Jack A. Heinemann

ORCID: 0000-0002-9074-9052
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About
Contact & Profiles
Research Areas
  • CRISPR and Genetic Engineering
  • Bacteriophages and microbial interactions
  • Genetically Modified Organisms Research
  • Antibiotic Resistance in Bacteria
  • Bacterial Genetics and Biotechnology
  • Animal Genetics and Reproduction
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Insect Resistance and Genetics
  • Agricultural Innovations and Practices
  • Evolution and Genetic Dynamics
  • Transgenic Plants and Applications
  • Salmonella and Campylobacter epidemiology
  • Plant tissue culture and regeneration
  • Environmental DNA in Biodiversity Studies
  • Intellectual Property and Patents
  • Botanical Research and Chemistry
  • Agriculture, Land Use, Rural Development
  • Legume Nitrogen Fixing Symbiosis
  • Plant and animal studies
  • Microbial infections and disease research
  • Bacillus and Francisella bacterial research
  • Fungal and yeast genetics research
  • Listeria monocytogenes in Food Safety
  • Identification and Quantification in Food
  • TiO2 Photocatalysis and Solar Cells

University of Canterbury
2015-2024

Christ University
2019

GenØk
2010-2012

Google (United States)
2005

National Institute of Allergy and Infectious Diseases
1993-1996

National Institutes of Health
1996

Rocky Mountain Research (United States)
1994

University of Oregon
1989

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10.1126/science.1158390 article EN Science 2008-04-17

A broad community of independent scientific researchers and scholars challenges recent claims a consensus over the safety genetically modified organisms (GMOs). In following joint statement, claimed is shown to be an artificial construct that has been falsely perpetuated through diverse fora. Irrespective contradictory evidence in refereed literature, as documented below, claim there now on GMOs continues widely often uncritically aired. For decades, hotly controversial topic much debated...

10.1186/s12302-014-0034-1 article EN cc-by Environmental Sciences Europe 2015-01-23

Biocides, such as herbicides, are routinely tested for toxicity but not sublethal effects on microbes. Many biocides known to induce an adaptive multiple-antibiotic resistance phenotype. This can be due either increase in the expression of efflux pumps, a reduced synthesis outer membrane porins, or both. Exposures Escherichia coli and Salmonella enterica serovar Typhimurium commercial formulations three herbicides-dicamba (Kamba), 2,4-dichlorophenoxyacetic acid (2,4-D), glyphosate...

10.1128/mbio.00009-15 article EN cc-by-nc-sa mBio 2015-03-25

Bacteriophages infecting Salmonella spp. were isolated from sewage using soft agar overlays containing three serovars and assessed with regard to their potential control food-borne salmonellae. Two distinct phages, as defined by plaque morphology, structure host range, obtained a single sample of screened sewage. Phage FGCSSa1 had the broadest range six eight isolates neither two Escherichia coli isolates. Under optimal growth conditions for S. Enteritidis PT160, phage infection resulted in...

10.1111/j.1574-6968.2006.00217.x article EN FEMS Microbiology Letters 2006-04-03

An agroecosystem is constrained by environmental possibility and social choices, mainly in the form of government policies. To be sustainable, an requires production systems that are resilient to natural stressors such as disease, pests, drought, wind salinity, human constructed economic cycles trade barriers. The world becoming increasingly reliant on concentrated exporting agroecosystems for staple crops, vulnerable national local decisions affect resilience these systems. We chronicle...

10.1080/14735903.2013.806408 article EN cc-by International Journal of Agricultural Sustainability 2013-06-14

Antimicrobial resistance (AMR) threatens human and ecological health worldwide. Unless major changes occur across the human, animal environmental sectors, problem will continue to expand. An important component of AMR that deserves greater attention is influence emerging organic contaminants (EOCs) – ubiquitous compounds found, amongst others, in pharmaceuticals, personal care products, food, industrial agricultural plastics building materials. EOCs are widely used can accumulate environment...

10.1016/j.emcon.2021.07.001 article EN cc-by-nc-nd Emerging contaminants 2021-01-01

Postsegregational killing (PSK) systems consist of a tightly linked toxin–antitoxin pair. Antitoxin must be continually produced to prevent the longer lived toxin from cell. PSK on plasmids are widely believed benefit plasmid by ensuring its stable vertical inheritance. However, experimental tests this “stability” hypothesis were not consistent with predictions. We suggest an alternative explain evolution PSK: that have been selected through benefiting host in environments where compete...

10.1073/pnas.220077897 article EN Proceedings of the National Academy of Sciences 2000-10-31

Antibiotic resistance in our pathogens is medicine's climate change: caused by human activity, and resulting more extreme outcomes. Resistance emerges microbial populations when antibiotics act on phenotypic variance within the population. This can arise from either genotypic diversity (resulting a mutation or horizontal gene transfer), differences expression due to environmental variation, referred as adaptive resistance. Adaptive changes increase fitness allowing bacteria survive at higher...

10.7717/peerj.5801 article EN cc-by PeerJ 2018-10-12

Abstract TiO 2 photocatalyst is of interest for antimicrobial coatings on hospital touch-surfaces. Recent research has focused visible spectrum enhancement photocatalytic activity. Here, we report with a high degree nanostructure, deposited stainless steel as solid layer more than 10 μm thick by pulsed-pressure-MOCVD. The coating exhibits rarely-reported microstructure comprising anatase and rutile in composite amorphous carbon. Columnar single crystals are segmented into 15–20 nm plates,...

10.1038/s41598-018-38291-y article EN cc-by Scientific Reports 2019-02-13

Changing the nature, kind and quantity of particular regulatory-RNA molecules through genetic engineering can create biosafety risks. While some genetically modified organisms (GMOs) are intended to produce new molecules, these may also arise in other GMOs not express them. To characterise, assess then mitigate potential adverse effects arising from changes RNA requires changing current approaches food or environmental risk assessments GMOs. We document assessment advice offered government...

10.1016/j.envint.2013.02.010 article EN cc-by-nc-nd Environment International 2013-03-20

Herbicides are frequently released into both rural and urban environments. Commercial herbicide formulations induce adaptive changes in the way bacteria respond to antibiotics. Salmonella enterica sv. Typhimurium Escherichia coli were exposed common co-formulants of formulations, S. was active ingredients dicamba, 2,4-D glyphosate determine what commercial caused this effect. Co-formulants Tween80 carboxymethyl cellulose induced response, but pattern responses differed from ingredients,...

10.1099/mic.0.000573 article EN cc-by Microbiology 2017-11-15

10.1016/s1359-6446(98)01294-x article EN Drug Discovery Today 1999-02-01

Helicobacter pylori is highly susceptible to bismuth, a heavy metal with antimicrobial activity linked its effect on bacterial iron uptake. Three strains of H. were analyzed for indicators limitation following exposure the MIC colloidal bismuth subcitrate (MIC(CBS)). Similar morphologic and outer membrane changes observed growth in iron-limiting medium at MIC(CBS) that inhibited all three strains. These changes, which also iron-limited bacteria, alleviated by addition cultures. ATP levels,...

10.1128/aac.48.6.1983-1988.2004 article EN Antimicrobial Agents and Chemotherapy 2004-05-21

To isolate and characterize bacteriophages (phages) that infect the foodborne pathogen Bacillus cereus.Two phages were isolated from soil based on their ability to form plaques four indicator hosts including thuringiensis subsp. israelensis, three isolates of B. cereus. The purified characterized by morphology, host range, single-step growth curves restriction enzyme digestion profiles. appeared be Myoviridae family structure in electron micrographs. lysed bacteria several species, produced...

10.1111/j.1472-765x.2011.03023.x article EN Letters in Applied Microbiology 2011-02-07

CRISPR/Cas9, a potent genetic engineering tool widely adopted in agriculture, is capable of introducing new characteristics into plants on large scale and without conventional breeding methods. Despite its remarkable efficiency, concerns have arisen regarding unintended consequences uncontrolled environments. Our aim was to assess potential activity organisms that could be exposed genome editing We developed three scenarios, using irrigation, fumigation fertilization as delivery methods,...

10.1016/j.ecoenv.2024.116707 article EN Ecotoxicology and Environmental Safety 2024-07-12
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