A5101684421- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Tropical and Extratropical Cyclones Research
- Methane Hydrates and Related Phenomena
- Ocean Waves and Remote Sensing
- Polysaccharides and Plant Cell Walls
- Probiotics and Fermented Foods
- Plant-Microbe Interactions and Immunity
- Ginseng Biological Effects and Applications
- Seaweed-derived Bioactive Compounds
- Plant tissue culture and regeneration
- Oral microbiology and periodontitis research
- Magnetic properties of thin films
- Flood Risk Assessment and Management
- Chinese history and philosophy
- Viral gastroenteritis research and epidemiology
- Echinoderm biology and ecology
- Plant Molecular Biology Research
- Pharmacological Effects of Natural Compounds
- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- Mesenchymal stem cell research
- Identification and Quantification in Food
- Virus-based gene therapy research
- Remote Sensing and Land Use
Max Planck Institute for Marine Microbiology
2023-2024
Shanghai Jiao Tong University
2010-2024
Shanghai Institute of Materia Medica
2014-2023
Chinese Academy of Sciences
2014-2023
First Affiliated Hospital of Fujian Medical University
2023
Fujian Medical University
2023
East China University of Science and Technology
2023
Shandong Marine Resource and Environment Research Institute
2018-2022
Shanghai Children's Hospital
2020-2022
Shanghai Ninth People's Hospital
2010-2020
<i>Panax notoginseng</i> (Sanqi) is a cardiovascular herb containing ginsenosides that are believed to be responsible for the therapeutic effects of Sanqi. The aim this study was evaluate rat exposure after oral administration Sanqi extract and identify key factors affecting their absorption disposition. Ginsenosides were administered rats, either in form or as pure chemicals. Ra<sub>3</sub>, Rb<sub>1</sub>, Rd, Re, Rg<sub>1</sub>, notoginsenoside R<sub>1</sub> major saponins present herbal...
Abstract Background Macroalgal epiphytic microbial communities constitute a rich resource for novel enzymes and compounds, but studies so far largely focused on tag-based diversity analyses or limited metagenome sequencing of single macroalgal species. Results We sampled bacteria from specimens Ulva sp. (green algae), Saccharina (brown Grateloupia Gelidium (both red algae) together with seawater sediment controls coastal reef in Weihai, China, during all seasons. Using 16S rRNA amplicon...
Abstract Background Marine microalgae (phytoplankton) mediate almost half of the worldwide photosynthetic carbon dioxide fixation and therefore play a pivotal role in global cycling, most prominently during massive phytoplankton blooms. Phytoplankton biomass consists considerable proportions polysaccharides, substantial parts which are rapidly remineralized by heterotrophic bacteria. We analyzed diversity, activity, functional potential such polysaccharide-degrading bacteria different size...
Ginsenosides are bioactive saponins derived from Panax notoginseng roots (Sanqi) and ginseng. Here, the molecular mechanisms governing differential pharmacokinetics of 20(S)-protopanaxatriol-type ginsenoside Rg1 , Re notoginsenoside R1 20(S)-protopanaxadiol-type ginsenosides Rb1, Rc Rd were elucidated.Interactions with human rat hepatobiliary transporters characterized at cellular vesicular levels. A rifampin-based inhibition study in rats evaluated vivo role organic anion-transporting...
Phytoplankton blooms fuel marine food webs with labile dissolved carbon and also lead to the formation of particulate organic matter composed living dead algal cells. These particles contribute sequestration are sites intense algal-bacterial interactions, providing diverse niches for microbes thrive. We analyzed 16S 18S ribosomal RNA gene amplicon sequences obtained from 51 time points metaproteomes 3 during a spring phytoplankton bloom in shallow location (6-10 m depth) North Sea....
This study compared the osteogenic potential of bone marrow mesenchymal stem cells (BMSCs) iliac and alveolar origins (I-BMSCs Al-BMSCs, respectively), which were transplanted in combination with β tricalcium phosphate (β-TCP) peri-implant defects to investigate osseointegration between dental implants tissue-engineered dogs. Specifically, I-BMSCs Al-BMSCs cultured, characterized, seeded on β-TCP subjected immunoblotting analyses alkaline phosphatase activity assays. Subsequently, these...
A Gram-stain-negative, facultatively anaerobic, orange-pigmented bacterium, designated HQYD1T, was isolated from a sea squirt (Styelaclava) and characterized using polyphasic approach. Morphologically, strain HQYD1T exhibited rods with gliding motility. This novel isolate grew optimally at 28 °C in the presence of 2-3 % (w/v) NaCl. The 16S rRNA gene sequence most similar to [Saccharicrinis] marinus Y11T (96.3 %), followed by Saccharicinis fermentans DSM 9555T (93.8 %). dominant fatty acids...
Abstract Laminarin, a β(1,3)‐glucan, serves as storage polysaccharide in marine microalgae such diatoms. Its abundance, water solubility and simple structure make it an appealing substrate for bacteria. Consequently, many bacteria have evolved strategies to scavenge decompose laminarin, employing carbohydrate‐binding modules (CBMs) crucial components. In this study, we characterized two previously unassigned domains laminarin‐binding CBMs multimodular proteins from the bacterium...
The study of genomic divergence between humans and primates may provide insight into the origins human beings genetic basis unique traits diseases. Chromosome 21 is smallest chromosome in genome, some its regions have been implicated mental retardation other In this study, we sequenced coding regulatory 127 known genes on DNA samples from chimpanzees a part corresponding orangutan, gorilla, macaque. Overall, 3,003 nucleotide differences chimpanzee were identified over ≈400 kb. coding,...
A Gram-stain-negative, facultatively anaerobic coccobacilli approximately 0.4-0.5×0.5-1.1 µm, non-motile, orange-pigmented bacterial strain, designated am2T, was isolated from the coastal area of Weihai, PR China (121° 57' E, 37° 29' N). The temperature, pH and NaCl ranges for growth were 4-40 °C, 6.5-8.5 0.0-6.0 % (w/v) NaCl. results phylogenetic analyses based on 16S rRNA gene sequences revealed that am2T phylogenetically related to members genus Algoriphagus closely boritolerans,...
A Gram-stain-negative and facultatively anaerobic bacterium, SY21(T), was isolated from marine sediments of the coastal area in Weihai, China (122° 0' 37" E 37° 31' 33" N). Cells strain SY21(T) were 0.3-0.5 μm wide 1.5-2.5 long, catalase- oxidase-positive. Colonies on 2216E agar transparent, beige- to pale-brown-pigmented, approximately 0.5 mm diameter. Growth occurred optimally at 33-37 °C, pH 7.0-7.5 presence 2-3% (w/v) NaCl. Phylogenetic analysis 16S rRNA gene indicated that a member...
With 2 figures and 1 table Abstract Brown spot (BS) caused by Alternaria alternata is one of the most destructive foliar diseases affecting tobacco ( Nicotiana tabacum L.) production quality in China. Breeding BS‐resistant cultivars difficult because resistance has proved to be quantitatively inherited. To facilitate marker‐assisted selection, we carried out a study mapping quantitative trait loci (QTLs) for BS resistance. We developed an F population consisting 213 individuals from cross...
A protease-producing bacterial strain, 13-12T, was isolated from the ocean sediment of Laizhou Bay, PR China and systematically studied. The bacterium Gram-stain negative, non spore-forming rods, which were motile with two flagella. It positive for oxidase, hydrolysis starch, agar gelatin, nitrate reduction. negative catalase, esterase degradation CM-cellulose. Optimum growth observed at 28 °C, pH 6.5-7.0 in presence 2-3 % (w/v) NaCl. Phylogenetic analysis 16S rRNA gene, whole genome data,...
A yellow-pigmented, Gram-stain-negative and facultatively anaerobic bacterium, designated FB218 T , was isolated from a sediment sample collected sea cucumber culture pond in Rongcheng, China (36° 54′ 36″ N 122° 14′ 34″ E). Cells of strain were slender, gliding, catalase-positive oxidase-negative. Optimal growth occurred at 30 °C, pH 6.5–7.0 medium containing 2–3 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequences showed that belonged to the genus Carboxylicivirga family...
Many marine bacteria are difficult to culture because they dormant, rare or found in low-abundances. Enrichment culturing has been widely tested as an important strategy isolate dormant microbes. However, many more mechanisms remain uncertain. Here, based on 16S rRNA gene high-throughput sequencing and metabolomics technology, it was that the short-chain fatty acids (SCFAs) metabolites were significantly correlated with uncultured bacterial groups during enrichment cultures. A pure analysis...
A facultatively anaerobic and Gram-negative bacterium, designated strain PLHSC7-2T, was isolated from the gut of sea cucumber Apostichopusjaponicus that had been collected coastal area Yantai, China. The cells were rod-shaped motile by means polar flagella. novel isolate grew optimally at 28-30 °C, in presence 2.0-3.0 % (w/v) NaCl pH 7.0-7.5. sole respiratory quinone Q-8 major fatty acids summed feature 3 (C16 : 1ω7c and/or C16 1ω6c), 0 C17 0. predominant lipids phosphatidylethanolamine,...
The ultrafine grain size with a narrow distribution is critical issue for the development of L10-FePt thin films as ultrahigh density magnetic recording media. In this study, we succeeded in reducing both and ordered domain simultaneously improving uniformity by annealing disordered FePt at high pressure 1 GPa. This attributed to fact that promotes nucleation L10 domains inhibits growth grains during ordering transition.
A yellow-pigmented bacterial strain (JR1T) isolated from a sediment sample was subjected to taxonomic study, based on phenotypic, genetic and physiological characterization. Here, we describe the cultivation characteristics of JR1T, novel member genus Carboxylicivirga in family Marinilabiliaceae. Cells JR1T were rod-shaped, Gram-stain-negative, non-motile facultatively anaerobic. The temperature range for growth 15-42 °C (optimum, 33 °C) pH 6.0-8.5 7.0-7.5). Growth occurred presence 0.0-10.0...
A Gram-stain-negative, rod-shaped and facultatively anaerobic strain, designated CG51T, was isolated from marine sediment collected a coastal area in Weihai, PR China. Strain CG51T grew at 4-37 °C (optimum, 28-30 °C), with 1.0-6.0 % (w/v) NaCl (2.0-3.0 %) pH 6.0-8.5 (pH 7.0-7.5). The predominant fatty acids were iso-C15 : 0, anteiso-C15 0 iso-C14 0. Major polar lipids included an unidentified lipid phospholipid. respiratory quinone MK-7 the genomic DNA G+C content 35.9 mol%. results of...