A5037176103- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Pluripotent Stem Cells Research
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Mesenchymal stem cell research
- Cardiac Structural Anomalies and Repair
- Neuroscience and Neural Engineering
- Asthma and respiratory diseases
- Congenital heart defects research
- Heavy Metal Exposure and Toxicity
- Dermatology and Skin Diseases
- Toxic Organic Pollutants Impact
- Allergic Rhinitis and Sensitization
- Air Quality and Health Impacts
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
Chongqing Medical University
2025
Osaka University
2022-2024
Psoriasis risk can be affected by exposure to mixtures of environmental chemicals; however, the effect brominated flame retardants (BFRs) on self-reported psoriasis has not been assessed. Herein, we evaluated association between BFRs compounds 6 chemicals with psoriasis. Based data from National Health and Nutrition Examination Survey (NHANES) 2003-2006 2009-2014, this analysis was conducted among 6340 adults. Multivariable logistic regression, restricted cubic splines (RCS), weighted...
With the aging global population, older adult atopic dermatitis (AD) is emerging as an increasingly significant health challenge. This study aimed to evaluate burden of AD from 1990 2021 and project its change 2050. The estimates 95% uncertainty intervals prevalence, incidence, disability-adjusted life-years (DALYs) attributable among individuals aged over 60 years were extracted Global Burden Diseases (GBD) Study 2021. We used joinpoint regression analysis, decomposition cross-country...
Diabetic foot ulceration is a common chronic diabetic complication. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have been widely used in regenerative medicine owing to their multipotency and easy availability. We developed poly(lactic-co-glycolic acid) (PLGA)-based scaffold create hUC-MSC tissue sheets. In vitro immunostaining showed that sheets formed thick solid with an abundance of extracellular matrix (ECM). wounds mice treated or without either the sheet, injection,...
Abstract Background Heart failure (HF) is a major cause of death worldwide. The most effective treatment for HF heart transplantation, but its use limited by the scarcity donor hearts. Recently, stem cell-based therapy has emerged as promising approach treating myocardial infarction. Our research group been investigating human induced pluripotent cell-derived cardiomyocyte patches potential therapeutic candidate. We have successfully conducted eight cases clinical trials and demonstrated...
Abstract Human-induced pluripotent stem cell (hiPSC)-derived cardiac patches have been extensively used for treating myocardial infarction and shown potential clinical application. However, the limited patch thickness can hamper its therapeutic effect. We previously developed a fibrous scaffold that allowed formation of well-organized tissue constructs. In present study, based on above technology, we three-dimensional multilayer with dynamic perfusion, which approximately 20 million...
Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have been widely used in therapy of ischemic heart disease. However, there are still remaining issues that limit the therapeutic efficacy, such as immune rejection and low retention hiPSC-CMs. Human adipose mesenchymal stromal cells (hADSCs) reported to be able regulate response, promote angiogenesis maturation In this study, we co-cultured these two types on fiber scaffold made biodegradable poly (D,L-lactic-