Pedro M. Castro

ORCID: 0000-0001-7164-8005
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Advanced Drug Delivery Systems
  • Drug Solubulity and Delivery Systems
  • Proteins in Food Systems
  • Nanocomposite Films for Food Packaging
  • Polysaccharides and Plant Cell Walls
  • Phytochemicals and Antioxidant Activities
  • Advanced Cellulose Research Studies
  • Advancements in Transdermal Drug Delivery
  • Protein purification and stability
  • Protein Hydrolysis and Bioactive Peptides
  • RNA Interference and Gene Delivery
  • Nanoparticles: synthesis and applications
  • Oral microbiology and periodontitis research
  • biodegradable polymer synthesis and properties
  • Infant Nutrition and Health
  • Microencapsulation and Drying Processes
  • Inhalation and Respiratory Drug Delivery
  • Marine and fisheries research
  • Photodynamic Therapy Research Studies
  • Microbial Inactivation Methods
  • Coral and Marine Ecosystems Studies
  • Urban Development and Societal Issues
  • Polysaccharides Composition and Applications
  • Antimicrobial Peptides and Activities
  • Antioxidant Activity and Oxidative Stress

Universidade Católica Portuguesa
2009-2024

Cooperativa de Ensino Superior Politécnico e Universitário
2015-2019

Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde
2015-2019

Companhia Energética de Minas Gerais (Brazil)
2019

Istituto Nanoscienze
2019

University of Bologna
2019

Universidade do Porto
2018

Nowadays, bioactive peptides are used for therapeutic applications and the selection of a carrier to deliver them is very important increase efficiency, absorption, release, bioavailability consumer acceptance. The aim this study was develop characterize chitosan-based films loaded with chitosan microparticles containing peptide (sequence: KGYGGVSLPEW) antihypertensive properties. Films were prepared by solvent casting method, while ionic gelation. final optimized exhibited mean diameter 2.5...

10.3390/ph12010032 article EN cc-by Pharmaceuticals 2019-02-20

In times of pandemic and when sustainability is in vogue, the use byproducts, such as fiber-rich tomato can be an asset. There are still no studies on impact extraction methodologies gastrointestinal tract action bioactive properties. Thus, this study used a solid fraction obtained after conventional method (SFCONV) ohmic (SFOH) to analyze effect compounds (BC) bioactivities. Results showed that SFOH presents higher total fiber than SFCONV samples, 62.47 ± 1.24–59.06 0.67 g/100 g DW,...

10.3390/foods10030554 article EN cc-by Foods 2021-03-07

Poor aqueous solubility, stability and bioavailability of interesting bioactive compounds is a challenge in the development formulations. Cellulose nanostructures are promising sustainable carriers with unique features that may be used enabling delivery strategies. In this work, cellulose nanocrystals (CNC) nanofibers were investigated as for curcumin, model liposoluble compound. Nanocellulose modification surfactant cetyltrimethylammonium bromide (CTAB), tannic acid decylamine (TADA), by...

10.3390/pharmaceutics15030981 article EN cc-by Pharmaceutics 2023-03-18

Background: Biological molecules such as therapeutic proteins and peptides have provided ample opportunities for further improvements in health wellbeing. However, biomacromolecules face stability challenges regarding premature processing digestion, whenever any enteric delivery route is considered. Hence, oral guar films entrapping peptide-containing chitosan microparticles been developed a new system to carry protect relaxing peptides. Results: The composite were characterized...

10.3390/app11219849 article EN cc-by Applied Sciences 2021-10-21

Curcumin is a natural phenolic compound with important biological functions. Despite its demonstrated efficacy in vitro, curcumin activities vivo are dependent on bioaccessibility and bioavailability, which have been highlighted as crucial challenge. Cetyltrimethylammonium bromide-modified cellulose nanocrystals (CNC-CTAB) shown to be effective encapsulation, they the potential enhance outcomes. This study evaluated effects of encapsulated within CNC-CTAB structures, namely antioxidant,...

10.3390/ph16121737 article EN cc-by Pharmaceuticals 2023-12-17

O objetivo deste estudo é demonstrar que a utilização generalizada das Redes Protegidas viável em todas situações encontradas nos meios urbanos.

10.5380/revsbau.v2i1.66259 article PT cc-by-nc Revista da Sociedade Brasileira de Arborização Urbana 2019-04-30

O objetivo do presente trabalho foi avaliar a eficiência da estimação altura de mudas Tibouchina granulosa em função diâmetro coleto, sob diferentes composições substrato, empregando Redes Neurais Artificiais (RNA). Foram selecionadas 72 produzidas via tubetes para repicagem baldes 25 litros. Adotou-se delineamento experimental inteiramente casualizado, com três repetições, sendo os tratamentos constituídos por quatro substrato. Cada unidade composta seis mudas. Aos 13 meses idade foram...

10.5380/revsbau.v9i1.66600 article PT cc-by-nc Revista da Sociedade Brasileira de Arborização Urbana 2019-04-30
Coming Soon ...