A5013463795- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Studies on Chitinases and Chitosanases
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Phytoplasmas and Hemiptera pathogens
- Plant-Microbe Interactions and Immunity
- Actinomycetales infections and treatment
- Infections and bacterial resistance
- Pleural and Pulmonary Diseases
- Clinical Laboratory Practices and Quality Control
- Peptidase Inhibition and Analysis
- Pneumocystis jirovecii pneumonia detection and treatment
- Nematode management and characterization studies
- Medicinal Plants and Neuroprotection
- Fungal Biology and Applications
- Galician and Iberian cultural studies
- Cystic Fibrosis Research Advances
- Technology in Education and Healthcare
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
Hospital Posadas
2011-2025
Critically ill COVID-19 patients are at high risk for invasive fungal infections (IFIs). Data on IFI prevalence in severe Latin America is scarce. This study aimed analyzing the and outcomes of IFIs from Argentina. For this purpose, a retrospective was conducted admitted to intensive care unit hospital Buenos Aires between 2020 2022, with mycological evidence IFI. A total 86 cases were reported, including 50 COVID-19-associated candidiasis (CAC), 29 pulmonary aspergillosis (CAPA), 10...
Invasive pulmonary aspergillosis is a complication in critically ill patients with acute respiratory distress syndrome, especially those severe coronavirus disease-associated pneumonia. In this study, five cases of presumed invasive one immunocompromised and four immunocompetent COVID-19 Buenos Aires are described. all cases, the underlying conditions, clinical presentation, fungal diagnostic tests used their results, features chest scan images, antifungals outcomes detailed.
Abstract The National Reference Laboratory in Clinical Mycology of Argentina conducted a retrospective review human coccidioidomycosis cases diagnosed by the Network between 2010 and 2022 to determine burden disease country. A total 100 were documented, with higher prevalence male patients (male-to-female ratio 1.9:1), median age 41 years. Comparing number two 10-year periods (2000–2009 2010–2019), increase was 36.51% (from 63 86 cases). Among recorded cases, 79 tested positive using double...
The patients with severe COVID-19 are at increased risk for invasive fungal infections, such as pulmonary aspergillosis and candidiasis, which increase morbidity mortality. However, clinicians should also consider the possibility of reactivating latent Histoplasma capsulatum in living within areas endemicity who have worsening respiratory function or sepsis, even if they do not classical factors histoplasmosis (e.g., HIV/AIDS). Bearing mind this scenario, serum samples 39 non-HIV/AIDS from...
Information on paracoccidioidomycosis (PCM) in Argentina is fragmented and has historically been based estimates, supported only by a series of few reported cases. Considering the lack global information, national multicentric study order to carry out more comprehensive analysis was warranted. We present data including demographic clinical aspects historical 466 cases recorded over 10 years (2012-2021). Patients were aged from 1 89 years. The general male: female (M:F) ratio 9.5:1 with...
Invasive fungal infections as aspergillosis and candidiasis are well-documented complications in critically ill patients with acute respiratory distress syndrome due to COVID-19. However, invasive by other molds rarely reported. We describe a case of fusariosis patient severe COVID-19 fatal outcome.
Abstract The impact of COVID‐19 on paracoccidioidomycosis (PCM) in Argentina and the consequences generated by pandemic are discussed. From 2018 to 3 years after declaration, 285 proven PCM patients were registered. No association between both diseases was documented. frequency decreased extremely low levels 2020. Mandatory social isolation emotional psychological effects under circumstances led delays diagnosis, severe disseminated cases, other challenges for diagnosis subsequent years....
Summary Background Triazole resistance in Aspergillus fumigatus sensu stricto due to mutations the cyp51A gene has been widely reported. Data from Argentina, and particularly cystic fibrosis (CF) patients, are limited. Objectives To investigate prevalence molecular mechanisms of azole A. recovered this population. Methods Ninety‐three isolates 50 CF patients were retrospectively analysed for using standard microbroth dilution method according CLSI M38‐A2 guidelines. Sequencing analysis its...
Abstract Background Diagnosing progressive disseminated histoplasmosis (PDH) is still challenging in many countries where this disease highly endemic. Definitive diagnosis established by culture and/or cytology/histopathology but both procedures have limited sensitivity and cultures are time‐consuming. Antibodies detection immunodiffusion has a low immunocompromised individuals. Commercially available antigen assays high PDH cases; however, they expensive only performed few laboratories....
La histoplasmosis diseminada es una micosis sistémica endémica, causada por el hongo dimórfico Histoplasma capsulatum. Las manifestaciones clÃnicas dependen de la carga fúngica inhalada, del estado inmunológico paciente y virulencia cepa infectante. variante más frecuente en inmunocomprometidos, registrándose 90% los casos pacientes con serologÃa positiva para VIH. En esta serie se evaluaron 37 diagnóstico infección VIH e diseminada. El 43,2% no sabÃa su forma previa a consulta...
Abstract Definitive diagnosis of histoplasmosis relies on culture and/or cytology/histopathology; however, these procedures have limited sensitivity and cultures are time-consuming. Antibodies detection by immunodiffusion has low in immunocompromised individuals uses histoplasmin (HMN), a crude antigenic extract, as reagent. Novel protein antigen candidates been recently identified produced DNA-recombinant techniques to obtain standardized specific reagents for diagnosing histoplasmosis. To...
Abstract Patients with severe COVID-19 are at increased risk for invasive fungal infections, which underestimated. Histoplasmosis reactivation in endemic areas should not be overlooked this population. In a previous study, seroconversion to anti-histoplasmin antibodies by ELISA was detected 6/39 (15.4%) patients COVID-19. work, samples were further investigated detect against the Histoplasma capsulatum 100-kDa antigen (Hcp100) ELISA. Seroconversion anti-Hcp100 7/39 patients, of whom 6 also...
In cystic fibrosis (CF) patients, fungal colonization of the respiratory tract is frequently found. Aspergillus fumigatus, Scedosporium genus, and Exophiala dermatitidis are most commonly isolated moulds from secretions CF patients. The aim this 5-year surveillance study was to identify trends in species distribution susceptibility patterns 212 mould strains identified as spp., sputum 63 patients who received long-term therapy with itraconazole (ITR) and/or voriconazole (VRC). isolates were...