A5047174925- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- Colorectal and Anal Carcinomas
- Cutaneous Melanoma Detection and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- BRCA gene mutations in cancer
- Economic and Financial Impacts of Cancer
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Immunotherapy and Immune Responses
- Metastasis and carcinoma case studies
- HER2/EGFR in Cancer Research
- Healthcare Policy and Management
- Sarcoma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Nonmelanoma Skin Cancer Studies
- Cancer Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Thyroid Cancer Diagnosis and Treatment
OASIS Clinic
2016-2024
Albert Einstein College of Medicine
2021-2022
Torrey Pines Institute For Molecular Studies
2017
Oasis Charitable Trust
2017
City Of Hope National Medical Center
2012-2015
City of Hope
2011-2014
National Cancer Center
2013
University of California, Davis
2008-2012
UC Davis Comprehensive Cancer Center
2010-2011
University of California Davis Medical Center
2008-2011
To determine whether analyzing more lymph nodes in colon cancer specimens improves survival.Increasing the number of analyzed has been reported to correlate with improved survival patients node-negative cancer.The Surveillance, Epidemiology, and End Results database was queried for all undergoing resection histologically confirmed between years 1988 2000. Patients were excluded distant metastases or if an unknown sampled. The sampled categorized into 0, 1 7, 8 14, > =15 nodes. Survival...
In Brief Objective: To determine the role of chemokine receptor (CR) expression in patients with melanoma and colorectal cancer (CRC) liver metastases. Summary Background Data: Murine vitro models have identified CR as potential factors organ-specific metastasis multiple cancers. Chemokines via their respective receptors been shown to promote cell migration distant organs. Methods: Patients who underwent hepatic surgery for or CRC metastases were assessed. Screening cDNA microarrays...
The American Society of Breast Surgeons (ASBrS) endorses the Board Internal Medicine’s Choosing Wisely campaign statement: “Don’t routinely perform a double mastectomy in patients who have single breast with cancer.”1 However, women newly diagnosed unilateral cancer are increasingly opting for bilateral mastectomy. This has been seen candidates conservation elect as well those requiring their index cancer.2 National rates contralateral prophylactic (CPM) United States increasing and this...
In Brief Objective: The 25% rate of recurrence after complete resection stage II colon cancer (CC) suggests the presence occult nodal metastases not identified by hematoxylin and eosin staining (H&E). Interim data from our ongoing prospective multicenter trial sentinel node (SN) biopsy indicate a 29.6% micrometastases (MM) immunohistochemical (IHC) H&E-negative SNs in CC. We hypothesized that these MM have prognostic importance. Methods: Between March 2001 August 2006, 152 patients with...
The presence and number of nodal metastasis significantly impact colon cancer prognosis. Similarly, the resected/evaluated nodes impacts staging accuracy. This ratio metastatic to examined or lymph node (LNR) may have independent prognostic value in carcinoma.: To evaluate LNR on overall survival patients with fewer than 12 more.Patients (n = 36,712) node-positive nonmetastatic diagnosed between 1992 2004 were identified from Surveillance, Epidemiology, End Results database stratified...
With the goal of improving intraoperative cancer visualization, we have developed AVB-620, a novel intravenously administered, in vivo fluorescent peptide dye conjugate that highlights malignant tissue and is optimized for human use. Matrix metalloproteinases (MMPs) hydrolyze AVB-620 triggering retention ratiometric fluorescence color change which visualized using camera systems capable imaging white light simultaneously. visualizes primary tumors demonstrated high diagnostic sensitivity...
Adjuvant radiation is rarely used to treat medullary thyroid carcinoma (MTC). We hypothesized that external beam therapy (EBRT) would improve overall survival (OS) in MTC patients.The Surveillance, Epidemiology, and End Results (SEER) database identified patients who underwent total thyroidectomy lymph nodes excision for between 1988 2004. The Kaplan-Meier method was univariate comparisons of OS. Multivariate Cox proportional hazards models controlled gender, age, node status, tumor size,...
The role of adjuvant radiation therapy (RT) for adenoid cystic carcinoma (ACC) the breast remains unclear.We queried Surveillance, Epidemiology, and End Results database patients with ACC resected between 1988 2005, divided based on receipt RT. Univariate multivariate survival comparisons were made overall disease-specific survival.Three hundred seventy six met criteria inclusion. Demographics staging similar groups. analysis revealed an absolute cause-specific benefit 21% 7% at 10 years (P...
In Brief Objective: Because appropriate rectal cancer care and subsequent outcomes can be influenced by several variables, our objective was to investigate how race, ethnicity, socioeconomic status (SES) may impact outcomes. Background: The management of requires a multidisciplinary approach utilizing medical surgical subspecialties. Methods: We performed an investigation patients with adenocarcinoma from Los Angeles County 1988 2006 using the Cancer Surveillance Program. Clinical pathologic...
Chinese translation Background: Computer-aided detection (CAD) has rapidly diffused into screening mammography practice despite limited and conflicting data on its clinical effect. Objective: To determine associations between CAD use during the incidence of ductal carcinoma in situ (DCIS) invasive breast cancer, cancer stage, diagnostic testing. Design: Retrospective cohort study. Setting: Medicare program. Participants: Women aged 67 to 89 years having 2001 2006 U.S. SEER (Surveillance,...
It is unknown whether the number of lymph nodes harvested (lymph node yield, LNY) or proportion metastatic resected (metastatic ratio, MLNR) influence survival in well-differentiated thyroid carcinoma (WDTC). We hypothesized that overall WDTC influenced by LNY and MLNR. used Surveillance, Epidemiology, End Results database to identify all patients with primary, nonmetastatic who underwent thyroidectomy at least one removed between 1988 2004. Kaplan-Meier curves for MLNR were compared using...
Abstract Background and Objectives The practice of aggressive contiguous organ resection (COR) retroperitoneal sarcoma (RPS) is controversial. We examined rates 30‐day morbidity mortality following RPS utilizing data from the American College Surgeons National Surgical Quality Improvement Program (ACS‐NSQIP) database. Methods From 2005 to 2007, we identified 156 cases primary malignant neoplasm retroperitoneum. Univariate multivariate analyses were performed using all pre‐operative ACS‐NSQIP...