A5101909921- Liver Disease Diagnosis and Treatment
- Neonatal and fetal brain pathology
- Gastric Cancer Management and Outcomes
- Epilepsy research and treatment
- Infectious Encephalopathies and Encephalitis
- RNA regulation and disease
- Immune Response and Inflammation
- Esophageal and GI Pathology
- Metabolism and Genetic Disorders
- Autoimmune Neurological Disorders and Treatments
- Diet, Metabolism, and Disease
- Vagus Nerve Stimulation Research
- Burn Injury Management and Outcomes
- Biochemical effects in animals
- Inflammasome and immune disorders
- Fetal and Pediatric Neurological Disorders
- Infective Endocarditis Diagnosis and Management
- Autophagy in Disease and Therapy
- Epigenetics and DNA Methylation
- Infectious Diseases and Tuberculosis
- Respiratory Support and Mechanisms
- Pharmacological Effects and Toxicity Studies
- Hydrogen's biological and therapeutic effects
- Metabolism, Diabetes, and Cancer
- Infectious Aortic and Vascular Conditions
Guangxi University
2023
Daqing Oilfield General Hospital
2014-2021
Wuhan Children's Hospital
2020
Huazhong University of Science and Technology
2020
First Affiliated Hospital of Xi'an Jiaotong University
2020
Dalian Medical University
2018
Shenyang Center for Disease Control and Prevention
2017
Handan Polytechnic College
2008
Branched chain amino acids (BCAAs) are associated with the progression of obesity-related metabolic disorders, including type 2 diabetes and nonalcoholic fatty liver disease. However, whether BCAAs disrupt homeostasis hepatic glucose lipid metabolism remains unknown. In this study, we observed that supplementation significantly reduced high-fat (HF) diet–induced accumulation while increasing plasma levels promoting muscular renal accumulation. Further studies demonstrated increased...
Polycystic ovary syndrome (PCOS) is one of the most common causes infertility in child-bearing-age women. It characterized by ovulation dysfunction, polycystic ovaries, and hyperandrogenism. Inflammation likely to be a crucial contributor pathogenesis PCOS. However, association between inflammatory cytokines development PCOS has not been reported. To explore relationship PCOS, alterations serum proteins dehydroepiandrosterone (DHEA)-induced rats were screened protein array, concentration...
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by excessive fat accumulation in the form of triglycerides. The incidence NAFLD and hyperlipidemia, with their associated risks end-stage cardiovascular diseases, increasing rapidly. This study aimed to investigate effects scutellarin on experimental high-fat diet fed chronic stress rats, its possible mechanism. MATERIAL AND METHODS Sprague-Dawley rats were subjected for 12 weeks, administered orally 4 weeks...
Background Cervical cancer (CC) is the fourth leading cause of cancer-related death in women globally.While early screening has reduced mortality, tumor metastasis remains a significant concern, particularly developing countries. Recent studies have identified cuproptosis, copper-dependent cell mechanism, as potential factor progression. Long non-coding RNAs (lncRNAs) are key regulators This study investigates role cuproptosis-related lncRNA (CRL) CNNM3-DT CC, focusing on its impact LIAS...
Pneumonia is a disease causing serious inflammation and infection of the lungs accounts for >50,000 mortalities annually. The elderly are at an increased risk developing pneumonia. more in than any other age group due to community‑acquired pneumonia associated with aging. Interleukin‑1 receptor antagonist (IL‑1RA) anti‑inflammatory protein that counteracts destructive effects inflammatory proteins. Therefore, possible association between individuals reduced levels IL‑1RA was investigated...
Infections of prosthetic aortic grafts status post-acute dissection with Candida albicans (C. albicans) are rare. The gold standard treatment for graft infection is a combination surgical resection and lifelong antimicrobial drug therapy, however postoperative mortality rates remain high. Here we present 44-year-old man who presented 2 months fever, painful microembolic lesions localized to his right hypothenar eminence, conjunctival hyperemia, neural hearing loss, systolic murmur radiating...
2例学龄期患儿临床均表现为髓鞘少突胶质细胞糖蛋白（MOG）抗体病后出现抗N-甲基-D-天冬氨酸受体（NMDAR）脑炎，头颅磁共振成像示脱髓鞘病灶以幕上病灶为主，均为复发病程，最后诊断为儿童MOG抗体病合并抗NMDAR脑炎重叠综合征，予以免疫治疗后预后尚可。.
OBJECTIVE To determine the serum level and mRNA expression of type-1/type-2 cytokines T lymphocytes in spleens rats after thermal injury to investigate effects escharectomy during burn shock stage on IFN-gamma IL-4. METHODS One hundred sixty male Wistar were randomized into four groups. In group A, animals not subjected escharectomy. groups B, C D, skin allograft performed at 8, 24, 96 hours postburn (PB) respectively. At 4, 12, 48, 96, 120 168 PB, killed blood samples harvested. ELISA was...
ABSTRACT Ranavirus disease, caused by viruses within the genus (family Iridoviridae ), is considered a globally emerging infectious disease linked to mass mortality events in both wild and cultured ectothermic vertebrates. Surveillance work however limited Asia hence prevalence dynamics of remains poorly understood. To understand burden potential biotic abiotic drivers southern China region, we conducted systematic surveillance ranavirus across Guangxi Zhuang Autonomous region (GAR). For...
Objective To investigate the clinical efficacy and safety of oral high-dose methylprednisolone in treatment infantile spasms (IS). Methods The data 38 children with were analyzed retrospectively who treated administration methylprednisone Department Neurology, Wuhan Children's Hospital, Tongji Medical College, Huazhong University Science Technology from January 2016 to April 2017. Results ⑴ Twenty patients (52.6%) all seizure-free after 2 weeks treatment, 16 cases (42.1%) at end...