A5043169134- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Neonatal and Maternal Infections
- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Infection Control in Healthcare
- Streptococcal Infections and Treatments
- Nosocomial Infections in ICU
- Surgical site infection prevention
- Healthcare cost, quality, practices
- Viral gastroenteritis research and epidemiology
- Skin Protection and Aging
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Dermatology and Skin Diseases
- Microscopic Colitis
- Pediatric health and respiratory diseases
- Allergic Rhinitis and Sensitization
- Urinary Tract Infections Management
- Healthcare Policy and Management
- Medical Device Sterilization and Disinfection
- Asthma and respiratory diseases
- Neuroendocrine regulation and behavior
- Bacterial Infections and Vaccines
Guy's Hospital
2024
John Hunter Hospital
2015-2024
Hunter New England Local Health District
2007-2024
Guy's and St Thomas' NHS Foundation Trust
2020-2024
St John's Hospital
2024
University of Newcastle Australia
2011-2023
Rocky Mountain Research (United States)
2021
New South Wales Department of Health
2017-2020
Hunter Genetics
1997-2018
University of Minnesota
2007-2018
We report an outbreak of Enterobacter sakazakii infection and colonization in neonates related to infant formula contaminated during the manufacturing process. The occurred a 20-bed neonatal intensive care unit six-week period 1988, involved total four infants. Three infants had sepsis three bloody diarrhea; all patients responded intravenous antibiotics recovered without complications. E isolated from same plasmid multilocus enzyme profile as those patients. This demonstrates significance...
BackgroundThe emergence of antimicrobial resistance is particular concern with respect to urinary tract infections, since the majority causative agents are Gram-negative bacteria. Healthcare-associated infections (HAUTIs) frequently associated instrumentation tract, specifically indwelling catheters.AimTo evaluate current incidence, mortality, and length hospital stay HAUTIs.MethodsA non-concurrent cohort study design was used, conducted between January 1st, 2010 June 30th, 2014. All...
The incidence of Clostridium difficile infection (CDI) continues to rise, whilst treatment remains problematic due recurrent, refractory and potentially severe nature disease. C. is a challenge for community hospital-based clinicians. With the advent an expanding therapeutic arsenal against since last published Australasian guidelines, update on CDI recommendations clinicians was required. On behalf Society Infectious Diseases, we present updated guidelines management in adults children.
Neutrophils are the most abundant inflammatory cells at earliest stages of wound healing and play important roles in repair fibrosis. Formyl peptide receptor 1 (FPR-1) is abundantly expressed on neutrophils has been shown to regulate their function, yet importance FPR-1 fibrosis remains ill defined. FPR-1–deficient (fpr1–/–) mice were protected from bleomycin-induced pulmonary but developed renal hepatic normally. Mechanistically, we observed a failure effectively recruit lungs fpr1–/– mice,...
Objectives: CNS infections due to multiresistant Acinetobacter baumannii (MRAB) are an emerging problem in neurosurgical patients. Colistin remains one of the few remaining treatment options for MRAB but has poor penetration. We describe our experience with intraventricular or intrathecal colistin this infection. Methods: Cases known have received were retrospectively reviewed regarding treatment, efficacy and adverse events. Results: Five patients identified. All admissions ICU all cured...
Clostridium difficile is the most common cause of health care-associated and antibiotic-associated diarrhoea. These guidelines are intended to provide advice clinicians on clinical assessment, diagnosis management C. infection (CDI). Hypervirulent strains difficile, including PCR ribotype 027 recently identified in Australia, have been associated elsewhere with epidemic spread high rates severe disease death. Diagnostic tests include stool culture, polymerase chain reaction-based assays,...
Abstract We report an outbreak of Enterobacter sakazakii infection and colonization in neonates related to infant formula contaminated during the manufacturing process. The occurred a 2O-bed neonatal intensive care unit six-week period 1988, involved total four infants. Three infants had sepsis three bloody diarrhea; all patients responded intravenous antibiotics recovered without complications. E isolated from same plasmid multilocus enzyme profile as those patients. This demonstrates...
Human Rhinovirus (HRV) is associated with acute exacerbations of chronic respiratory disease. In healthy individuals, innate viral recognition pathways trigger release molecules direct anti-viral activities and pro-inflammatory mediators which recruit immune cells to support clearance. Interleukin-1alpha (IL-1α), interleukin-1beta (IL-1β) interleukin-18 (IL-18) have critical roles in the establishment neutrophilic inflammation, commonly seen airways infection thought be detrimental We...
Enterococcus faecium is a major nosocomial pathogen causing significant morbidity and mortality worldwide. Assessment of E. using MLST to understand the spread this organism an important component hospital infection control measures. Recent studies, however, suggest that might be inadequate for surveillance. To use WGS characterize recently identified vancomycin-resistant (VREfm) isolates non-typeable by appear multi-jurisdictional outbreak in Australia. Illumina NextSeq Pacific Biosciences...
The venous blood from four species of freshwater fish, rainbow trout (Salmo gairdnerii Richardson), carp (Cyprinus carpio Linnaeus), bullhead (Ameiurus nebulosus Le Sueur) and sucker (Catostomus commersonnii Lacepède) was analyzed an estimate made the probable range physiological CO2 tension.A detailed study transport in two these species, carp, which differ greatly effect on combination oxygen blood. They too, their systems transport. A curious feature is great change packed cell volume...