A5103039385- Testicular diseases and treatments
- Sarcoma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Pediatric Urology and Nephrology Studies
- Foreign Body Medical Cases
- Gastrointestinal disorders and treatments
- Ureteral procedures and complications
- Urologic and reproductive health conditions
- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Curcumin's Biomedical Applications
- Bone Tumor Diagnosis and Treatments
- Lipid metabolism and biosynthesis
- Radiomics and Machine Learning in Medical Imaging
- Hippo pathway signaling and YAP/TAZ
- Restraint-Related Deaths
- Airway Management and Intubation Techniques
- Gastrointestinal Tumor Research and Treatment
- Adrenal and Paraganglionic Tumors
- Metabolism, Diabetes, and Cancer
- Sperm and Testicular Function
- Minimally Invasive Surgical Techniques
- Epilepsy research and treatment
- Cancer Mechanisms and Therapy
- Food Chemistry and Fat Analysis
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2015-2025
Wenzhou Medical University
2015-2025
State Council of the People's Republic of China
2020
South China Agricultural University
2020
Wenzhou University
2020
Qilu Hospital of Shandong University
2016-2018
Pediatric Oncology Group
2017
Jinan University
2015
Objective To investigate the effect of Rapamycin on proliferation and autophagy in human neuroblastoma (NB) cell lines to elucidate possible mechanism. Methods NB cells were treated with different concentrations Rapamycin. Cell counting kit-8 (CCK-8) was used measure proliferation, flow cytometry (FCM) analyze cycle. EM observe morphological changes. Western blotting (WB) performed detect expression Beclin-1, LC3-I/II, P62, mammalian target (mTOR), p-mTOR. Results inhibited spread a dose-...
Meckel diverticulum is the most prevalent congenital abnormality of gastrointestinal tract in children. The aim this study was to review and analyze clinical data on diagnosis management pediatric patients. records 102 patients (<14 years old) who underwent surgery for at our institute between 2001 2015 were reviewed. Clinical, imaging, laboratory, surgical, pathological recorded. series comprised 65 males 37 females with a median age 5.6 years. Lower bleeding frequently identified...
Ceramide and lecithin formed oleogels with different behaviors. Results indicated that they co-assembled at approximately equal molar ratio, the redundant gelator in other ratios self-sorted to combine fibers.
A proposed novel mechanism of anticancer activity curcumin micelles through redox equilibrium in gastric cancer.
Children with foreign bodies (FBs) in the lower urinary tract have rarely been reported, and their management remains challenging. This study aimed to describe characteristics treatment of FBs children's tract.We retrospectively analyzed clinical data on that were removed our hospital from August 2017 2022, including demographics, location, symptoms, imaging examinations, treatment.Four male patients enrolled, whose ages ranged 9 13 years, a mean age 11 years. The course disease 3 h 2 weeks....
Background: The true incidence of gonadal germ cell tumors (GCTs) in children is unknown. Few studies have been published concerning about pediatric GCTs. aim this study to review and analyze clinical data on the diagnosis management GCTs children. Methods: Between 2005 2015, 127 patients (<14 years old) with admitted our institute were reviewed. Clinical features, imaging laboratory studies, surgical approaches, as well pathological diagnoses recorded. Results: series comprised 53 males...
Gastric cancer (GC) is one of the most common malignant tumors in world. It fourth and has second highest mortality rate globally. Metastasis an important feature gastric cause death. Exploring mechanism underlying metastasis searching for new drug targets become focus several studies. Traditional Chinese medicine may show promise treatment cancer. In this review, we report recent progress research on anti-metastasis activity medicine, to facilitate clinical development treatments
Cystoscopic technique is the current common method of retrieving double J ureteral stent in most pediatric urological centers. In this study, we evaluated feasibility and efficacy a novel noncystoscopic to remove retained stents patients. We reviewed all medical records from total 102 patients who were treated our hospital between January 2013 December 2016 into ureter. The divided 2 groups based on different surgical options: cystoscopic group group. surgery time (including for instrument...
Aim Foreign body (FB) injuries represent a severe public health problem during childhood. The aim of this study was to report our experience with patients due FB ingestion and insertion who were treated surgically at institution. Methods A total 78 paediatric hospitalised for retrospectively reviewed. Results series composed 27 males 51 females, median age 3.6 years. cases included 35 43 insertion, including 40 vaginal 2 rectal 1 case urethra insertion. Intestinal perforation ( n = 26) more...
Minimally invasive cholecystolithotomy is recently popularized treatment that may offer advantages over laparoscopic cholecystectomy, especially in China. However, there are few reports concerning the use of this technique pediatric population. This report describes our initial experience with minimally using laparoscopy combined choledochoscopy to treat cholecystolithiasis children.A retrospective review 23 patients who underwent from January 2009 December 2015 was performed.The operations...
Laparoscopic surgery is the current accepted approach in most pediatric surgical centers. In an attempt to further minimize trauma and improve cosmetic outcome, new techniques with a single incision through umbilicus have been proposed we believe they will become standard choices for surgery. This report describes our initial experience transumbilical single-incision laparoscopic (TSILS) children conventional instruments.A retrospective review of 82 patients who underwent TSILS instruments...
Abstract Objectives Restoring a functional beta‐cell mass is fundamental goal in treating diabetes. A complex signalling pathway network coordinates the regulation of proliferation, although role for ERK 5 this has not been reported. This question was addressed study. Materials and methods We studied activation extracellular‐signal‐regulated kinase (ERK5) pregnant mice, well‐known mouse model increased proliferation. specific inhibitor activation, BIX 02189, intraperitoneally injected into...
Testicular torsion is a urology urgent disease which causes testicular injury and potential sterility. In this study, we explored the protective influence of rosiglitazone on ischaemia–reperfusion damage. There were 28 male Sprague Dawley rats in total, assigned randomly to four groups. Group A was blank control one; group B C D antagonist one. The testicles counter-rotated after 2 hr then underwent orchiectomy 24 later. We found that tissue structure seriously damaged groups D. However, had...