A5050254908- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Musculoskeletal synovial abnormalities and treatments
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Cancer-related molecular mechanisms research
- AI in cancer detection
- COVID-19 diagnosis using AI
- Neural Networks and Applications
- Cardiac Imaging and Diagnostics
- Neural Networks and Reservoir Computing
- Sleep and Work-Related Fatigue
- Adipose Tissue and Metabolism
- Head and Neck Cancer Studies
- Stock Market Forecasting Methods
- Image Retrieval and Classification Techniques
- Machine Learning in Bioinformatics
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Color perception and design
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Bone and Joint Diseases
- Endometrial and Cervical Cancer Treatments
Sun Yat-sen Memorial Hospital
2015-2025
Sun Yat-sen University
2015-2025
Guangzhou University of Chinese Medicine
2019-2024
Dongguan University of Technology
2022-2023
Northeast Petroleum University
2020
Tsinghua University
2004-2013
Xi'an Honghui Hospital
2011
The First Affiliated Hospital, Sun Yat-sen University
2010
Nanyang Technological University
2002
Objective Impaired hepatic fatty acids oxidation results in lipid accumulation and redox imbalance, promoting the development of liver diseases insulin resistance. However, underlying pathogenic mechanism is poorly understood. Krüppel-like factor 16 (KLF16) a transcription that abounds liver. We explored whether by what mechanisms KLF16 affects catabolism to improve hepatosteatosis Design expression was determined patients with non-alcoholic disease (NAFLD) mice models. The role regulation...
Rationale: Peripheral nerve injury (PNI) is a great challenge for regenerative medicine. Nerve autograft the gold standard clinical PNI repair. Due to its significant drawbacks, artificial guidance conduits (NGCs) have drawn much attention as replacement therapies. We developed combinatorial NGC consisting of longitudinally aligned electrospun nanofibers and porcine decellularized matrix hydrogel (pDNM gel). The in vivo capacity facilitating tissue regeneration functional recovery was...
Breast cancer HER2 expression has been redefined using a three-tiered system, with HER2-zero cancers considered ineligible for HER2-targeted therapy, HER2-low candidates novel drugs, and HER2-positive treated traditional medications.
To determine the predictive value of pretreatment MRI texture analysis for progression-free survival (PFS) in patients with primary nasopharyngeal carcinoma (NPC). Ethical approval by institutional review board was obtained this retrospective analysis. In 79 NPC, tumour performed on T2 and contrast-enhanced T1-weighted images (T2WIs CE-T1WIs). The Cox proportional hazards model used to association features, volume tumour-node-metastasis (TNM) stage PFS. Survival curves were plotted using...
Currently dual-energy X-ray absorptiometry (DXA) and phantom-based quantitative computed tomography (PB-QCT) have been utilized to diagnose osteoporosis widely in clinical practice. While traditional phantom-less QCT (PL-QCT) is limited by the precision of manual calibration using body tissues, such as fat muscle.The aim this study validate accuracy one newly-developed automatic PL-QCT system measure spinal bone mineral density (BMD) osteoporosis.A total 36 patients were enrolled for...
Purpose To evaluate the diagnostic performance of quantitative parameters derived from dual-energy CT for preoperative diagnosis metastatic sentinel lymph nodes (SLNs) in participants with breast cancer. Materials and Methods For this prospective study, dual-phase contrast agent–enhanced was performed female cancer June 2015 to December 2017. Quantitative morphologic were compared between nonmetastatic SLNs. The fitted univariable multivariable logistic regression models. role analyzed by...
Preoperative Diagnosis of Regional Lymph Node Metastasis Colorectal Cancer With Quantitative Parameters From Dual-Energy CTZehong Yang1,2, Xiang Zhang1,2, Mengjie Fang3,4, Guolin Li2,5, Xiaohui Duan1,2, Jiaji Mao1,2 and Jun Shen1,2Audio Available | Share
Shear-wave elastography (SWE) can improve the diagnostic specificity of B-model ultrasonography (US) in breast cancer. However, whether deep learning-based radiomics signatures based on B-mode US (B-US-RS) or SWE (SWE-RS) could further performance remains to be investigated. We aimed develop B-US-RS and SWE-RS determine their performances classifying masses.This retrospective study included 291 women (mean age ± standard deviation, 40.9 12.3 years) from two centers who had US-visible solid...
Ginsenoside Rg2 has been previously reported to reduce glucose production and adipogenesis in adipose tissue. However, the effects of ginsenosides on hepatic lipid metabolism remain vacant. In this study, we found that ginsenoside treatment significantly attenuated oleic acid palmitic (OA&PA)-induced intracellular deposition oxidative stress mouse primary hepatocytes. C57BL/6J mice are fed with a high-fat diet (HFD) treated displayed decreased body weight, reversed steatosis, improved...
Microemulsion flooding is a effective enhanced oil recovery for low permeability. In this paper, combined the advantage of sulphobetaine surfactant and gemini surfactant, kind (DPSB) was used to prepared microemulsion. The oil–water interfacial tension adsorption different concentration measured evaluate DPSB property. stability microemulsion, microemulsion volume percentage, solubilisation parameter relative phase volume, viscosity also measured. performance further optimized by adding...
CT is increasingly detecting thyroid nodules. Prior studies indicated a potential role of CT-based radiomics models in characterizing nodules, although these lacked external validation.
Acetaminophen (APAP) toxicity leads to severe acute liver injury (ALI) by inducing excessive oxidative stress, inflammatory response, and hepatocyte apoptosis. Imperatorin (IMP) is a furanocoumarin from Angelica dahurica, which has antioxidant anti-inflammatory effects. However, its potential ameliorate ALI unknown. In this study, APAP-treated genetic knockout of Farnesoid X receptor (FXR) Sirtuin 1 (SIRT1) mice were used for research. The results revealed that IMP could improve the severity...
Objective To establish a combined radiomics-clinical model for the early prediction of prostate-specific antigen(PSA) response in patients with metastatic castration-resistant prostate cancer(mCRPC) after treatment abiraterone acetate(AA). Methods The data total 60 mCRPC from two hospitals were retrospectively analyzed and randomized into training group(n=48) or validation group(n=12). By extracting features biparametric MRI, including T2-weighted imaging(T2WI), diffusion-weighted...