Graham A. McCreath

ORCID: 0000-0002-9312-8665
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About
Contact & Profiles
Research Areas
  • Innovations in Medical Education
  • Colorectal Cancer Screening and Detection
  • Esophageal and GI Pathology
  • Interprofessional Education and Collaboration
  • Pancreatic and Hepatic Oncology Research
  • Mental Health and Patient Involvement
  • Viral Infectious Diseases and Gene Expression in Insects
  • Radiology practices and education
  • Fault Detection and Control Systems
  • COVID-19 Clinical Research Studies
  • Cancer-related cognitive impairment studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Dementia and Cognitive Impairment Research
  • Glioma Diagnosis and Treatment
  • Mast cells and histamine
  • Adolescent and Pediatric Healthcare
  • Cardiac, Anesthesia and Surgical Outcomes
  • Clinical Reasoning and Diagnostic Skills
  • Global Health Workforce Issues
  • Intensive Care Unit Cognitive Disorders
  • Neurobiology of Language and Bilingualism
  • Surgical Simulation and Training
  • Identity, Memory, and Therapy
  • Global Health and Surgery
  • Respiratory Support and Mechanisms

SickKids Foundation
2020-2023

University of Toronto
2020-2022

Walsh University
2022

Sheffield Children's NHS Foundation Trust
2021

University of Sheffield
2021

Sheffield Children's Hospital
2021

St. Vincent's Medical Center
2021

Providence St. Vincent Medical Center
2021

Hospital for Sick Children
2020-2021

Fujifilm (United Kingdom)
2018-2019

Multivariate data analysis (MVDA) is a highly valuable and significantly underutilized resource in biomanufacturing. It offers the opportunity to enhance understanding leverage useful information from complex high-dimensional sets, recorded throughout all stages of therapeutic drug manufacture. To help standardize application promote this within biopharmaceutical industry, paper outlines novel MVDA methodology describing necessary steps for efficient effective analysis. The followed solve...

10.1002/biot.201800684 article EN cc-by Biotechnology Journal 2019-10-16

The Canadian Institutes for Health Research launched a national 'Strategy Patient-Oriented Research' (SPOR) in 2011. Patient-oriented research is defined as continuum of that engages patients partners, focuses on patient-identified priorities, and improves patient outcomes. Capacity development core element SPOR. Barriers to patient-oriented include unfamiliarity with the process families methods family engagement researchers.

10.1186/s40900-021-00276-z article EN cc-by Research Involvement and Engagement 2021-05-10

High-quality pediatric gastrointestinal procedures are performed when clinically indicated and defined by their successful performance skilled providers in a safe, comfortable, child-oriented, expeditious manner. The process of endoscopy begins plan to perform the procedure is first made ends all appropriate patient follow-up has occurred. Procedure-related standards indicators developed date for adults emphasize cancer screening thus unsuitable medicine.With support from North American...

10.1097/mpg.0000000000003264 article EN Journal of Pediatric Gastroenterology and Nutrition 2021-08-16

High-quality pediatric endoscopy requires reliable performance of procedures by competent individual providers who consistently uphold all standards determined to assure optimal patient outcomes. Establishing consensus expectations for ongoing monitoring and assessment endoscopists is a method confirming the highest possible quality care such worldwide. We aim provide guidance define measure endoscopic children.With support from North American European Societies Pediatric Gastroenterology...

10.1097/mpg.0000000000003265 article EN Journal of Pediatric Gastroenterology and Nutrition 2021-08-16

<h3>Background:</h3> Patient and family engagement is thought to improve the quality relevance of child health research. We developed evaluated usability Engagement 101, an e-learning module designed strengthen patient-oriented research readiness care professionals, researchers, trainees other stakeholders. <h3>Methods:</h3> The development 101 was co-led by a parent researcher overseen diverse multistake-holder steering committee. refined using mixed-methods testing approach with 2...

10.9778/cmajo.20210336 article EN CMAJ Open 2022-10-01

The regulation of histamine‐induced [ 3 H]‐inositol phosphate formation was studied in human cultured umbilical vein endothelial cells (HUVEC). Histamine (EC50 4.8 μ m ) produced a 12.7 fold increase over basal levels. Prior exposure to 0.1 histamine (2h) 78% reduction the response subsequent (0.1 challenge. IC 50 for this desensitization 0.9 . inositol inhibited by phorbol dibutyrate (IC 40 n ; maximal 64%). This effect antagonized both staurosporine (100 and Ro 31–8220 (10 ). However, H 1...

10.1111/j.1476-5381.1994.tb17067.x article EN British Journal of Pharmacology 1994-11-01

Abstract Background and Objectives Many healthy older adults experience age-related memory changes that can impact their day-to-day functioning. Qualitative interviews have been useful in gaining insight into the of who are facing difficulties. To enhance this insight, there is a need for reliable valid measure quantifies normal on daily living. The primary objective study was to develop validate new instrument, Memory Impact Questionnaire (MIQ). Research Design Methods We examined...

10.1093/geront/gny011 article EN The Gerontologist 2018-02-15

There is increasing international recognition of the impact variability in endoscopy facilities on procedural quality and outcomes. also growing precedent for assessing at regional national levels by using standardized rating scales to identify opportunities improvement.With support from North American European Societies Pediatric Gastroenterology Hepatology Nutrition (NASPGHAN ESPGHAN), an working group Endoscopy Quality Improvement Network (PEnQuIN) used methodological strategy Appraisal...

10.1097/mpg.0000000000003263 article EN Journal of Pediatric Gastroenterology and Nutrition 2021-08-16

Individuals who read more tend to have stronger verbal skills than those less. Interestingly, what you may make a difference. Past studies found that reading narrative fiction, but not expository nonfiction, predicts ability. Why this difference exists is known. Here we investigate one possibility: whether fiction texts contain of the words typically evaluated by ability measures compared nonfiction texts. We employed corpus linguistic analyses compare frequency with which commonly tested...

10.1080/0163853x.2017.1289794 article EN Discourse Processes 2017-03-20

Engaging patients and families as research partners increases the relevance, quality, impact of child health research. However, those interested in engagement may feel underequipped to meaningfully partner. We sought co-develop an online learning (e-learning) module, "Research 101," support capacity-development patient-oriented amongst families. Module co-development was co-led by a parent researcher, with guidance from diverse, multi-stakeholder steering committee. A mixed-methods usability...

10.3389/fped.2022.849959 article EN cc-by Frontiers in Pediatrics 2022-07-06

Purpose Entrustment is central to assessment in competency-based medical education (CBME). To date, little research has addressed how clinical supervisors conceptualize entrustment, including factors they consider making entrustment decisions. The aim of this study was characterize supervisors’ decision related procedural using gastrointestinal endoscopy as a test case. Method Using methods from constructivist grounded theory, the authors interviewed 29 United States and Canada across...

10.1097/acm.0000000000004566 article EN Academic Medicine 2021-12-21

Abstract Background Competency-based medical education (CBME), an educational paradigm that prioritizes development of measurable skills over time in training, is currently being instituted across North American residency training programs. A fundamental goal CBME entrustment – the process whereby supervisors come to trust trainees perform specific tasks without supervision. How decisions are made with respect endoscopic has not been elucidated. Aims We aimed to: (1) identify factors...

10.1093/jcag/gwz047.137 article EN cc-by-nc-nd Journal of the Canadian Association of Gastroenterology 2020-02-01
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