A5027707285- Cancer Cells and Metastasis
- Ferroptosis and cancer prognosis
- Epigenetics and DNA Methylation
- Pancreatic and Hepatic Oncology Research
- Fibroblast Growth Factor Research
- Healthcare and Venom Research
- RNA modifications and cancer
- Herpesvirus Infections and Treatments
- Medicinal Plant Pharmacodynamics Research
- Acne and Rosacea Treatments and Effects
- Colorectal Cancer Treatments and Studies
- Kidney Stones and Urolithiasis Treatments
- Single-cell and spatial transcriptomics
- Frailty in Older Adults
- Immune Cell Function and Interaction
- Hepatocellular Carcinoma Treatment and Prognosis
- Traditional Chinese Medicine Analysis
- Wnt/β-catenin signaling in development and cancer
- Head and Neck Surgical Oncology
- Chromatography in Natural Products
- CAR-T cell therapy research
- Immunotherapy and Immune Responses
- Medical Research and Treatments
- Total Knee Arthroplasty Outcomes
- Chemical synthesis and alkaloids
Chinese PLA General Hospital
2024-2025
ZheJiang Academy of Agricultural Sciences
2025
Ministry of Agriculture and Rural Affairs
2025
Chinese People's Liberation Army
2025
Second Affiliated Hospital of Nanchang University
2022-2024
Nanchang University
2022-2024
Shanghai Clinical Research Center
2024
Zhejiang University
2024
First Affiliated Hospital Zhejiang University
2024
Yangtze University
2023
Background Empirical research has consistently documented the concurrent manifestation of frailty and chronic kidney disease (CKD). However, existence a reverse causal association or influence confounding variables on these correlations remains ambiguous.
Tea polyphenols are a class of natural plant compounds with potent antioxidant properties, and their critical role in regulating lipid metabolism has been demonstrated numerous studies. However, systematic research on the effects tea lion-head geese remains limited. In this study, we examined impact through an integrative analysis transcriptomics metabolomics. A total 240 healthy male similar body weights at 1 day age were randomly allocated into two treatment groups (6 replicates per group,...
We have thoroughly reviewed Zhou et al.'s article titled "Association between Kidney Stones and CKD: A Bidirectional Mendelian Randomization Study," published in JASN wish to extend our sincere appreciation.1 Through the application of two-sample randomization (MR), genetic correlation analysis, observational studies, authors effectively examined causal relationships, comorbid characteristics, underlying biologic mechanisms linking kidney stones CKD.1 Their rigorous insightful methodologies...
Abstract Bladder cancer (BLCA) is the 9th most common of mortality. Autophagy and epithelial to mesenchymal transition (EMT) have an essential role in invasion metastasis. However, relationship between autophagy EMT still poorly understood BLCA. Functional enrichment pathway network analysis were carried out. Comprehensive protein-protein interactions (PPI) networks proposed prioritize candidate autophagy-related genes. Furthermore, signature a nomogram model established by integrating...
Bladder cancer (BLCA) is a malignant tumor associated with unfavorable outcomes. Studies suggest that anoikis plays crucial role in progression and cell metastasis. However, its specific bladder remains poorly understood. Our objective was to identify anoikis-related genes (ARGs) subsequently construct risk model assess their potential for predicting the prognosis of cancer.The transcriptome data clinical BLCA patients were sourced from The Cancer Genome Atlas GEO database. We then performed...
Abstract Background The applicability of robot‐assisted resection for huge hepatocellular carcinoma (HCC) ≥10 cm remains contentious with limited available data. Methods This retrospective analysis involved 337 patients who underwent robotic liver HCC by a single surgeon. Propensity score matching (PSM) was employed to compare perioperative indicators between regular and HCC. Results group exhibited shorter median operative duration than the group. IWATE criteria revealed higher scores in No...
DNA somatic mutations of EGFR, KRAS, BRAF and PIK3CA in the epidermal growth factor receptor (EGFR) signaling pathway play critical roles response or resistance tumors to targeted therapy with tyrosine kinase inhibitors (EGFR-TKIs). To provide a high-throughput (HTP) clinical testing service for detecting these mutations, we developed novel platform, SurPlex®-xTAG70plex-EGFR liquidchip.This platform was based on universal 100-tag system. The procedures multiplex PCR, allele specific primer...
This retrospective study was to investigate the efficacy of Gasserian ganglion pulsed radiofrequency therapy (PRF) combined with low-dose morphine injection in treatment refractory ophthalmic herpetic neuralgia.
Bladder cancer (BC), the predominant urological malignancy in men, exhibits complex molecular underpinnings contributing to its progression. This investigation aims elucidate expression dynamics of calcium-binding protein 39 (CAB39) both healthy and cancerous tissues explore functional role epithelial-mesenchymal transition (EMT) within human bladder contexts. Utilizing immunohistochemistry quantitative reverse transcription analyses, we assessed CAB39 across BC specimens cell lines....
Background: Tumor metastasis and poor drug efficacy are two of the prominent causes therapeutic failure in tumor patients. The underlying molecular mechanism requires further exploration novel effective curative strategies urgently needed. Nature is a rich source for discovery Lycorine hydrochloride (Lyc.HCL) natural alkaloid with tremendous potential. However, mechanisms anti-tumor still elusive. In current study, we investigated effects Lyc.HCL against esophageal squamous cell carcinomas...
To determine the efficacy of betamethasone injection combined with famciclovir on herpes zoster and its effects cytokines. The clinical data 89 patients treated in our hospital between October 2020 June 2023 were analyzed retrospectively. Among them, 42 (0.25 g) included control group, other 47 both (1 ml) study group. levels serum inflammatory factors (interleukin-6 interleukin-10) two groups compared before after treatment. visual analogue scale was adopted for evaluating comparing pain...
It has became a hotspot research about the target metastasis of malignant tumor in recent years. been proven that is nonrandom but highlyorganized and selective process. The aim this study by analysing expression CC Chemokine Receptor 7 (CCR7) pulmonary tissue metastasized lymph nodes NSCLC, to explore relationship between CCR7 nodes, significance.SABC immunohitochemcal staining was used investigate rabbit anti-human monoclonal antibody, specimens were 17 cases adenocarcinoma, Squamous cell...
Objective To investigate the clinical effect of absorbable calcium sulfate in treatment early infection after joint replacement. Methods From August 2015 to January 2018, Orthopedics Department Three, Zhongshan Hospital nine patients with replacement were selected for a retrospective analysis. All cases showed good prosthesis location, without loosening. The symptoms last an average period (10±3)d. adopted thorough debridement, retaining prosthesis. drug-loaded particles inserted into...