A5024154237- HIV/AIDS Research and Interventions
- Reproductive tract infections research
- Photodynamic Therapy Research Studies
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Hematopoietic Stem Cell Transplantation
- Adolescent Sexual and Reproductive Health
- Periodontal Regeneration and Treatments
- Blood Pressure and Hypertension Studies
- Antimicrobial Peptides and Activities
- Advanced Drug Delivery Systems
- Peptidase Inhibition and Analysis
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cancer Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Youth Development and Social Support
- Orthopedic Infections and Treatments
- Brain Metastases and Treatment
- Maternal and Neonatal Healthcare
- Cytomegalovirus and herpesvirus research
- HIV/AIDS oral health manifestations
- Immune Cell Function and Interaction
- Corneal Surgery and Treatments
- Family Caregiving in Mental Illness
- Testicular diseases and treatments
University of Minho
2018-2024
Instituto Geográfico Nacional
2022
Secretaria de Planejamento e Gestão
2022
Universidade Estadual de Feira de Santana
2022
Sistema (Russia)
2022
Universidade do Porto
2014-2016
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2014-2016
Administração Regional de Saúde de Lisboa e Vale do Tejo
2013
Universidad Nacional Experimental Simón Rodríguez
2004
Abstract Objectives This study aimed to improve the performance and mode of administration a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), association with dextrin-based hydrogel, DEXGEL, achieve an injectable moldable device named DEXGEL Bone. Methods Twelve participants requiring pre-molar tooth extraction implant placement were enrolled in this study. BL® granules (250–500 µm) administered 6 randomized whereas other received After months, biopsy...
Abstract A local drug delivery system that attempts to find a suitable balance between antimicrobial and regenerative actions was developed for osteomyelitis treatment (OM). This combines the angiogenic immunomodulatory peptide LLKKK18 (LL18) vancomycin hydrochloride (VH), loaded into an injectable oxidized dextrin (ODEX)‐based hydrogel (HG). In vitro cytotoxicity analyzed in MC3T3‐E1 pre‐osteoblasts erythrocytes. The kinetics of LL18 release studied. Antimicrobial activity assessed against...
Introdução: A problemática dos hiperfrequentadores nos Cuidados de Saúde Primários tem impacto humano, económico e social não desprezível. O objetivo deste trabalho é descrever as características sociodemográficas patológicas utentes hiperfrequentadores. Material Métodos: Foi efetuado um estudo transversal descritivo, com componente analítica, da população inscrita nas listas seis médicos família do Centro Senhora Hora, entre Janeiro 2007 Dezembro 2009. Obtiveram-se dados sociodemográficos...
In this work, an expedite synthesis was developed for a self-assembled micelle carrier the antimicrobial peptide LL18. Covalent one-pot functionalization of dextrin with succinylated vitamin D3 and succinic anhydride produced amphiphilic material that undergoes self-assembly into micelles in aqueous medium. Succinylated dextrin-vitamin were efficiently loaded LL18 by electrostatic hydrophobic interactions. Remarkably, LL18-loaded formulation dramatically improves antibacterial activity free against
Regeneration of severe bone defects remains a challenge. A formulation synthetic glass-reinforced hydroxyapatite substitute, Bonelike® Poro (BL®P), 250 - 500 µm-diameter, with dextrin-based hydrogel (HG), further loaded human dental pulp stem cells (hDPSCs) osteogenic differentiation ability, was tested for the management critical-sized in an ovine model. Morphology, calcium release, and mechanical strength HG + BL®P were analyzed. Then, BL®P, 106 hDPSCs-loaded implanted 14 mm-diameter...
CERVICAL CYTOLOGY AND THE USE OF LUBRICANTS: AN EVIDENCE BASED REVIEW Objectives: To review recent evidence on the effect of lubricant cytological result obtained from cervical smears. Data sources: Evidence-based medicine websites and Índex de Revistas Médicas Portuguesas. Methods: A search for articles using MeSH terms vaginal smears lubricants published between January 2000 2011 was conducted. Citations were also searched. The Oxford Centre Medicine - Levels Evidence used to assess...