Xiaoping Chen

ORCID: 0000-0002-9359-7023
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About
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Research Areas
  • GDF15 and Related Biomarkers
  • Blood Pressure and Hypertension Studies
  • Cardiac Fibrosis and Remodeling
  • Nuclear Receptors and Signaling
  • Hormonal Regulation and Hypertension
  • Cardiovascular Health and Disease Prevention
  • Sodium Intake and Health
  • Macrophage Migration Inhibitory Factor
  • Folate and B Vitamins Research
  • IgG4-Related and Inflammatory Diseases
  • Cardiovascular Function and Risk Factors
  • Pancreatitis Pathology and Treatment
  • Diabetic Foot Ulcer Assessment and Management
  • Urticaria and Related Conditions
  • Mycobacterium research and diagnosis
  • Neuroendocrine Tumor Research Advances
  • Renal and Vascular Pathologies
  • Congenital Diaphragmatic Hernia Studies
  • Bipolar Disorder and Treatment
  • Electrospun Nanofibers in Biomedical Applications
  • Birth, Development, and Health
  • Amoebic Infections and Treatments
  • Cancer, Lipids, and Metabolism
  • Congenital heart defects research
  • Mast cells and histamine

Taiyuan Central Hospital
2014-2025

Sichuan University
2014-2024

West China Hospital of Sichuan University
2018-2024

Angiogenesis has been considered a pivotal strategy for treating ischemic heart disease. One possible approach, the Shexiang Baoxin Pill (MUSKARDIA), noted to promote angiogenesis, but its underlying mechanism is still largely unknown. We aimed determine effects of MUSKARDIA on acute myocardial infarction (AMI), as well mechanistic bases. AMI was induced in rats, using left anterior descending coronary arterial occlusion, and either 6 (low) or 12 (high-dose) mg/kg/day administered 56 days....

10.1016/j.biopha.2023.115186 article EN Biomedicine & Pharmacotherapy 2023-07-21

Basic fibroblast growth factor (bFGF) and platelet-derived (PDGF) have been shown to be involved in a spectrum of cellular processes. In previous study, we constructed novel multigenic vector that contained two separate transcription units, each consisting strong promoter an efficient polyadenylation signal. The promoters were chosen for their ability work simultaneously. Dual gene transfer bFGF PDGF single plasmid resulted significant increase collateral blood vessel formation rabbit model...

10.3892/etm.2014.1485 article EN Experimental and Therapeutic Medicine 2014-01-14

To explore the correlation between growth differentiation factor 15 (GDF-15) -3148C/G polymorphism and formation of collateral circulation in acute ST-elevation myocardial infarction (STEMI) Han population Taiyuan area.The present study included 92 STEMI patients 56 normal controls based on coronary angiography; group was divided into non-collateral according to Rentrop's grading method. Polymerase chain reaction (PCR) DNA sequencing methods were used detect analyze GDF-15 all...

10.1590/1806-9282.63.12.1049 article EN Revista da Associação Médica Brasileira 2017-12-01

Abstract Research reports on associations of urinary sodium excretion with central hemodynamic parameters and vascular changes are quite limited in general or non‐hypertensive population. The purpose the current study was to explore such Chinese Tibetans living at high altitude. This cross‐sectional conducted Luhuo County, Ganzi Tibetan Autonomous Prefecture average elevation 3800 meters from December 2018 January 2019. A total 294 were included study. Twenty‐four hour estimated by second...

10.1111/jch.14356 article EN Journal of Clinical Hypertension 2021-09-03

Background Ventricular septal rupture (VSR) is a serious complication occurring after myocardial infarction (MI). Cardiogenic shock (CS) common of VSR and an important factor affecting its prognosis. CS can occur in either immediate or delayed manner VSR; however, studies on the risk factors associated with are scarce. Methods We retrospectively studied patients diagnosed MI admitted to West China Hospital between September 2009 August 2023. Demographic data, medical history, physical...

10.3389/fcvm.2023.1230169 article EN cc-by Frontiers in Cardiovascular Medicine 2023-11-23

Abstract Background There is limited evidence regarding the relationship between lipid parameters and vascular mechanical characteristics in normotensive population without diabetes mellitus. The aim of this study was to identify an association changes men women, women before after menopause. Methods Six hundred-seventy patients who underwent functional testing fulfilled inclusion exclusion criteria were enrolled our cross-sectional study. All participants from Qinghai–Tibet Plateau (Luhuo...

10.1186/s12872-022-02801-8 article EN cc-by BMC Cardiovascular Disorders 2022-08-05

10.1016/j.jacc.2015.06.594 article EN publisher-specific-oa Journal of the American College of Cardiology 2015-10-01

10.1016/j.jacc.2015.06.387 article EN publisher-specific-oa Journal of the American College of Cardiology 2015-10-01

Objective To summarize the clinical features of autoimmune pancreatitis (AIP) with diabetes as initial symptom. Methods The data one case AIP symptom were analyzed. The 60-year-old male patient was diagnosed in March 2015 Department Endocrinology China-Japan Friendship Hospital. A follow-up study focused on pancreatic endocrine and exocrine functions conducted. Results Based observation, insulin secretion function poor, whereas glutamic acid decarboxylase antibody, autoantibody...

10.3760/cma.j.issn.1674-5809.2016.07.008 article EN Chin J Diabetes Mellitus 2016-07-27
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