A5023435916- Acute Kidney Injury Research
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Transplantation: Methods and Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Renal function and acid-base balance
- Renal Transplantation Outcomes and Treatments
- Pharmacological Effects and Toxicity Studies
- Poisoning and overdose treatments
- Central Venous Catheters and Hemodialysis
- Blood Pressure and Hypertension Studies
- Organ Transplantation Techniques and Outcomes
- Muscle and Compartmental Disorders
- Renal and related cancers
- Neonatal Health and Biochemistry
- Health Systems, Economic Evaluations, Quality of Life
- Renal Diseases and Glomerulopathies
- Neonatal Respiratory Health Research
- Electrolyte and hormonal disorders
- Trauma and Emergency Care Studies
- Autopsy Techniques and Outcomes
University of Calgary
2025
Stanford University
2015-2024
Lucile Packard Children's Hospital
2011-2023
Palo Alto University
2008-2023
Stanford Medicine
2009-2022
Planned Parenthood
2022
Stanford Health Care
2016-2022
Nationwide Children's Hospital
2021
The Ohio State University
2021
Broad Institute
2018
Background and objectives Although several standardized definitions for AKI have been developed, no consensus exists regarding which to use in children. This study applied the Pediatric RIFLE (pRIFLE), Network (AKIN), Kidney Disease Improving Global Outcomes (KDIGO) criteria an anonymized cohort of hospitalizations extracted from electronic medical record compare incidence outcomes intensive care unit (ICU) non-ICU pediatric populations. Design, setting, participants, & measurements...
Summary Background and objectives Although AKI is common among hospitalized children, comprehensive epidemiologic data are lacking. This study characterizes pediatric across the United States identifies risk factors using high-content/high-throughput analytic techniques. Design, setting, participants, & measurements For cross-sectional analysis of 2009 Kids Inpatient Database, events were identified International Classification Diseases, Ninth Revision, Clinical Modification codes....
Importance Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults is associated with poor short-term long-term outcomes. Guidance required to focus efforts related expansion of pediatric AKI knowledge. Objective To develop expert-driven specific recommendations on needed research, education, practice, advocacy. Evidence Review At the 26th Acute Disease Quality Initiative meeting conducted November 2021 by 47 multiprofessional international...
Pediatricians facing critical clinical decisions often lack data on which to draw. The authors recently put their institution's electronic medical record unusual use inform a decision about anticoagulation in patient with systemic lupus erythematosus.
Sutherland SM, Chen G, Sequeira FA, Lou CD, Alexander SR, Tyan DB. Complement‐fixing donor‐specific antibodies identified by a novel C1q assay are associated with allograft loss. Pediatr Transplantation 2012: 16: 12–17. © 2011 John Wiley & Sons A/S. Abstract: Long‐term outcomes following renal transplantation remain disappointing. Recently, interest has focused on the antibody‐mediated component of injury and deleterious effects DSA. We applied solid‐phase in parallel standard IgG SAB to...
OBJECTIVES: With the recognition that fluid overload (FO) has a detrimental impact on critically ill children, critical care nephrology community focused identifying clinically meaningful targets for intervention. The current study aims to evaluate epidemiology and outcomes associated with FO in an international multicenter cohort of children. also association at predetermined relevant thresholds time points (FO ≥ 5% 10% end ICU days 1 2) outcomes. DESIGN: Prospective study. SETTING:...
Hypertension occurs in 2% to 5% of children the United States, and its prevalence has increased during obesity epidemic. There is no consensus among professional organizations about how frequently blood pressure should be measured >3 years old. The purpose this study was estimate frequency hypertension screening ambulatory pediatric visits States determine patient- provider-level factors associated with specifically for preventive care.We analyzed data from a nationally representative sample...
Objectives: Acute kidney injury occurs commonly in children following congenital cardiac surgery with cardiopulmonary bypass and has been associated increased morbidity mortality. Aminophylline, a methylxanthine nonselective adenosine receptor antagonist, effective the management of acute certain populations. This study sought to determine whether postoperative administration aminophylline attenuates undergoing bypass. Design: Single-center, double-blinded, placebo-controlled, randomized...
Consensus definitions for acute kidney injury are based on changes in serum creatinine and urine output. Although the criteria have been widely applied, contribution of output remains poorly understood. We evaluated these individually collectively to determine their impact diagnosis outcome severe injury.Post hoc analysis Assessment Worldwide Acute Kidney Injury, Renal Angina, Epidemiology study-a prospective international observational multicenter study.Critically ill children enrolled...
Pre- or postdialysis BP recordings are imprecise, can be biased, and have poor test-retest reliability in children on dialysis. We aimed to examine the possible differences between pre- levels 24-hour ambulatory monitoring (ABPM) diagnosis of hypertension (HTN).Twenty-four dialysis had ABPM interdialytic period, values were compared with average systolic (SBP) diastolic (DBP) that week. Each patient an echocardiogram determine presence left ventricular hypertrophy (LVH).By ABPM, 8% patients...
Objectives: Recent data have suggested an association between the use of dexmedetomidine and a decreased incidence acute kidney injury in adult patients after cardiopulmonary bypass. However, no study has focused on this among pediatric populations where is particularly high critical significance. The primary objective was to assess relationship postoperative undergoing secondary determine whether there duration mechanical ventilation or cardiovascular ICU stay. Design: Single-center...