A5027649682- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Ear Surgery and Otitis Media
- Advanced Fluorescence Microscopy Techniques
- Thermography and Photoacoustic Techniques
- Retinal and Macular Surgery
- Nanoplatforms for cancer theranostics
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Endodontics and Root Canal Treatments
- Optical Imaging and Spectroscopy Techniques
- Semiconductor Lasers and Optical Devices
- Advanced Optical Network Technologies
- Periodontal Regeneration and Treatments
- Advanced Photonic Communication Systems
- Laser Applications in Dentistry and Medicine
- Retinal Imaging and Analysis
- Dental Implant Techniques and Outcomes
- Nasal Surgery and Airway Studies
- Dental Radiography and Imaging
- Orthodontics and Dentofacial Orthopedics
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Optical Polarization and Ellipsometry
- Psychosocial Factors Impacting Youth
- Sinusitis and nasal conditions
Kyungpook National University
2016-2024
Harvard University
2023-2024
Pulmonary and Critical Care Associates
2024
Massachusetts General Hospital
2023-2024
University of California, Los Angeles
2021-2023
Pusan National University
2020
Idiopathic pulmonary fibrosis (IPF) affects the subpleural lung but is considered to spare small airways. Micro-computed tomography (micro-CT) studies demonstrated airway reduction in end-stage IPF explanted lungs, raising questions about involvement early-stage disease. Endobronchial optical coherence (EB-OCT) a volumetric imaging modality that detects microscopic features from proximal
Spatial sampling density and data size are important determinants of the imaging speed photoacoustic microscopy (PAM). Therefore, undersampling methods that reduce number scanning points typically adopted to enhance PAM by increasing step size. Since sacrifice spatial density, considering points, size, characteristics provides three-dimensional (3D) volume data, in this study, we newly reported deep learning-based fully reconstructing undersampled 3D data. The results quantitative analyses...
The aim of this study was to analyze the effectiveness decalcification using ethylenediaminetetraacetic acid (EDTA) as an optical clearing method enhance depth visibility internal soft tissues cochlea. Ex vivo mouse and guinea pig cochlea samples were soaked in EDTA solutions for decalcification, swept source coherence tomography (OCT) used imaging modality monitor decalcified consecutively. monitored noninvasive cross-sectional images showed that had be subsequent 7 14 days, respectively,...
Corneal transplantation by full-thickness penetrating keratoplasty with human donor tissue is a widely accepted treatment for damaged or diseased corneas. Although corneal has high success rate, shortage of high-quality considerable limitation. Therefore, bioengineered corneas could be an effective solution this limitation, and decellularized extracellular matrix comprises promising scaffold their fabrication. In study, three-dimensional bioprinted collagen sheets were implanted into the...
A large field-of-view and fast scanning of photoacoustic microscopy (PAM) relatively have been difficult to obtain due the water-drowned structure system for transmission ultrasonic signals. Researchers widely studied achievement a waterproof scanner dynamic biological applications with high-resolution high signal-to-noise ratio. This Letter reports novel, best our knowledge, galvanometer scanner-based PAM successfully attainable ${9.0}\;{\rm mm} \times {14.5}\;{\rm mm}$9.0mm×14.5mm scan...
Significant technical and optical advances are required for intraoperative coherence tomography (OCT) to be utilized during otological surgeries. Integrating OCT with surgical microscopy makes it possible evaluate soft tissue in real-time at a high resolution. Herein, we describe an augmented-reality, OCT/microscope system extended working distance of 280 mm, providing more space manipulation than conventional techniques. We initially performed ex vivo experiments performance. In addition,...
The aim of this study was to quantitatively assess the residual adhesive on orthodontic ceramic bracket-removed dental surface. In process, bracket repeated debonding physically, then remained caused a lack strength between and bracket. Since commonly used in orthodontics is translucent, hard be detected with conventional microscopes. Therefore, 1310 nm center wavelength swept-source OCT system based laboratory customized image processing algorithm for precise detection tooth separates from...
Laser transmission welding offers significant benefits over conventional techniques enabling single-stage rapid plastic joining. The quality of laser welded products is commonly assessed by measuring the weld penetration depth, hardened boundary, and inspecting formation porosity. However, existing methods verification are inevitably accompanied destruction specimen. Thus, non-destructive assessment for have gained attention recently. Here, we demonstrated an extended industrial application...
To identify the vascular alteration by photodynamic therapy (PDT), utilization of high-resolution, high-speed, and wide-field photoacoustic microscopy (PAM) has gained enormous interest. The rapid changes in vasculature during PDT treatment monitoring tumor tissue activation orthotopic pancreatic cancer model have received limited attention previous studies. Here, a fully two-axes waterproof galvanometer scanner-based (WGS-PAM) system was developed for vivo dynamic variations micro blood...
Dental crowns are used to restore decayed or chipped teeth, where their surfaces play a key role in this restoration process, as they affect the fitting and stable bonding of prostheses. The surface texture can interfere with therefore measurement inner roughness is very important but difficult achieve using conventional imaging methods. In study, dental were three-dimensionally (3D) visualized swept-source optical coherence tomography (SS-OCT) system. Nine fabricated commercial 3D printer...
Intraoperative surgical microscopy integrated with optical coherence tomography (OCT) has improved the accuracy and safety of surgeries by providing a visualization sub-surface tissue structure. Although intraoperative OCT resolved conventional limitations microscope, it is still remained to provide additional informative blood vessel-related data that required enhance stability surgery minimizing bleeding damage. In this paper, we developed virtual angiography microscope (VI-OCTA-SM)...
The ischemic stroke animal model evaluates the efficacy of reperfusion and neuroprotective strategies for injuries. Various conventional methods have been reported to induce models; however, controlling specific neurological deficits, mortality rates, extent infarction is difficult as size affected region not precisely controlled. In this paper, we report a single laser-based localized target development method by simultaneous vessel monitoring photothrombosis induction using photoacoustic...
Optical fiber is widely used in optical coherence tomography (OCT) to propagate light precisely with low attenuation and dispersion. However, the total path length within varies accordance changes of temperature. This leads travel interfering signals results shifting OCT image position an unintended depth pixel value. In this paper, we presented temperature-based automatic compensating method limit external temperature effect control micro-scale without manual movement components. By...
Non-invasive characterization of micro-vibrations in the tympanic membrane (TM) excited by external sound waves is considered as a promising and essential diagnosis modern otolaryngology. To verify possibility measuring discriminating vibrating pattern TM, here we describe micro-vibration measurement method latex resembling TM. The measurements are obtained with an externally generated audio stimuli 2.0, 2.2, 2.8, 3.1 3.2 kHz, their respective vibrations based tomographic, volumetric...
Photoacoustic imaging (PAI) is a hybrid non-invasive technique used to merge high optical contrast and acoustic resolution in deep tissue. PAI has been extensively developed by utilizing its advantages that include depth, resolution, label-free imaging. As representative implementation of PAI, photoacoustic microscopy (PAM) preclinical clinical studies for micron-scale spatial capability with absorption contrast. Several handheld portable PAM systems have improve applicability several...
An internal and marginal fit between prosthesis abutment is an important factor of the durability dental prosthesis. In this paper, we have proposed use swept-source optical coherence tomography (OCT) as a novel application for non-ionized high-resolution measurements discrepancies at anatomically critical four points, such occlusal, angle, axial, margin during attachment. A tooth model was fabricated by 3D printing technique, designed using CAD software. The cross-sectional images along...
In the past decade, there has been an increase in development of sensitive, high-resolution, non-invasive diagnostic methods for periodontic diseases. Optical coherence tomography (OCT) attracted considerable attention clinical settings. this paper, a reliable, robust algorithm detection gingival sulcus 2D OCT cross-sectional images is proposed. Previously, measurement performed by manual identification using two-dimensional (2D) images. The automated continuity may help medical...
Depth-visualizing sensitivity can be degraded due to imperfect optical alignment and non-equidistant distribution of signals in the pixel array, which requires a measurement re-sampling process. To enhance this depth-visualizing sensitivity, reference sample arm-channeled spectra corresponding different depths using mirrors were obtained calibrate spectrum sampling prior Fourier transformation. During process, eight interferogram patterns point spread function (PSF) at path length...
The sciatic nerve is the longest and widest single in human body responsible for signal transduction of entire hind limb region. Its wide dynamic range size makes it sensitive to injury. branching location are important, unlike histology, optical coherence tomography (OCT) can provide rapid non-destructive cross-sectional images. nerves ten rats were analyzed using swept-source (SS)-OCT. sufficient depth penetration SS-OCT system allowed clear identification internal bifurcation point...