A5016484050- Radiomics and Machine Learning in Medical Imaging
- Sarcoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Bone Tumor Diagnosis and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Cancer Diagnosis and Treatment
- Bone health and treatments
- Management of metastatic bone disease
- Laser Applications in Dentistry and Medicine
- FOXO transcription factor regulation
- Inflammatory mediators and NSAID effects
- Organometallic Compounds Synthesis and Characterization
- Neuroscience and Neural Engineering
- Cancer Genomics and Diagnostics
- Renal and related cancers
- Planarian Biology and Electrostimulation
- Thyroid Cancer Diagnosis and Treatment
- Carcinogens and Genotoxicity Assessment
- Metal and Thin Film Mechanics
- Silicone and Siloxane Chemistry
- Cancer Cells and Metastasis
- Pancreatic and Hepatic Oncology Research
- Cancer-related gene regulation
- Advanced X-ray and CT Imaging
- Angiogenesis and VEGF in Cancer
Beijing Tongren Hospital
2024-2025
Capital Medical University
2024-2025
Ruijin Hospital
2023-2025
Shanghai Jiao Tong University
2023-2025
Shantou Central Hospital
2018-2024
First Affiliated Hospital of Wenzhou Medical University
2021-2023
Wenzhou Medical University
2021-2023
The monitoring of tissue regeneration is particularly important. However, most materials do not allow direct observation the process in cartilage layer. Here, using sulfhydryl polyhedral oligomeric silsesquioxane (POSS-SH) as a nano-construction platform, poly(ethylene glycol) (PEG), Kartogenin (KGN), hydrogenated soya phosphatidylcholine (HSPC), and fluorescein are linked through "click chemistry" method to construct nanomaterial with fluorescence visualization for repair: POSS PEG, KGN,...
CT is increasingly detecting thyroid nodules. Prior studies indicated a potential role of CT-based radiomics models in characterizing nodules, although these lacked external validation.
Electrical stimulation enhances cellular activity, promoting tissue regeneration and repair. However, specific cells maintaining a stable energy supply are challenges for precise cell electrical therapy. Here, force-electric conversion hydrogel microspheres (Piezo@CR MPs) is devloped to induce stem aggregation promote chondrogenic differentiation through localized stimulation. These MPs contain barium titanate (BT) nanoparticles embedded in hyaluronic acid methacrylate MPs, with polydopamine...
To prepare a novel hyaluronic acid methacrylate (HAMA) hydrogel microspheres loaded polyhedral oligomeric silsesquioxane-diclofenac sodium (POSS-DS) patricles, then investigate its physicochemical characteristics and in vitro vivo biological properties.Using sulfhydryl POSS (POSS-SH) as nano-construction platform, polyethylene glycol DS were chemically linked through the "click chemistry" method to construct functional nanoparticle POSS-DS. The composition was analyzed by nuclear magnetic...
<title>Abstract</title> <bold>Background: </bold>Osteosarcoma is the most prevalent primary malignant bone tumor. Radiomic models demonstrate promise in globally evaluating prognosis of osteosarcoma; however, they lack biological interpretability. We aimed to develop a radiomic model using MRI predict disease-free Survival (DFS) osteosarcoma patients, and provide underlying pathobiology model. <bold>Methods:</bold> This retrospective study included 270 patients (training set, n=166; external...
Abstract Purpose: To develop a radiomics-based model from preoperative magnetic resonance imaging (MRI) for predicting the histopathological grades of myxofibrosarcoma. Methods: This retrospective study included 54 patients. The tumors were classified into high-grade and low-grade tumor size, signal intensity heterogeneity, margin, surrounding tissue evaluated on MRI. Using least absolute shrinkage selection operator (LASSO) algorithms, 1037 radiomics features obtained fat-suppressed...