A5036896466- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Manufacturing Process and Optimization
- Bone Tissue Engineering Materials
- Rocket and propulsion systems research
- Microfluidic and Bio-sensing Technologies
- Cancer Research and Treatment
- Diabetes and associated disorders
- Electron and X-Ray Spectroscopy Techniques
- Pluripotent Stem Cells Research
- Electrospun Nanofibers in Biomedical Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Pancreatic function and diabetes
- Computational Drug Discovery Methods
- Diabetes Management and Research
- Graphene and Nanomaterials Applications
- Liver physiology and pathology
- Sirtuins and Resveratrol in Medicine
- Cancer Cells and Metastasis
- Innovations in Concrete and Construction Materials
- Reconstructive Surgery and Microvascular Techniques
Novo Nordisk (Denmark)
2021
Ørsted (Denmark)
2016-2020
Technical University of Denmark
2016-2020
Abstract Encapsulation and transplantation of insulin‐producing cells offer a promising curative treatment for type 1 diabetes (T1D) without immunosuppression. However, biomaterials used to encapsulate often elicit foreign body responses, leading cellular overgrowth deposition fibrotic tissue, which in turn diminishes mass transfer from transplanted cells. Meanwhile, the encapsulation device must be safe, scalable, ideally retrievable meet clinical requirements. Here, durable safe...
Hepatic differentiation of human-induced pluripotent stem cells (hiPSCs) under flow conditions in a 3D scaffold is expected to be major step forward for construction bioartificial livers. The aims this study were induce hepatic hiPSCs perfusion and perform functional comparisons with fresh human precision-cut liver slices (hPCLS), an excellent benchmark the vivo. majority mRNA expression CYP isoenzymes transporters tested activities, Phase II metabolism, albumin, urea, bile acid synthesis...
This paper discusses experiments performed in order to validate simulations on a fused deposition modelling (FDM) extruder. The nozzle has been simulated terms of heat transfer and fluid flow. In calibrate these simulations, were giving significant look into the physical behaviour nozzle, heating cooling systems. Experiments model at different sub-mm diameters Physical parameters - especially temperature-dependent set analytical relationships receive dynamical parameters. research sets...