A5101551468- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Retinal Diseases and Treatments
- Advanced Optical Imaging Technologies
- Immune cells in cancer
- Immunotherapy and Immune Responses
- Retinal Imaging and Analysis
- T-cell and B-cell Immunology
- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- Ocular and Laser Science Research
- Hydrocarbon exploration and reservoir analysis
- Laser Material Processing Techniques
- Adipokines, Inflammation, and Metabolic Diseases
- Genetics and Neurodevelopmental Disorders
- Chromosomal and Genetic Variations
- Immune Cell Function and Interaction
- Thyroid Disorders and Treatments
- Toxin Mechanisms and Immunotoxins
- Digital Holography and Microscopy
- Coenzyme Q10 studies and effects
Zhejiang University-University of Edinburgh Institute
2024
Beijing Normal University
2024
First Affiliated Hospital of Henan University of Science and Technology
2022
Ministry of Education of the People's Republic of China
2017-2021
China University of Geosciences (Beijing)
2017-2021
First Affiliated Hospital of Anhui Medical University
2018-2021
Anhui Medical University
2018-2021
Southern Medical University
2020
Qiqihar Medical University
2020
First Affiliated Hospital of Fujian Medical University
2020
Morphological changes of the vasculature system in patients with myopia have been observed by Doppler ultrasound and fundus fluorescein angiography (FFA); however, these studies limitations. provides low-resolution images which are mainly obtained from visualized large vessels, FFA is an invasive examination. Optic coherence tomography (OCT) a noninvasive, high-resolution measurement for vascular density. The purpose this study was to investigate change density myopic eyes using OCT...
Cockayne syndrome (CS) is a devastating progeria most often caused by mutations in the CSB gene encoding SWI/SNF family chromatin remodeling protein. Although all that cause CS are recessive, complete absence of protein does not CS. In addition, located beyond exon 5 and thought to generate only C-terminally truncated fragments. We now show domesticated PiggyBac-like transposon PGBD3, residing within intron gene, functions as an alternative 3' terminal exon. The alternatively spliced mRNA...
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by excessive fat accumulation in the form of triglycerides. The incidence NAFLD and hyperlipidemia, with their associated risks end-stage cardiovascular diseases, increasing rapidly. This study aimed to investigate effects scutellarin on experimental high-fat diet fed chronic stress rats, its possible mechanism. MATERIAL AND METHODS Sprague-Dawley rats were subjected for 12 weeks, administered orally 4 weeks...
Although studies have reported an increased risk for mood disorders in Hashimoto's thyroiditis (HT) patients even the euthyroid state, mechanisms involved remain unclear. Neuroinflammation may play a key role etiology of humans and behavioral disturbances rodents. Therefore, this study established HT model mice investigated whether itself was capable triggering neuroinflammation accompanied by emotional alterations.Experimental induced immunizing NOD with thyroglobulin adjuvant twice. Four...
Purpose: To evaluate the feasibility and safety of heads-up three-dimensional (3D) vision system for phacoemulsification intraocular lens (IOL) implantation surgery. Methods: In this prospective, randomized controlled study, 20 eyes with age-related cataract received IOL were randomly divided into "heads-up" 3D group conventional surgery group. Ocular surgical parameters such as time, pre postoperative best-corrected visual acuity (BCVA), corneal endothelial cells density recorded...
Background: M1 macrophage plays an important role in inflammatory reactions. In this study, potential anti-inflammatory effect of total flavonoids from Semen Astragali Complanate (Astragalus complanatus flavonoids, ACF) was assessed via Zebrafish acute inflammation model vivo and LPS-induced (M1 macrophage) vitro. Methods: The quality control ACF analyzed by HPLC. Anti-inflammatory on the injured zebrafish evaluated migration fluorescence labeled macrophages neutrophils, gene expression...
Background: Erigeron breviscapus (Vant.) Hand-Mazz. is a plant species in the Compositae family. More than ten types of compounds-such as flavonoids, caffeinate esters, and volatile oils-have been identified breviscapus; however, it remains unknown to which compounds are associated with clinical efficacy. In recent years, flavonoids phenolic acids have considered main effective components breviscapus. The metabolism mechanisms these vivo extensively studied improve our understanding drug....
Abstract As a highly efficient and energy-saving cavitation method, Venturi is widely used in many industrial fields. This study synchronously investigated the cavity behavior its corresponding wall static pressure characteristics channels with various divergence angles to research role of angle shape oscillation. Five rectangular different (4°, 6°, 8°, 10°, 12°) were tested at number (0.3–1.0). Based on dynamic behaviour gas–liquid interface, three shedding types identified: front (I),...
Hematopoietic stem cells (HSC) reside within specialized microenvironments that undergo dynamic changes throughout development and aging to support HSC function. However, the evolving cell-cell communication networks these niches remain largely unexplored. This study integrates single-cell RNA sequencing datasets systematically characterize niche interactome from ontogeny aging. We reconstructed atlases of at different developmental stages, revealing stage-specific cellular compositions...
To overcome the lack of availability fresh human whole blood for pyrogen detection, we explored feasibility utilizing cryopreserved pooled to detect responses pro-inflammatory cytokines IL-6 and IL-1β LPS. Whole was obtained from five donors incubated with The quantities were measured using ELISA, results compared among samples. After Dimethyl sulfoxide (DMSO) (10% v/v) stored 4 mo at –196℃, detection limits IL-6/IL-1β LPS 0.2/0.4 endotoxin units (EU)/ml, respectively, release increased in...
The purpose of this study was to investigate the therapeutic effects levothyroxine sodium combined with selenium treatment and single on patients chronic lymphocytic thyroiditis hypothyroidism analyze different regimens patients' thyroid function, mood, inflammatory factors, aim providing a reference for clinical treatment. subjects current were 138 (CLT) admitted our hospital from May 2016 September 2019 randomly divided into control group taking (LT4) LT4 treatment, 69 cases each. Patients...
Pneumocystis spp. are opportunistic fungal pathogens that closely associated with severe pneumonia and pulmonary complications in patients impaired immunity. In this study, the antigenic epitopes of gene encoding 55 kDa antigen fragment (p55), which may play an important role pneumonia, were analyzed. A containing tandem variants p55 was synthesized named (TAG). TAG's potential as a DNA vaccine assessed immunosuppressed rats. Immunization p55-TAG significantly reduced both pathogen burden...
Purpose To describe and to compare the clinical manifestation laboratory test results of herpetic anterior uveitis (HAU) caused by Herpes simplex virus (HSV) varicella-zoster (VZV).Methods A retrospective, observational study on patients diagnosed with HAU. Etiology, features, ocular complications, recurrences infection were evaluated as main parameters. The aqueous Interleukin-8 (IL-8) level was also measured assess intraocular inflammation.Results Thirty-two eyes (32 patients) involved....
Abstract Subarachnoid space (SAS) around optic nerve can be visible with swept-source optical coherence tomography (SS-OCT). However, the relevant factors for its visibility and width have not been reported. In this prospective study, 193 eyes high myopia were evaluated by SS-OCT. The relationship between age, gender, axial length, disc area, parapapillary atrophy (PPA) peripapillary choroidal thickness of SAS assessed. results showed that was observed in 125 (64.8%) 68 (35.2%) eyes....
HLA ‐A*11:120 has one nucleotide change from ‐A*11:01:01:01 where 295 T( ACC ) is changed to S( AGC ).