Ying‐Chen Chen

ORCID: 0000-0002-9313-968X
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Research Areas
  • Advanced Memory and Neural Computing
  • Ferroelectric and Negative Capacitance Devices
  • Semiconductor materials and devices
  • Electronic and Structural Properties of Oxides
  • Neuroscience and Neural Engineering
  • Transition Metal Oxide Nanomaterials
  • Nanoparticle-Based Drug Delivery
  • Drug Solubulity and Delivery Systems
  • Photoreceptor and optogenetics research
  • CCD and CMOS Imaging Sensors
  • Mechanical Circulatory Support Devices
  • Asymmetric Synthesis and Catalysis
  • Advanced Drug Delivery Systems
  • Cardiac Arrest and Resuscitation
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cardiac Structural Anomalies and Repair
  • Gas Sensing Nanomaterials and Sensors
  • Catalytic Processes in Materials Science
  • Hydrogels: synthesis, properties, applications
  • Chemical Synthesis and Analysis
  • Advanced Photocatalysis Techniques
  • interferon and immune responses
  • Energy Efficient Wireless Sensor Networks
  • Temporomandibular Joint Disorders
  • Catalysis and Oxidation Reactions

Arizona State University
2023-2025

Changhua Christian Hospital
2015-2025

National Chung Hsing University
2018-2024

Chang Gung Memorial Hospital
2021-2023

Northern Arizona University
2020-2023

Chang Gung University
2023

National Taipei University
2023

National Taiwan University
2007-2022

Chung Shan Medical University
2021-2022

United Hospital
2021

Multifunctional epidermal sensor systems (ESS) are manufactured with a highly cost and time effective, benchtop, large-area "cut-and-paste" method. The ESS made out of thin stretchable metal conductive polymer ribbons can be noninvasively laminated onto the skin surface to sense electrophysiological signals, temperature, hydration, respiratory rate. As service our authors readers, this journal provides supporting information supplied by authors. Such materials peer reviewed may re-organized...

10.1002/adma.201502386 article EN Advanced Materials 2015-09-23

Refractory ventricular fibrillation, resistant to conventional cardiopulmonary resuscitation (CPR), is a life threatening rhythm encountered in the emergency department. Although previous reports suggest use of extracorporeal CPR can improve clinical outcomes patients with prolonged cardiac arrest, effectiveness this novel strategy for refractory fibrillation not known. We aimed compare managed or our institution.This retrospective chart review study from an department tertiary referral...

10.1016/j.resuscitation.2015.04.016 article EN cc-by-nc-nd Resuscitation 2015-05-02

The ever‐increasing processing power demands of digital computers cannot continue to be fulfilled indefinitely unless there is a paradigm shift in computing. Neuromorphic computing, which takes inspiration from the highly parallel, low‐power, high‐speed, and noise‐tolerant computing capabilities brain, may provide such shift. Many researchers across academia industry have been studying materials, devices, circuits, systems, implement some functions networks neurons synapses develop...

10.1002/aisy.201900189 article EN cc-by Advanced Intelligent Systems 2020-03-05

Homeothermic synaptic behaviors with a wide range of temperature were demonstrated in CMOS-compatible HfO<sub>x</sub>/AlO<sub>y</sub> memristors.

10.1039/c8nr06694a article EN Nanoscale 2018-11-27

We report on a highly compact, one diode-one resistor (1D-1R) nanopillar device architecture for SiOx-based ReRAM fabricated using nanosphere lithography (NSL). The intrinsic resistive switching element and Si diode are self-aligned an epitaxial silicon wafer NSL deep-Si-etch process without conventional photolithography. AC-pulse response in 50 ns regime, multibit operation, good reliability demonstrated. provides fast economical approach to large-scale patterning of high-density 1D-1R with...

10.1021/nl404160u article EN Nano Letters 2013-12-26

Abstract We realize a device with biological synaptic behaviors by integrating silicon oxide (SiO x ) resistive switching memory Si diodes. Minimal power consumption due to sneak-path current is achieved and the capability for spike-induced demonstrated, representing critical milestones use of SiO 2 –based materials in future neuromorphic computing applications. Biological such as long-term potentiation (LTP), depression (LTD) spike-timing dependent plasticity (STDP) are demonstrated...

10.1038/srep21268 article EN cc-by Scientific Reports 2016-02-16

A feasible approach is reported to reduce the switching current and increase nonlinearity in a complementary metal-oxide-semiconductor (CMOS)-compatible Ti/SiNx /p+ -Si memristor by simply reducing cell size down sub-100 nm. Even though voltages gradually with decreasing device size, reset reduced because of overshoot effect. The scaled devices (sub-100 nm) exhibit gradual driven electric field, whereas that large (≥1 µm) Joule heating. For (60 nm), levels are tunable adjusting stop voltage...

10.1002/smll.201704062 article EN Small 2018-04-17

Abstract 2D memristors have demonstrated attractive resistive switching characteristics recently but also suffer from the reliability issue, which limits practical applications. Previous efforts on primarily focused exploring new material systems, while damage metallization step remains a concern for of memristors. Here, impact conditions and thickness MoS 2 films other device metrics ‐based is carefully studied. The statistical electrical measurements show that can be improved to 92% yield...

10.1002/adfm.202214250 article EN Advanced Functional Materials 2023-04-13

Multilevel programing and charge transport characteristics of intrinsic SiOx-based resistive switching memory are investigated using TaN/SiOx/n++Si (MIS) TiW/SiOx/TiW (MIM) device structures. Current high- low-resistance states (HRS LRS) studied in both structures during multilevel operation. Analysis thermal response demonstrates that the effective electron energy barrier is strongly dependent on resistance programed state, with estimates 0.1 eV LRS 0.6 HRS. Linear data fitting conductance...

10.1063/1.4891244 article EN Journal of Applied Physics 2014-07-28

Given the growing number of arthritis patients and limitations current treatments, there is great urgency to explore cartilage substitutes by tissue engineering. In this study, we developed a novel decellularization method for menisci prepare acellular extracellular matrix (ECM) scaffolds with minimal adverse effects on ECM. Among all acid formic treatment removed most cellular contents preserved highest ECM in decellularized porcine menisci. Compared fresh menisci, content DNA decreased...

10.1089/ten.tec.2015.0036 article EN Tissue Engineering Part C Methods 2015-04-28

This study proposes a method for HfO2-based device to exhibit both resistive switching (RS) characteristics as random access memory (RRAM) and selector by introducing vanadium (V) the top electrode. simple V/HfO2/TiN structure can demonstrate these two different properties depending on forming polarities. The RS mechanism is activated positive bias. In contrast, property induced negative material analyses firstly confirm existence of V in Then electrical measurements same structures but with...

10.1039/c7nr02305g article EN Nanoscale 2017-01-01

The physical mechanisms of unipolar resistive switching (RS) in SiOx-based memory are investigated using TaN/SiOx/n++Si and TiW/SiOx/TiW device structures. RS is independent SiOx thickness area, confirming that occurs a localized region along filamentary pathway. Results from experiments varying electrode type, series resistance, the oxygen content SiOxNy materials show potential to optimize performance control programming window. Device with stoichiometry near SiO2 found have better...

10.1063/1.4891242 article EN Journal of Applied Physics 2014-07-28

Abstract: Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was develop a lecithin-based mixed polymeric micelle (LMPM) delivery system improve the and bioavailability Que. optimal Que-LMPM, composed Que, lecithin, Pluronic ® P123, 1,2-distearoyl- sn -glycero-3-phosphoethanolamine- N -methoxy[poly(ethylene glycol)-2000] in proportion 3:1:17.5:2.5 (w/w), prepared by thin-film...

10.2147/ijn.s103681 article EN cc-by-nc International Journal of Nanomedicine 2016-04-01

Photocatalysis is an efficient process for degrading organic pollutants and inactivating pathogenic microorganisms. However, this constantly suffers from turbidity shading particle aggregation in a catalyst suspension system, thereby reducing its photocatalytic activity. Immobilizing the photocatalyst on light-transmissible surface viable solution to obstacles. So far, photo-inactivation efficacy between immobilized systems has yet be compared investigated. In study, N-TiO2 (NT)...

10.1016/j.seppur.2024.127298 article EN cc-by-nc Separation and Purification Technology 2024-03-29

Abstract HfOx‐based resistive random‐access‐memory (ReRAM) devices (TiN/Ti/HfOx/RuOx/TiN) are fabricated by CMOS‐compatible materials (ruthenium (Ru)) and lithography‐lite process, potentially enabling a maskless, etching‐free process that can be implemented in the low earth orbit (LEO), International Space Station (ISS), commercial LEO destinations (CLDs). The met requirements for qualified manufacturers list verification (QMLV) radiation hardness assurance (QMLV‐RHA), as well Advanced Next...

10.1002/aelm.202400823 article EN cc-by Advanced Electronic Materials 2025-01-01

Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival for prolonged cardiac arrest (CA) but carries significant risks and costs due to ECMO. Previous predictive models have been complex, incorporating both clinical data parameters obtained after CPR or ECMO initiation. This study aims compare a simpler clinical-only model with that includes pre-ECMO laboratory parameters, refine patient selection improve ECPR outcomes. Medical records between January 2012 2019 in our...

10.1038/s41598-025-87200-7 article EN cc-by-nc-nd Scientific Reports 2025-01-23

<sec> <title>BACKGROUND</title> Asthma is a common chronic condition in children, and severe complications can occur with infections like COVID-19 influenza. There limited research comparing the in-hospital outcomes of asthmatic children these infections. </sec> <title>OBJECTIVE</title> This study aims to compare from population-based perspective. <title>METHODS</title> retrospective used data 2020 United States (US) Nationwide Readmissions Database. Children 1-19 years old asthma admitted...

10.2196/preprints.73047 preprint EN cc-by 2025-02-24

Abstract In this study, multi-interfaced oxide-stacked resistive random-access memory (RRAM) with self-rectifying behaviors is presented. Self-rectifying characteristic, or called “nonlinearity,” essential on the stand-alone RRAM to be implemented in high density crossbar array without integrating additional selector. To modify nonlinearity for power efficiency, adding material interfaces considered as an approach tune geometric factors nanometer-scale microstructure. The trilayer device of...

10.1149/2162-8777/adc3c1 article EN publisher-specific-oa ECS Journal of Solid State Science and Technology 2025-03-21

10.1016/j.engappai.2017.06.021 article EN Engineering Applications of Artificial Intelligence 2017-08-10

Protection of small interfering RNA (siRNA) against degradation and targeted delivery across the plasma endosomal membranes to final site interference (RNAi) are major aims for development siRNA therapeutics. Targeting folate receptor (FR)-expressing tumors, we optimized polyplexes by coformulating a folate-PEG-oligoaminoamide (for surface shielding targeting) with one three lipo-oligoaminoamides (optionally tyrosine-modified, optimizing stability size) generate ∼100 nm lipopolyplexes...

10.1021/acs.bioconjchem.7b00383 article EN Bioconjugate Chemistry 2017-08-03

Aim: A thermosensitive injectable hydrogel composed of nanocomplexes doxorubicin and hyaluronic acid (HA) for the local treatment cancer diseases was developed characterized. Materials & methods: It found that addition a divalent metal ion Mg (MgCl2) required to properly form HA–doxorubicin nanocomplexes, which were mixed with Pluronic® F127 (BASF, Germany) hydrogels. Results: The DH700KMF-15 resulted in efficient growth inhibition C26 colon cells it selectively targeted lymphatic system by...

10.2217/nnm.14.211 article EN Nanomedicine 2014-12-05
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