A5024726592- Transplantation: Methods and Outcomes
- Renal Transplantation Outcomes and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Organ Transplantation Techniques and Outcomes
- Polyomavirus and related diseases
- Hematopoietic Stem Cell Transplantation
- Medical Imaging and Pathology Studies
- Cancer Genomics and Diagnostics
- Tracheal and airway disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Bone and Joint Diseases
- Pulmonary Hypertension Research and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Viral Infections and Immunology Research
- Anesthesia and Neurotoxicity Research
- Ultrasound in Clinical Applications
- Organ and Tissue Transplantation Research
- Hematological disorders and diagnostics
- Complement system in diseases
- Acute Myeloid Leukemia Research
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Vascular Anomalies and Treatments
University of Maryland, Baltimore
2021-2025
University of Maryland Medical Center
2021-2025
National Heart Lung and Blood Institute
2020-2022
Digital Research Alliance of Canada
2022
National Institutes of Health
2021-2022
MedStar Georgetown University Hospital
2016
Georgetown University
2016
INTRODUCTION. The clinical course of coronavirus 2019 (COVID-19) is heterogeneous, ranging from mild to severe multiorgan failure and death. In this study, we analyzed cell-free DNA (cfDNA) as a biomarker injury define the sources tissue that contribute such different trajectories.
Rationale: The association of acute cellular rejection (ACR) with chronic lung allograft dysfunction (CLAD) in transplant recipients has primarily been described before consensus recommendations incorporating restrictive phenotypes. Furthermore, the degree molecular injury during ACR CLAD or death remains undefined. Objectives: To investigate risk and to further if this depends on injury. Methods: This multicenter, prospective cohort study included 188 recipients. Subjects underwent serial...
Abstract Background Hyperammonemia syndrome (HS) is a life-threatening complication primarily affecting lung transplant recipients (LTR) and associated with M. hominis and/or Ureaplasma spp infection. We implemented an active surveillance prophylaxis protocol to improve outcomes HS in LTR. Herein, we evaluate the impact of our on HS. Methods This single-center retrospective cohort study adult LTR performed from 1/1/2019 1/31/2024. Our was 8/1/2022 included PCR testing for post-operative...
Background. A prior single-center, retrospective cohort study identified baseline lung allograft dysfunction (BLAD) as a risk factor for death in bilateral transplant recipients. In this multicenter prospective study, we test the association of BLAD with recipients, identify clinical factors BLAD, and assess its injury on molecular level. Methods. This multicenter, included 173 recipients that underwent serial pulmonary function testing plasma collection donor-derived cell-free DNA at...
Pulmonary chronic graft-versus-host disease (PcGVHD) is a devastating complication of allogeneic hematopoietic stem cell transplant (HCT). The 2014 National Institutes Health cGVHD consensus criteria (NIH criteria) only captures bronchiolitis obliterans syndrome (BOS). In this study, we adapted the 2019 International Society for Heart and Lung Transplantation (ISHLT) lung allograft dysfunction (CLAD) to define novel phenotypes PcGVHD compared performance with NIH identify patients high-risk...