- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Synthesis and Characterization of Heterocyclic Compounds
- Advancements in Photolithography Techniques
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- Nanofabrication and Lithography Techniques
- Semiconductor materials and devices
- Synthesis of Tetrazole Derivatives
- Microwave-Assisted Synthesis and Applications
- Biochemical Analysis and Sensing Techniques
- Advanced Surface Polishing Techniques
- Synthesis and Reactions of Organic Compounds
- Chemical Synthesis and Reactions
- melanin and skin pigmentation
- Integrated Circuits and Semiconductor Failure Analysis
- Synthesis and Reactivity of Heterocycles
- Synthesis of heterocyclic compounds
- Quinazolinone synthesis and applications
Indian Institute of Technology Mandi
2022-2024
Dr. Babasaheb Ambedkar Marathwada University
2014-2019
An efficient synthesis of pyrazolopyranopyrimidines was achieved by four component domino reaction aldehydes, barbituric acid, hydrazine hydrate, and ethyl acetoacetate using biodegradable recyclable choline chloride:urea as deep eutectic solvent. The proceeds rapidly affords the corresponding diverse tricyclic fused with a good to excellent yield. protocol has advantage easy workup, high yields, an environmentally benign methodology compared other reported methods. simplicity this method...
Efficient and rapid synthesis of 18 tyrosinase inhibitors with good to moderate anticancer activity oral drug like properties.
Chandrakant Jadhava, Lalit D. Khillarea & Manisha R. Bhoslea*a Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India
Emergence of multidrug resistant and extensively drug tuberculosis has prompted to develop new molecular entities treat the disease. A series 4‐thiazolidinones with pyrazinyl thiazolyl scaffolds been synthesized, their antitubercular activity is reported. The title 4‐thiazolidinones, N ‐(pyrazinyl substituted thiazoloylamino)‐2‐aryl‐4‐thiazolidinones ( 6a , 6b 6c 6d 6e 6f 6g 6h 6i 6j ) have first time prepared using pyrazinamide as a starting material via five successive steps. purity...
A library of new sulfonyl decahydroacridine-1,8-diones has been efficiently synthesized by the one-pot three-component reactions 4-(p-tolyl sulfonoxy) benzaldehyde, dimedone, and amines in choline chloride-based deep eutectic mixture. Pure target compounds are obtained very good to excellent yields over short reaction times using straightforward work-up procedure. The heterocyclic were investigated for their vitro antimicrobial activity. minimum inhibitory concentration was determined test...
Given the need for advanced resist materials in view of fast shrinkage semiconductor node scaling, this work demonstrates lithography application an organotin-based cyclotrimeric species (Sn–CT) as a molecular sub-10 nm patterning using electron beam (EBL) and helium ion (HIBL) techniques. While has been successfully used ∼15 line/space features ∼9 discrete line at dose 2.5 mC/cm2 EBL, were printed on silicon 16 μC/cm2 HIBL. Moreover, Sn–CT also complex single nanometer regime such...
A simple and efficient protocol developed for the synthesis of 5-substituted 1H-tetrazole derivatives through [2+3] cycloaddition reaction between benzonitriles sodium azide using diisopropylethylammonium acetate as a recyclable medium is described. The reactions proceed well at 80 °C provide corresponding tetrazoles in good to excellent yields (up 94% yield). Developed method has notable advantages, such mild conditions, easy workup, reusability with consistent catalytic activity, safer...
Inorganic resists have emerged as promising candidates in semiconductor industries to realize sub-10 nm node technology. However, controlling vertical shrinkage of resist films during the pattern development process, particularly for ultralow thin film applications, is among highly pressing limitations inorganic along with roughness and poor shelf-life characteristics. Tin-based clusters small molecules been recently introduced materials. They possess a high absorption coefficient fast...
Background: Thiazolidinone and pyrazoles are promising heterocyclic systems enormously contributing to medicinal chemistry when pyrazole nucleus was incorporated in other biodynamic heterocycles, the resulting molecules have displayed an increased spectrum of biological activities. There several synthetic routes for synthesis thiazolidinone but having certain lacunas like, need catalysts desiccants, higher reaction temperature, longer time, organic solvents tedious work up procedure....
While inorganic resists are emerging as possible potential candidates for sub-10 nm node semiconductor fabrication, fundamental understanding on such promising chemical compositions is inevitably paramount to confront the concerning challenges associated with resists. Given that assisted nanopatterning of may significantly improve patterning capability along addressing vertical shrinkage issue resist film during processing and a greater extent, we present an interesting aspect matrix...
2, 4-Thiazolidinedione (TZD), pyrazole and thiazole heterocyclic rings exhibit a wide range of pharmacological activities. Medicinal chemists use these moieties as scaffolds in drug designing discovery. The existing medicaments, celecoxib meloxicam, used for treating inflammation pain are having, thiazole, respectively key scaffolds. Pyrazoles coupled with 4-thiazolidinediones may display enhanced anti-inflammatory activity. With this hope the bench work was carried out.Heterocyclic...
Abstract The environmentally friendly ultrasound promoted method offers several advantages such as operational simplicity, easy work‐up procedure, shorter reaction times, and high yields.
Abstract A one‐pot four‐component cyclocondensation of aromatic aldehydes, malononitrile, ethyl acetoacetate, and hydrazine hydrate affords the title products in high yields within 20 minutes.