circRNAs) act as important modulators. The present study aimed to explore the functional role of circRNA itchy E3 ubiquitin protein ligase (circITCH) development and doxorubicin (DXR) resistance OS possible mechanistic pathway.A quantitative real-time polymerase chain reaction or western blot assays were exploited analyze expression circITCH, miR-524 Ras association domain family member 6 (RASSF6). Cell viability...
ObjectiveNeural stem cells play an important role in the recovery and regeneration of peripheral nerve injury, microRNA-7 (miR-7) regulates differentiation neural cells. This study aimed to explore miR-7 homing proliferation its influence on injury repair. MethodsThe mice model was created by segmental sciatic defect (sciatic injury), treatment performed with a gelatin hydrogel conduit containing inserted into mice. The Sciatic Function Index used quantify functional messenger RNA protein...
Intervertebral disc degeneration (IDD) is a prevalent disease characterized by low back pain. Increasing extracellular matrix (ECM) synthesis and decreasing nucleus pulposus cell (NPC) apoptosis are promising strategies to recover degenerated NP. LIM mineralization protein- (LMP-) 1 has anti-inflammatory potential gene target for the treatment of NP degeneration. In this study, we measured expression LMP-1 in patients. Then, constructed LMP-1-overexpressing NPCs using lentiviral vectors...
<title>Abstract</title> Background Work-related musculoskeletal disorders (WMSDs) significantly affect bus drivers’ health and warrant adequate attention. This study aimed to explore the associations of occupational stress with WMSDs among drivers, assess potential mediating role sleep quality nighttime duration. Methods A total 1792 drivers available information from 5 subsidiaries Shenzhen Bus Group by convenient sampling method were included. Logistic regression model was used estimate...
Liver carcinoma is one of the most common cancers in world and remains difficult to treat. Hepatocellular cancer important type liver (90%). RING Finger 44 (RNF44) E3 ligases, which play an role substrate recognition. It was also reported that connected with resistant melanoma. But relationship between RNF44 HCC remained unknown.To analyze gene hepatocellular carcinoma, we used bioinformatics expression level, genetic changes, immunohistochemistry, immune infiltration, diagnostic value,...