A5076870449- Cassava research and cyanide
- Natural Antidiabetic Agents Studies
- NF-κB Signaling Pathways
- Head and Neck Cancer Studies
- Glutathione Transferases and Polymorphisms
- Lung Cancer Treatments and Mutations
- Drug-Induced Hepatotoxicity and Protection
- RNA modifications and cancer
- Cancer-related gene regulation
- Malaria Research and Control
- Phytochemical compounds biological activities
- Helicobacter pylori-related gastroenterology studies
- Bone Metabolism and Diseases
- Parasites and Host Interactions
- Cancer Genomics and Diagnostics
- Reproductive Biology and Fertility
- Cytokine Signaling Pathways and Interactions
- Proteoglycans and glycosaminoglycans research
- Pain Management and Placebo Effect
- Bone and Dental Protein Studies
- Heavy Metal Exposure and Toxicity
- Phagocytosis and Immune Regulation
- Sports injuries and prevention
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Ethnobotanical and Medicinal Plants Studies
University of Cape Coast
2016-2025
University of Health and Allied Sciences
2022
University of Southern California
1974
The young leaves of Vernonia amygdalina are often utilized as vegetable and for medicinal purpose compared to the old leaves. This study was designed evaluate compare antidiabetic effects between ethanolic leaf extracts V. on streptozotocin (STZ) induced diabetic rat four weeks. Preliminary screening both revealed presence same phytochemicals except flavonoids which only present in . Difference antioxidant power statistically significant (<mml:math...
Introduction Coronavirus disease 2019 (COVID-19) vaccine hesitancy is a complex health challenge characterized by delay in the acceptance or refusal of vaccination with context-specific determinants. Our study, therefore, assessed COVID-19 among urban dwellers Central Region, Ghana. Methods A cross sectional study was conducted between September and November, 2022 using multi-stage cluster sampling procedure 377 participants. modified World Health Organization pretested paper-based...
Abstract Background Malaria and helminths diseases are co-endemic in most parts of sub-Saharan Africa. Immune responses from each these pathogens interact, interactions may have implications on vaccines. The GMZ2 malaria vaccine candidate is a fusion protein Plasmodium falciparum merozoite surface 3 (MSP3) glutamate rich (GLURP R0). has recently showed modest efficacy phase IIb multicenter trial. Here, we assessed the effect hookworm ( Necator americanus ) infection anthelmintic treatment...
Objectives: Nrf2/BACH1/HO-1 proteins have been implicated in the development and progression of tumors. However, their clinical relevance breast cancer remains unclear understudied. This study evaluated protein expression its relationship with age, tumor grade, stage, TNM, ER, PR, HER2, histologic type. Methods: 114 female 30 noncancerous tissues were for using immunohistochemistry Western blot. The relationships between clinicopathologic factors assessed χ2 test. Results: 74% cancerous...
Heavy metal toxicity contributes to liver and kidney dysfunction damage through oxidative stress mechanisms; however, from previous studies, extracts the Vernonia amygdalina plant have shown possess potent antioxidant properties. This study was aimed at uncovering potential ameliorative effects of ethanolic extract in heavy toxicity-induced dysfunction. For this study, 44 Sprague Dawley rats were divided into three groups. The control group received a basal diet water only while treatment...
Head and neck tumors (HNT) are that normally occur at the head region of body. Epidermal growth factor receptor (EGFR) has been found to be highly expressed in breast other tumors; therefore, there is need investigate level EGFR expression among patients with Ghana.The was determined tumor control tissues quantitative real-time PCR immunohistochemistry analysis.The expressions high than tissues. There a significant difference p value 0.025 ages >40 ≤ 40 when low compared malignant tumor. The...
Background Head and neck tumors (HNT) are of the paranasal sinuses, salivary glands upper aerodigestive tract. RIN1 is a Ras effector protein regulating epithelial cell properties has been implicated in number cancers. Method The aim this study was to investigate expression head tumors. assessed using quantitative real-time PCR (qRT-PCR) immunohistochemical staining on archival tissue samples between 2014 2020. Results low as compared with normal tissues. High levels were ages ≤40, >40...
Abstract Head and neck tumors (HNT) are of paranasal sinuses origin (the salivary glands the upper aerodigestive tract). It constitutes sixth most common tumors. Studies have shown that, factors such as tobacco alcohol intake viral infections may increase relative risk to tumor. Notch1 pathways frequently altered in many tumors, however, clinical significance NOTCH1dysregulation head is poorly understood. METHOD: The aim this study was investigate expression NOTCH1 tumor also elucidate...
scale treatment with benzimidazole has raised concerns about the possible emergence of resistance and decreased efficacy been reported in some studies (Albonico et al., 2004; Keiser Utzinger, 2008).Helminth infections poor settings developing world are a public health concern, especially when they overlap malaria (Reilly 2008).However, interaction between these widely distributed parasites have not extensively investigated.Our previous work on prevalence hookworm infection association...
<h3>Background</h3> Head and neck tumors (HNT) are of paranasal sinuses origin (the salivary glands the upper aerodigestive tract). It constitutes sixth most common tumors. Studies have shown that, factors such as tobacco alcohol intake viral infections may increase relative risk to tumor. RIN1 is a Ras effector protein that regulates epithelial cell properties has been implicated in number Notch1 pathways frequently altered many tumors, however, clinical significance NOTCH1dysregulation...
Abstract Nrf2/BACH1/HO-1 signals have been implicated in the development and progression of tumors. However, there has no comprehensive analysis their expressions breast cancer. This study evaluated expression its clinical significance 114 female cancer different pathologic parameters non-cancerous tissues were for using immunohistochemistry western blot. The relationship connecting clinicopathologic factors assessed chi-square test. Nrf2 protein cancerous (74%) was significantly higher than...
Abstract Abstract: Background: Head and neck Tumour (HNT) are tumour of the paranasal sinuses, salivary glands upper aero¬digestive tract. EGF can stimulate cell proliferation, differentiation, growth, migration, inhibit apoptosis. The aim this study was to investigate expression EGFR in head tumour. Method: analyzed using quantitative real-time PCR (qRT-PCR) immunohistochemical staining on tissue samples from a consecutive series 150 patients who underwent tumor resections between 2014...