A5069110941- Ethics in Clinical Research
- Viral Infections and Outbreaks Research
- Ethics in medical practice
- Disaster Response and Management
- Global Security and Public Health
- CRISPR and Genetic Engineering
- Public Health Policies and Education
- Innovation and Socioeconomic Development
- COVID-19 diagnosis using AI
- Vaccine Coverage and Hesitancy
- Biomedical Ethics and Regulation
- Ethics and Legal Issues in Pediatric Healthcare
- Artificial Intelligence in Healthcare and Education
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS Impact and Responses
- Obesity, Physical Activity, Diet
- Food Security and Health in Diverse Populations
- Healthcare cost, quality, practices
- Child and Adolescent Health
- Mosquito-borne diseases and control
- Health and Medical Studies
- Obesity and Health Practices
- COVID-19 Clinical Research Studies
- Science, Research, and Medicine
Baylor College of Medicine
2024
The Geneva Association
2023
INCLEN Trust International
2020-2021
University of Geneva
2020-2021
Indian Institute of Technology Hyderabad
2021
Bioethics International
2021
Ayurvet Research Foundation
2020
National Institute of Technology Delhi
2019
World Health Organization
2011-2019
Barrett Technology (United States)
2018
High social value is fundamental to justifying these studies
Ensuring that countries have adequate research capacities is essential for an effective and efficient response to infectious disease outbreaks. The need ethical principles values embodied in international ethics guidelines be upheld during public health emergencies widely recognized. Public officials, researchers other concerned stakeholders also carefully balance time resources allocated immediate treatment control activities, with approach integrates as part of the outbreak response. Under...
For 30 years, women have sought equal opportunity to be included in trials so that drugs are equitably studied as well men; regulatory guidelines changed accordingly. Pregnant women, however, continue excluded from for non-obstetric conditions, though they been of life-threatening diseases because prospects maternal survival outweighed potential fetal risks. Ebola virus disease is a infection without approved treatments or vaccines. Previous (EBOV) outbreak data showed 89–93% and 100%...
Between 2013 and 2016, West Africa experienced the largest ever outbreak of Ebola Virus Disease. In absence registered treatments or vaccines to control this lethal disease, World Health Organization coordinated supported research expedite identification interventions that could improve future efforts. Consequently, Research Ethics Review Committee (WHO-ERC) was heavily involved in reviews ethics discussions. It reviewed 24 new 22 amended protocols for studies including interventional (drug,...
Implementation research (IR) is growing in recognition as an important generator of practical knowledge that can be translated into health policy. With its aim to answer questions about how improve access interventions have been shown work but not reached many the people who could benefit from them, IR involves a range particular ethical considerations yet comprehensively covered international guidelines on ethics. The fundamental principles governing clinical apply equally IR, application...
Vaccines are among the most cost-effective interventions against infectious diseases. Many candidate vaccines targeting neglected diseases in low- and middle-income countries now progressing to large-scale clinical testing. However, controversy surrounds appropriate design of vaccine trials and, particular, use unvaccinated controls (with or without placebo) when an efficacious already exists. This paper specifies four situations which placebo may be acceptable, provided that study question...
On June 23, 2017, WHO issued the first international ethics guidelines on public health surveillance (appendix),1World Health OrganizationWHO ethical issues in surveillance.http://apps.who.int/iris/bitstream/10665/255721/1/9789241512657-eng.pdfDate: 2017Google Scholar helping to fill a key gap knowledge regarding this important practice. Surveillance constitutes foundation of outbreak and epidemic responses, but it is not only for infectious disease also understanding global challenge...
To assess the current state of national ethics committees and challenges they face.We surveyed between 30 January 21 February 2018.In total, representatives 87 146 (59.6%) participated. The 84 countries covered were in all World Bank income categories Health Organization regions. Many lack resources face several domains, like independence, funding or efficacy. Only 40.2% (35/87) expressed no concerns about independence. Almost a quarter (21/87) did not make any recommendations to their...
In 2016, following pandemic influenza threats and the 2014–2016 Ebola virus disease outbreaks, WHO developed a guidance document for managing ethical issues in infectious outbreaks. this article, we analyse some that have had predominant role decision making response to current COVID-19 but were absent or not addressed same ways 2016 document. A results health crisis social political crises both nationally globally. The implications of these global effects should be properly identified so...
<ns3:p>Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many literature sources and guidance point to the inadequacy individual informed consent any genetically mosquito release, including gene ones, (outside epidemiological studies that might require blood samples) at need a community-level decision, researchers often find themselves with no specific on how decision should be made, expressed by whom....
Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many literature sources and guidance point to the inadequacy individual informed consent any genetically mosquito release, including gene ones, (outside epidemiological studies that might require blood samples) at need a community-level decision, researchers often find themselves with no specific on how decision should be made, expressed by whom. Target...
Abstract Background Polycystic ovary syndrome (PCOS) is a serious health condition affecting women of reproductive age. High prevalence PCOS and associated metabolic complications needs effective treatment management. This study evaluated the efficacy optimal nutraceutical combinations in improving characteristics using system biology-based mathematical modelling simulation. Methods A shortlisting eight potent nutraceuticals was carried out with literature search. Menstrual cycle model used...
Abstract In controlled human infection studies (CHIs), participants are deliberately exposed to infectious agents in order better understand the mechanism of or disease and test therapies vaccines. While most CHIs have been conducted high‐income countries, recently expanding into low‐ middle‐income countries (LMICs). One potential ethical concern about this expansion is challenge obtaining voluntary informed consent participants, especially those who may not be literate limited education....