A5058100112- Ethics in Clinical Research
- Ethics in medical practice
- Public Relations and Crisis Communication
- Educator Training and Historical Pedagogy
- Ethics and Legal Issues in Pediatric Healthcare
- Biomedical Ethics and Regulation
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health and Patient Involvement
- Healthcare cost, quality, practices
- Palliative Care and End-of-Life Issues
- Patient-Provider Communication in Healthcare
- Global Education and Multiculturalism
- Healthcare Policy and Management
- Child and Adolescent Health
- Educational Theory and Curriculum Studies
- Healthcare Decision-Making and Restraints
- Medical Malpractice and Liability Issues
- Neuroethics, Human Enhancement, Biomedical Innovations
- Media Studies and Communication
- Patient Dignity and Privacy
- Nonprofit Sector and Volunteering
- Primary Care and Health Outcomes
- Childhood Cancer Survivors' Quality of Life
- Health Policy Implementation Science
- Global Educational Policies and Reforms
University of Oxford
2016-2025
Wellcome Centre for Ethics and Humanities
2016-2025
Oxford BioMedica (United Kingdom)
2020-2025
Victoria University of Wellington
2010-2023
National Institute for Health Research
2022
St. Francis College
2021
Apple (Israel)
2021
Karlstad University
2021
Oxford University Press (United Kingdom)
2021
University College London
2021
Journal Article Can Broad Consent be Informed Consent? Get access Mark Sheehan * Oxford BRC Ethics Fellow and James Martin Research Fellow, NIHR Biomedical Centre, the Ethox Centre Institute for Science Ethics, University of *Corresponding author: Sheehan, Department Public Health Primary Care, The Oxford, Old Rd Campus, Badenoch Building, Headington, OX3 7LG, UK. Tel.: +44 (0) 1865 287848; Fax: 287884; Email: mark.sheehan@ethox.ox.ac.uk Search other works by this author on: Academic PubMed...
In recent years, there have been prominent calls for a new social contract that accords more central role to citizens in health research. Typically, this has understood as and patients having greater voice within the standard research enterprise. Beyond this, however, it is important renegotiated specifically addresses oversight of new, path-breaking approach research: participant-led light momentum behind its potential advance knowledge by challenging complementing traditional research,...
As the COVID-19 pandemic impacts on health service delivery, providers are modifying care pathways and staffing models in ways that require professionals to be reallocated work critical settings. Many of roles staff being allocated intensive unit emergency department pose additional risks themselves, new policies for reallocation causing distress uncertainty concerned. In this paper, we analyse a range ethical issues associated with changes allocation processes face COVID-19. line dominant...
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This paper reports the process and outcome of a consensus finding project, which began with meeting at Brocher Foundation in May 2015. The project sought to generate reach on standards practice for Empirical Bioethics research. involved 16 academics from 5 different European Countries, range disciplinary backgrounds.The used modified Delphi approach.Consensus was reached 15 practice, organised into 6 domains research (Aims, Questions, Integration, Conduct Work, Normative Work; Training &...
Thus far, little work in bioethics has specifically focused on global health research priority-setting. Yet features of priority-setting raise ethical considerations and concerns related to justice. For example, such processes are often exclusively disease-driven, meaning they rely heavily burden disease considerations. They, therefore, tend undervalue non-biomedical topics, which have been identified as essential helping reduce disparities. In recognition these the limited scholarship...
Background: To date, no treatment for neuromyelitis optica (NMO) has been granted regulatory approval, and controlled clinical studies have reported. Objective: design a placebo-controlled study in NMO that appropriately balances patient safety clinical–scientific integrity. Methods: We assessed the “standard of care” to establish ethical framework trial. implemented measures balance need scientific robustness while mitigating risks associated with study. The medical or community,...
Abstract Background In many countries, committees make priority-setting decisions in order to control healthcare costs. These take into account relevant criteria, including clinical effectiveness, cost-effectiveness, and need, are supported by evidence usually drawn from economic studies. sources of do not include the specific perspective information that patients can provide about condition treatment. Methods Drawing on arguments political philosophy ethics ethical basis for bodies, authors...
Vaccines are among the most cost-effective interventions against infectious diseases. Many candidate vaccines targeting neglected diseases in low- and middle-income countries now progressing to large-scale clinical testing. However, controversy surrounds appropriate design of vaccine trials and, particular, use unvaccinated controls (with or without placebo) when an efficacious already exists. This paper specifies four situations which placebo may be acceptable, provided that study question...
There is a rich tradition in bioethics of gathering empirical data to inform, supplement, or test the implications normative ethical analysis. To this end, bioethicists have drawn on diverse methods, including qualitative interviews, focus groups, ethnographic studies, and opinion surveys advance understanding key issues bioethics. In so doing, they developed strong ties with neighboring disciplines such as anthropology, history, law, sociology. Collectively, these lines research flourished...
Abstract Recent literature has drawn attention to the complex relationship between health care and environmental crisis. Healthcare systems are significant contributors climate change degradation, crisis is making our worse thus putting more pressure on healthcare systems; environment intricately linked. In light of this relationship, we might think that there no trade‐offs environment; decision‐makers have special responsibilities values should be included in resource‐allocation decisions....
The Exception from Informed Consent (EFIC) permits patient enrolment into therapeutic emergency research where obtaining informed consent is challenging. Yet this fails to resolve a core ethical conflict in the and has generated controversy. This because existing justification practice relied on applying EFIC per study-a wholesale permission enroll irrespective of circumstance-instead patient. Our novel for centers patient, which empowers enrolling clinician judge whether patients with an...
Current guidelines do not clearly outline when assent should be attained from paediatric research participants, nor they detail the necessary elements of process. This stems fact that fundamental justification behind concept is misunderstood. In this paper, we critically assess three widespread ethical arguments used for assent: children's rights, best interests child, and respect a child's developing autonomy. We then newly-developed two-fold process: parent's pedagogical role in teaching...
Patient and public involvement (PPI) has gained widespread support in health research policy circles, but there is little consensus on the precise meaning or justifications of PPI. We argue that an important step towards clarifying justification for PPI to split apart familiar acronym draw a distinction between patient involvement. Specifically, we should refer practice involving individuals basis their experience with particular condition, while based status as members relevant population....
Both within politics and practice, the field of psychiatry is undergoing a significant transformation, as increasing emphasis placed on importance involving those with lived experience in research. In response to this participatory turn, push towards measuring impact patient involvement also growing, seeking identify how participation can improve
Research into dementia and other conditions connected with cognitive impairments is essential but conducting research populations who lack capacity to provide consent involves a number of ethical, legal practical challenges. In England Wales, family members can act as consultee or representative on behalf someone lacks capacity. However, there paucity about how make decisions concerning participation.To explore members' experiences proxy decision-making for research. Understanding are made...
Biomedical research funding bodies across Europe and North America increasingly encourage-and, in some cases, require-investigators to involve members of the public funded research. Yet there remains a striking lack clarity about what 'good' or 'successful' involvement looks like. In an effort provide guidance investigators organisations, representatives several key UK recently came together develop National Standards for Public Involvement Research. The have critical implications future...
ABSTRACT In response to increasing concerns regarding inconsistency in the decision‐making of institutional review boards (IRBs), we introduce decision‐maker's dilemma , which arises when complex, normative decisions must be made regularly. Those faced with such can either develop a process algorithmic decision‐making, consistency is ensured but many morally relevant factors are excluded from process, or embrace discretionary makes space for shape leads that inconsistent. Based on an...
When it comes to using patient data from the National Health Service (NHS) for research, we are often told that is a matter of trust: need trust, build restore trust. Various policy papers and reports articulate develop these ideas make very important contributions public dialogue on trustworthiness our research institutions. But documents policies apparently constructed with little sustained reflection nature trust trustworthiness, therefore missing features how manage concerns related We...
Population-level biomedical research offers new opportunities to improve population health, but also raises challenges traditional systems of governance and ethical oversight. Partly in response these challenges, various models public involvement are being introduced. Yet, the ways which should meet not well understood. We conducted a qualitative study with 36 experts stakeholders using World Café method identify key explore how can challenges. This brief report discusses four cross-cutting...
Abstract Data platforms represent a new paradigm for carrying out health research. In the platform model, datasets are pooled remote access and analysis, so novel insights developing better stratified and/or personalised medicine approaches can be derived from their integration. If integration of diverse enables development more accurate risk indicators, prognostic factors, or treatments interventions, this obviates need sharing reuse data; platform-based approach is an appropriate model...