A5101658809- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Oral microbiology and periodontitis research
- Acute Ischemic Stroke Management
- Marine Bivalve and Aquaculture Studies
- Pharmacogenetics and Drug Metabolism
- Cerebrovascular and Carotid Artery Diseases
- Oral Health Pathology and Treatment
- Gut microbiota and health
- Dental Radiography and Imaging
- Chemical Synthesis and Characterization
- Protein Hydrolysis and Bioactive Peptides
- Acute Myocardial Infarction Research
- Computational Drug Discovery Methods
- Ammonia Synthesis and Nitrogen Reduction
- SARS-CoV-2 and COVID-19 Research
- Traditional Chinese Medicine Analysis
- Drilling and Well Engineering
- Atherosclerosis and Cardiovascular Diseases
- Water Quality Monitoring Technologies
- Venous Thromboembolism Diagnosis and Management
- Endodontics and Root Canal Treatments
- Inorganic Chemistry and Materials
- Pharmacological Receptor Mechanisms and Effects
- Drug Transport and Resistance Mechanisms
Ludong University
2007-2024
Chongqing Medical University
2022-2023
Stomatological Hospital of Chongqing Medical University
2023
Daiichi Sankyo (United States)
2023
Taizhou Municipal Hospital
2022
The Affiliated Yongchuan Hospital of Chongqing Medical University
2022
National Institutes for Food and Drug Control
2020
Nanjing Medical University
2013
Jiangsu Province Hospital
2013
Background: The authors compare the effectiveness and safety of endovascular treatment (EVT) versus best medical management (BMM) in strokes attributable to acute basilar artery occlusion (BAO). Methods: present analysis was based on ongoing, prospective, multicenter ATTENTION (Endovascular Treatment for Acute Basilar Artery Occlusion) trial registry China. Our analytic sample comprised 2134 patients recruited at 48 sites between 2017 2021 included 462 who received BMM 1672 EVT. We performed...
The primary influencer of aquaculture quality in Amphioctopus fangsiao is pathogen infection. Both lipopolysaccharides (LPS) and polyinosinic:polycytidylic acid (Poly I:C) are recognized by the pattern recognition receptor (PRR) within immune cells, a system that frequently serves to emulate invasion. Hemolymph, which functions as transport mechanism for offers vital transcriptome information when A. exposed pathogens, thereby contributing our comprehension species’ biological mechanisms. In...
<h3>BACKGROUND AND PURPOSE:</h3> Stroke is a leading cause of death and disability, many studies have focused on the evolution FLAIR imaging in acute chronic time window. The purpose this study was to evaluate potential efficacy FLAIR-related techniques identifying onset cerebral ischemia canine embolic stroke model. <h3>MATERIALS METHODS:</h3> An ischemic model generated through use an autologous clot 20 beagle dogs. Both DWI were performed at 3 hours, 4 5 6 24 hours after embolization,...
Over the years, oysters have faced recurring mass mortality issues during summer breeding season, with Vibrio infection emerging as a significant contributing factor. Tubules of gill filaments were confirmed to be in hematopoietic position Crassostrea gigas, which produce hemocytes immune defense capabilities. Additionally, epithelial cells oyster gills effectors defend against pathogens. In light this, we performed transcriptome analysis tissues obtained from C. gigas infected alginolyticus...
The intent of this perspective is to share the recommendations International Consortium for Innovation and Quality in Pharmaceutical Development Metabolite Bioanalysis Working Group on fit‐for‐purpose metabolite bioanalysis support drug development registration. This report summarizes considerations trigger, timing, rigor various assessments address unique challenges due metabolites, with respect efficacy safety, which may arise during from investigational new (IND) enabling studies, phase...
Abstract The gut microbiota is a bridge linking periodontitis and systemic diseases, such as diabetes mellitus (DM). probiotic Clostridium butyricum MIYAIRI 588 (CBM588) reportedly an effective therapeutic approach for dysbiosis. Here, in mouse model, we explored the effect of CBM588 on periodontal bone destruction DM DM‐associated (DMP), well underlying mechanism. Micro‐computed tomography revealed that DMP both aggravated destruction, which was alleviated by intragastric supplementation...
Immune defense systems are indispensable for living organisms. Within an immune network, problems with any given link can impact the normal life activities of organism. Amphioctopus fangsiao is a cephalopod that exists widely throughout world’s oceans. Because its nervous system and locomotive organs, it has become increasingly studied in recent years. Vibrio anguillarum one most common pathogenic bacteria aquaculture It highly infectious infect almost all V. infection cause many adverse...
At present, cancer ranks first as the cause of death in world, necessitating need to develop new anticancer agents. As a probe, biomarkers can indicate biological and pharmacological activity agents are thus valuable predicting their effectiveness during research development phase. This paper reviews on biomarker-guided prediction efficacy We infer that, process agents, reasonable selection improve accuracy
The coronavirus disease 2019 (COVID-19), which is first detected in Wuhan, China, a virus identified as the cause of pneumonia. In event epidemic outbreak, series actions have been taken by Chinese government to control pandemic virus, and effective medical methods are urgent need prevent COVID-19 infection cure disease, especially drug that can suppress urgently needed. However, there no specific drugs vaccine infection. Some research works on transmissibility, severity, other features...
Pathogenic infections significantly limit the culture of marine organisms, such as cephalopods. However, there is a lack immune information regarding cephalopods to address pathogen problems. Polyriboinosinic polyribocytidylic acid (Poly I:C), synthetic virus-like molecule, can be recognized by cells pathogen-associated molecular patterns (PAMPs), and this process often used simulate invasion viruses. The white body an hematopoietic organ, its RNA-seq obtained from Amphioctopus fangsiao...
The insertion reactions of 1XAl (X=H, Na, F, Cl, SH) with polar molecule hydrogen chloride have been investigated at the B3LYP/6-311+G(d, p) level, which three-membered ring transition states (TSs). Moreover, general statistical thermodynamics and Eyring state theory Wigner correction were used to study thermodynamic kinetic properties these reaction channels within temperature range 200–1000 K. It is concluded that rise temperature, equilibrium constant K decreases sharply, while rate k...
Objective To analyze the expression of toll like receptors 4 (TLR4) in patients with different types coronary artery disease (CAD), and to explore association between TLR4 in-stent restenosis (ISR) after percutaneous intervention (PCI). Methods A total 342 who underwent angiography (CAG) because chest pain were enrolled. According angiographic results, divided into control group (n=44) (CAD) (n=298), including 48 cases stable angina pectoris (SAP) 250 acute syndrome (ACS). level was...