Pirunthan Pathmarajah

ORCID: 0000-0002-9395-5935
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About
Contact & Profiles
Research Areas
  • Dermatology and Skin Diseases
  • Skin and Cellular Biology Research
  • Cell Adhesion Molecules Research
  • Cutaneous Melanoma Detection and Management
  • Reconstructive Facial Surgery Techniques
  • Contact Dermatitis and Allergies
  • Ear and Head Tumors
  • Skin Protection and Aging
  • Urticaria and Related Conditions
  • Medicine and Dermatology Studies History
  • Medical Malpractice and Liability Issues
  • Vasculitis and related conditions
  • Mast cells and histamine
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Dermatological and Skeletal Disorders
  • Psoriasis: Treatment and Pathogenesis
  • Microscopic Colitis
  • Social Media in Health Education
  • Silk-based biomaterials and applications
  • Nonmelanoma Skin Cancer Studies
  • RNA regulation and disease
  • Nail Diseases and Treatments
  • Head and Neck Anomalies
  • Body Image and Dysmorphia Studies
  • Empathy and Medical Education

Stanford University
2024-2025

Barts Health NHS Trust
2021-2024

Royal London Hospital
2024

Guy's and St Thomas' NHS Foundation Trust
2024

St. John's School
2023

Broomfield Hospital
2022

Sandwell & West Birmingham Hospitals NHS Trust
2020-2021

Whipps Cross University Hospital
2017

London Clinic
2017

University College London
2015

Abstract Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic disorder due to pathogenic variants in the COL7A1 gene. In this study we determined association between different categories of and clinical disease severity 236 RDEB patients North America. Published reports or in-silico predictions were used assess impact on type VII collagen (C7) protein function. Three postulated: genotypes that would likely cause low C7 function (splice B/missense, missense/missense), medium...

10.1093/bjd/ljaf015 article EN British Journal of Dermatology 2025-01-10

Letrozole, an aromatase inhibitor, is a commonly used neo-adjuvant drug to treat hormone-sensitive breast cancer. There have been few cases of inhibitor induced vasculitis but the first case letrozole-induced was reported from Switzerland in 2014 (Digklia et al.) [1].We report 72-year-old woman with small She started on pre-operative letrozole (2.5mg/d) whilst awaiting surgery. Ten days later she presented burning pain and purpuric skin lesions which progressed extensive ischaemic...

10.1016/j.ijscr.2015.09.024 article EN International Journal of Surgery Case Reports 2015-01-01

The COVID-19 pandemic has necessitated intensified handwashing and mask usage for healthcare staff. A retrospective cross-sectional study was performed primarily to investigate the potential skin damage secondary impacts on wellbeing of staff resulting from these practices. Additionally availability uptake occupational health services moisturisers in work place also assessed. survey distributed NHS between April May 2020 asked questions regarding damage, impact utilisation input...

10.1111/dth.14885 article EN Dermatologic Therapy 2021-02-17

Hidradenitis suppurativa (HS) is a chronic relapsing, remitting disease which results in the formation of inflammatory nodules and pustules intertriginous areas. HS complex with known psychosocial impact. Adalimumab biologic, used for treatment resistant HS, working by inactivating TNF-alpha. Our primary objective was to determine effects adalimumab on HS-PGA DLQI scores patients that had been at least 6 months. secondary note assess significance adverse impacts wider health, namely...

10.1111/dth.14643 article EN Dermatologic Therapy 2020-12-10

Diagonal ear lobe creases, often known as Frank's sign, are a folding in the skin of lobe. Many studies have found an association between diagonal creases and coronary artery disease. To our knowledge, this is first report paired helix. They may similar relevance to cardiovascular disease creases. We case 68-year-old South Asian man with crease. On closer inspection auricle, he also had on helix same side. postulate that formed due pressure during sleep hard surface. The pathophysiological...

10.7759/cureus.1884 article EN Cureus 2017-11-27

The role of pharmacists in psychodermatology includes counseling patients on psychotropic medications, ensuring adherence, and providing guidance that complements the advice dermatology health care professionals. This pilot study is first to highlight discrepancies counselling effectiveness between clinicians pharmacists. Patients were provided with suboptimal, conflicting or contradictory training specialized prescribing privileges specific information medications are essential.

10.1093/bjd/ljae411 article EN British Journal of Dermatology 2024-10-25

Abstract Chronic actinic dermatitis (CAD) is characterized by a photoexposed site in association with objective evidence of photosensitivity, often arising on background atopic (AD). Dupilumab monoclonal antibody that inhibits signalling interleukin (IL)-4 and IL-13 licensed for the management moderate-to-severe AD. To date, nine case reports have suggested dupilumab can be clinically effective CAD, yet only five cases had diagnostic baseline phototesting two could demonstrate improvement...

10.1093/bjd/ljad113.344 article EN British Journal of Dermatology 2023-06-01

This article has been withdrawn at the request of author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. full Elsevier Policy on Article Withdrawal can be found https://www.elsevier.com/about/our-business/policies/article-withdrawal.

10.1016/j.jicc.2017.12.005 article EN Journal of Indian College of Cardiology 2017-12-01
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