- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Gastrointestinal Tumor Research and Treatment
- Sarcoma Diagnosis and Treatment
- Mast cells and histamine
- Oral and Maxillofacial Pathology
- Virus-based gene therapy research
- Cutaneous lymphoproliferative disorders research
- Hypertrophic osteoarthropathy and related conditions
- Angiogenesis and VEGF in Cancer
- Lymphoma Diagnosis and Treatment
University of Liverpool
2020-2023
Animal Health Trust
2018
Objectives To describe the clinicopathological and genetic characteristics of mast cell tumours in dogs less than 12 months old. Materials Methods Retrospective review aged when diagnosed with at three referral hospitals UK. Results Sixteen pure‐bred were included, which 11 female. The median age first presentation diagnosis 7.6 9 months, respectively. In 13 cutaneous they subcutaneous. Four described as high‐grade (Patnaik or Kiupel) nine Patnaik grade II; had mitotic index >5 10...
Abstract A 13‐year‐old, female, neutered, domestic, shorthair cat presented with a history of weight loss and vomiting. An intra‐abdominal mass was palpated during clinical examination, total hypercalcaemia noted on biochemistry. Imaging findings were consistent jejunal mass, which surgically resected, an end‐to‐end anastomosis performed. No other obvious signs metastatic disease observed. The resolved after 14 days, histopathology results identified leiomyosarcoma, confirmed by...
Hematological indices play a prognostic role in human osteosarcoma (OSA), but data are limited dogs. The aim of this retrospective multicentric cohort study was to investigate the significance pre-operative hematological/inflammatory client-owned dogs with appendicular OSA receiving standardized treatment. Cut-offs associated progression-free survival (PFS) for hematological values/ratios were established using minimal p-value approach. Historical factors also assessed. Statistical analyses...
This study aimed to describe the management of cases suspected and confirmed canine multicentric lymphoma (ML) in first opinion practice (FOP) investigate whether socioeconomic factors are associated with initial management.
Abstract An adult female spayed Bichon Frise with history of chronic pruritus, atopy and intermittent ear infections was presented for the assessment generalised erythema, multiple cutaneous nodules, otitis externa exudative dermatitis only partially temporarily responsive to oclacitinib systemic antibiotic treatment. Several investigations were performed, a diagnosis epitheliotropic lymphoma (CETL) circulating neoplastic lymphocytes (Sézary syndrome [SS]) CD3 + CD4 CD8 − immunophenotype...