Jisheng Wang

ORCID: 0000-0003-2949-3825
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Research Areas
  • Sexual function and dysfunction studies
  • Plant Virus Research Studies
  • Chromosomal and Genetic Variations
  • Plant tissue culture and regeneration
  • Hormonal and reproductive studies
  • Urinary Bladder and Prostate Research
  • Sperm and Testicular Function
  • Healthcare and Venom Research
  • Sexuality, Behavior, and Technology
  • Network Security and Intrusion Detection
  • Reproductive Biology and Fertility
  • Pelvic floor disorders treatments
  • Cancer-related molecular mechanisms research
  • Migraine and Headache Studies
  • Genital Health and Disease
  • Glioma Diagnosis and Treatment
  • Prostate Cancer Diagnosis and Treatment
  • Invertebrate Immune Response Mechanisms
  • MicroRNA in disease regulation
  • Acupuncture Treatment Research Studies
  • Pharmacological Effects of Natural Compounds
  • Lung Cancer Treatments and Mutations
  • Cardiac Ischemia and Reperfusion
  • Medicinal Plant Pharmacodynamics Research
  • Reproductive System and Pregnancy

Mianyang Third People's Hospital
2012-2025

Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2016-2024

Wenzhou Medical University
2012-2024

Wannan Medical College
2024

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2017-2024

Nanjing Agricultural University
2022-2024

First Affiliated Hospital of Nanchang University
2024

Nanchang University
2005-2024

China Academy of Transportation Sciences
2023

Second Affiliated Hospital of Nanchang University
2023

// Nan Ji 1, 6, * , Danhui Weng 3, Cang Liu 4 Zheng Gu 5 Shizhang Chen 2 Ying Guo Zhong Fan Xiao Wang Jianfei Yanyan Zhao Jianfeng Zhou 3 Jisheng 6 Ding Ma Ning Li 1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, P.R. China YouAn Tongji Hospital Affiliated with College Huazhong University Science and Technology, Wuhan, Friendship Chao-Yang Key Laboratory Brian Tumor, These authors have contributed equally to this work Correspondence to: Ma, e-mail:...

10.18632/oncotarget.6737 article EN Oncotarget 2015-12-23

This paper presents an overview of intelligence platform we have built to address threat hunting and incident investigation use-cases in the cyber security domain. Specifically, focus on User Entity Behavior Analytics (UEBA) modules that track monitor behaviors users, IP addresses devices enterprise. Anomalous behavior is automatically detected using machine learning algorithms based Singular Values Decomposition (SVD). Such anomalous indicative potentially malicious activity alerted...

10.1109/bigdata.2016.7840805 article EN 2021 IEEE International Conference on Big Data (Big Data) 2016-12-01

The effective antitumor drug evodiamine (EVO) is attracting increased attention. Therefore, the present study aimed to investigate effects of EVO on proliferation, apoptosis and autophagy human pancreatic cancer (PC) cell lines in vitro vivo. Human PANC‑1 SW1990 PC were treated with different concentrations proliferation was detected using a Cell Counting Kit (CCK)‑8 assay. Colony formation wound‑healing assays showed that inhibited viability migration, flow cytometry. Western blotting...

10.3892/ijo.2020.4956 article EN cc-by-nc-nd International Journal of Oncology 2020-01-10

Abstract Objective Our aim was to evaluate the efficacy and safety of intracoronary autologous bone marrow mesenchymal stem cell (BM-MSC) transplantation in patients with ST-segment elevation myocardial infarction (STEMI). Methods In this randomized, single-blind, controlled trial, STEMI (aged 39–76 years) were enrolled at 6 centers Beijing (The People’s Liberation Army Navy General Hospital, Armed Police Chinese Huaxin Tongren Chaoyang Hospital West Hospital). All underwent optimum medical...

10.1186/s13287-020-02096-6 article EN cc-by Stem Cell Research & Therapy 2021-01-07

Lipid metabolism disorders are associated with degeneration of multiple tissues and organs, but the mechanism crosstalk between lipid disorder intervertebral disc (IDD) has not been fully elucidated. In this study we aim to investigate regulatory abnormal signal on endplate chondrocyte (EPC) senescence calcification.

10.1186/s10020-024-00887-8 article EN cc-by Molecular Medicine 2024-08-09

Abstract Apoptosis plays a pivotal role in pathogen elimination and maintaining homeostasis. However, viruses have evolved strategies to evade apoptosis, enabling their persistence within the host. Z-DNA binding protein 1 (ZBP1) is potent innate immune sensor that detects cytoplasmic nucleic acids activates response clear pathogens. When apoptosis inhibited by viral invasion, ZBP1 can be activated compensate for effect of triggering an response. This review examined mechanisms inhibition...

10.1186/s12964-024-01531-y article EN cc-by Cell Communication and Signaling 2024-02-24

Abstract Background Osteopenia (ON) and osteoporosis (OP) are highly prevalent among postmenopausal women poses a challenge for early diagnosis. Therefore, identifying reliable biomarkers prediction using metabolomics is critically important. Methods Initially, non-targeted was employed to identify differential metabolites in plasma samples from cohort 1, which included healthy controls (HC, n = 23), osteonecrosis (ON, 36), (OP, 37). Subsequently, we performed targeted metabolomic validation...

10.1007/s40520-024-02923-3 article EN cc-by Aging Clinical and Experimental Research 2025-01-21

This paper proposes a method to detect two primary means of using the Domain Name System (DNS) for malicious purposes. We develop machine learning models information exfiltration from compromised machines and establishment command & control (C&C) servers via tunneling. validate our approach by experiments where we successfully malware used in several recent Advanced Persistent Threat (APT) attacks [1]. The novelty is its robustness, simplicity, scalability, ease deployment production environment.

10.1109/icmla.2017.00-71 article EN 2021 20th IEEE International Conference on Machine Learning and Applications (ICMLA) 2017-12-01

Esketamine was approved for the treatment of treatment-resistant depression in 2019. After approval esketamine, numerous concerns have been raised regarding its long-term safety and tolerability. A previous systematic pharmacovigilance study on esketamine-related adverse events (AEs) published 2020; however, it has not updated 2 years later. The primary aim this to detect characterize neurological signals esketamine partially update knowledge field using FDA database. Reporting odds ratio...

10.3389/fphar.2022.849758 article EN cc-by Frontiers in Pharmacology 2022-04-08

Gallbladder cancer (GBC) is the most common and aggressive type of biliary tract cancer. The study potential treatments for GBC has recently focused on microRNAs, a class small non‑coding RNAs, which post‑transcriptionally regulate gene expression during various crucial cell processes. present aimed to investigate role microRNA‑146b (miR‑146b) in GBC. Human tissue adjacent normal gallbladder sections were surgically removed miR‑146b‑5p development pathological characteristics investigated....

10.3892/mmr.2015.3461 article EN Molecular Medicine Reports 2012-03-10

Background Overactive bladder, a syndrome marked by an urgent need to urinate, is globally prevalent ailment. Human health and quality of life are seriously affected. Therefore, it essential investigate the current progress trends in this field. Objective No bibliometric analysis overactive bladder has been conducted. Through use bibliometrics visualization, study intends examine development trend Methods Global publications on between January 2004 August 2022 were extracted from Web Science...

10.3389/fsurg.2022.1078052 article EN cc-by Frontiers in Surgery 2023-01-06

Introduction: CRISPR/Cas9 is a gene-editing technology which could specifically cleave dsDNA and induce target gene mutation. has been widely used in functional studies many fields, such as medicine, biology, agriculture due to its simple design, low cost, high efficiency. Although it well developed model fish freshwater for function analysis, still novel the dealing with economic crustacean species. Methods: In this study, we established system based on microinjection M. nipponense, an...

10.3389/fphys.2023.1141359 article EN cc-by Frontiers in Physiology 2023-03-24

TP53, functioning as the keeper of genome, assumes a pivotal function in inhibition tumorigenesis. Recent studies have revealed that p53 regulates ferroptosis pathways within tumor cells and is closely related to Therefore, we summarize mechanisms by which identify series upstream downstream molecules involved this process. Furthermore, construct p53-ferroptosis network centered on p53. Finally, present progress drugs prevent wild-type (wtp53) degeneration restore wtp53, highlighting...

10.3724/abbs.2023270 article EN cc-by-nc-nd Acta Biochimica et Biophysica Sinica 2023-11-20

Begonia × benariensis series varieties have high ornamental and economic value are excellent for large-area group planting in gardens green areas. At present, the B. grown China rely on foreign imports, price of imported germplasm resources is expensive, which greatly increases cost flower enterprises. In view this, (2n = 2x 34) was used as material, callus treated with colchicine to induce polyploid plants, plants were subjected morphology, DNA content identification, stomatal well...

10.3390/horticulturae10010047 article EN cc-by Horticulturae 2024-01-02
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