A5006968609- Bacterial Infections and Vaccines
- Robotics and Sensor-Based Localization
- Metabolomics and Mass Spectrometry Studies
- 3D Surveying and Cultural Heritage
- Osteoarthritis Treatment and Mechanisms
- Psychosocial Factors Impacting Youth
- Adipokines, Inflammation, and Metabolic Diseases
- Medical Imaging and Analysis
- Reproductive Biology and Fertility
- Educational Reforms and Innovations
- Hepatitis B Virus Studies
- 3D Shape Modeling and Analysis
- Fire effects on concrete materials
- Lipoproteins and Cardiovascular Health
- Infectious Diseases and Tuberculosis
- Paleopathology and ancient diseases
- COVID-19 and healthcare impacts
- Corrosion Behavior and Inhibition
- Traditional Chinese Medicine Analysis
- Concrete Corrosion and Durability
- Remote Sensing and LiDAR Applications
- Artificial Intelligence in Healthcare
- Neonatal Respiratory Health Research
- MicroRNA in disease regulation
- Inflammatory mediators and NSAID effects
Obstetrics and Gynecology Hospital of Fudan University
2020-2025
Fujian Medical University
2020-2024
First Affiliated Hospital of Fujian Medical University
2020-2024
Chongqing University
2023
Huazhong University of Science and Technology
2020-2021
University of Benin
2020
Fraunhofer Institute for Production Technology IPT
2016
PNO1, a key promoter of oncogenesis, is often characterized by its aberrant expression in both colorectal and esophageal cancers, markedly accelerating their progression. Nonetheless, the role PNO1 ovarian cancer underlying mechanisms remain unexplored comprehensively. In addition to abnormal tissues The Cancer Genome Atlas (TCGA) database, clinical data examinations indicated strong association with lower survival rates among patients. Considering crucial AKT signaling pathway, we...
COVID-19 caused by the coronavirus SARS-CoV-2 has resulted in a global pandemic. Considering some patients with rapidly develop respiratory distress and hypoxemia, early assessment of prognosis for is important, yet there currently lack research on comprehensive multi-marker approach disease assessment. Here, we utilized large sample hospitalized individuals to systematically compare clinical characteristics at admission developed nomogram model that was used predict prognosis. In all cases,...
Osteoarthritis (OA) is the most common joint disease in world, characterized by pain and loss of function, which has led to a serious reduction quality patients’ lives. In this work, ultrahigh performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UPLC-QToF/MS) conjunction multivariate pattern recognition methods an univariate statistical analysis scheme were applied explore serum metabolic signatures within OA group ( n = 31), HC (healthy...
Objective We aimed to investigate the association and diagnostic value of monocyte distribution width (MDW) for chronic hepatitis B (CHB), liver cirrhosis (LC), hepatocellular carcinoma (HCC). Methods MDW levels were measured in 483 individuals (103 CHB, 77 LC, 153 HCC, 150 controls). was detected using UniCel Dx900 specific cell volume parameters volumes. Results Our findings revealed a dynamic upward change across different stages disease, from CHB LC HCC. In highest among HBeAg-positive...
Abstract Background Increased evidence has reported the association of genetic polymorphisms Apolipoprotein E (APOE) with serum lipids. However, few studies have explored combined effects APOE, gender, and age. Methods A total 1,419 middle-aged elderly subjects were randomly selected studied. The APOE genotypes lipids detected. age on preliminarily observed in general. then divided into group (40–64 years old) (≥ 65 old), for both males females, to explore Finally, a multivariate logistic...
Background Anti- N -methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common type of autoimmune encephalitis. Early recognition and treatment, especially distinguishing from viral (VE) in early stages, are crucial for outcomes patients with anti-NMDAR Compared plasma microRNAs (miRNAs), exosomal miRNAs more abundant not easy to degrade. Moreover, exosomes can pass through blood–brain barrier. This study aimed explore clinical value serum differential diagnosis VE. Method...
摘要: 基于点云局部特征描述的三维目标识别是机器人视觉领域一个具有重要研究价值且富有挑战性的研究方向。尽管目前已有大量三维特征描述子的相关研究工作,但它们大多数采用浮点数,对计算和存储的开销很大,并且鉴别力较弱,鲁棒性不强。鉴于此,从点对特征出发,提出一种鉴别力高,鲁棒性强,结构紧凑,计算迅速的高性能点云局部描述算法—二进制点对特征直方图(Binarized histogram of point pair features,B-HPPF)。对模型进行降采样,根据点位置与点法线信息,计算局部邻域中点对的七个特征;利用其将局部点对集划分为若干区域,并对每一区域进行信息提取;通过轮换比较各信息量的大小将特征进行二进制编码;将每一区域的二进制子特征串联组合生成最终的二进制描述子B-HPPF。所提出的B-HPPF描述子在多个公开数据集上进行测试,并与经典的描述算法进行对比,结果表明,所提出的方法在鉴别力、鲁棒性、紧凑性和计算效率等方面获得了优越的综合性能。此外,B-HPPF的实用性也在目标识别数据集上得以进一步验证。
Abstract Objective To investigate the protective effect and mechanism of hyperin on hydrogen peroxide (H2O2)-induced injury granulosa cells in mice. Methods Adult female BALB/c mice were randomly divided into control group, POI model group treatment group. The primary ovarian extracted, cultured vitro, exposed to H 2 O establish oxidative damage cells. added with different concentration (0µg/l, 5µg/l, 10µg/l, 25µg/l, 50µg/l, 75µg/l respectively); observed proliferation under concentration....
Purpose: To examine the effect of mangiferin on insulin resistance (IR) in a rat polycystic ovary syndrome (PCOS) model.Methods: The PCOS model was established via subcutaneous injection 6 mg/kg dehydroepiandrosterone (DHEA), and orally administered. Body ovarian weights were recorded. Serum levels glucose, insulin, related inflammatory cytokines evaluated by quantitative real-time polymerase chain reaction (qRT-PCR) enzyme-linked immunosorbent assay, while expression key proteins analyzed...
The early differential diagnosis between bacterial meningitis (BM) and tuberculous (TBM) or cryptococcal (CM) remains a significant clinical challenge. Neutrophil Gelatinase-Associated Lipocalin (NGAL) has been reported as novel inflammatory biomarker in the stages of infection. This study aimed to investigate whether cerebrospinal fluid (CSF) NGAL can serve potential for distinguishing BM TBM CM.We prospectively enrolled patients with suspected CNS infections at admission divided them into...
Abstract Background The early differential diagnosis between bacterial meningitis (BM) and tuberculous (TBM) or cryptococcal (CM) is still an important clinical challenge. Neutrophil Gelatinase-Associated Lipocalin (NGAL) had been reported as a novel inflammatory biomarker in stage of infection. This study aimed to explore whether cerebrospinal fluid (CSF) NGAL potential for distinguishing BM TBM CM. Methods Prospectively enrolled the patients with suspected CNS infections at admission...
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Gadd45β have a regulatory role in cellular inflammation, proliferation and migration. However, the of synovial inflammation osteoarthritis (OA) remains to be explored. This study aimed ascertain whether is involved OA inflammation.
An overall workflow based on gas chromatography-mass spectrometry (GC-MS) was established for the analysis of serum amino acid profile between urolithiasis patients (n=80, age (46.82±13.39) years) and healthy controls (n=37, (43.46±12.79) years). The raw data from GC-MS were processed by multivariate statistical methods to build model. Following this, student's t-test logistic regression performed receiver operator characteristic (ROC) curve plotted identify potential biomarkers. Good...
Background: It is difficult for early differential diagnosis between bacterial meningitis (BM) and tuberculous (TBM) or cryptococcal (CM).Therefore, a novel reliable biomarker urgently required. Neutrophil Gelatinase-Associated Lipocalin (NGAL) have been reported as differentiating the viral infections, however, whether CSF NGAL potential distinguishing BM TBM CM are not reported.Methods: Prospectively enrolled patients with suspected CNS infections at admission, divided them into three case...
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In this work, we propose a robust pipeline to create vectorized models from LiDAR point clouds without the assumption of watertight polygonal surfaces. The core idea behind our method is combining hierarchical 2D projection with pairwise intersections clipped planes precisely hypothesize faces an object inside and outside while enhancing robustness different scenes. Moreover, generate concise polygon meshes efficiently, Adaptive K-means++ (AKM++) used smooth rasterized height map followed by...
Abstract Background: Urinary stone disease (USD) is a common with high prevalence, recurrence rate and lack of effective diagnostic biomarkers. Methods: To explore the potential biomarkers for USD early diagnosis, serum urinary amino acid (AA) profiles 74 patients were compared 35 healthy controls (HC) via gas chromatography coupled mass spectrometry (GC-MS). Results: Based on AA analyzed by metabolomic strategy, group 5 differentially expressed AAs including Ser, Glu, Asp, Ile Gly 7...