A5102927999- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Central Venous Catheters and Hemodialysis
- Organ Donation and Transplantation
- Acute Kidney Injury Research
- Organ Transplantation Techniques and Outcomes
- Renal Diseases and Glomerulopathies
- Pregnancy and Medication Impact
- Neonatal Health and Biochemistry
- Muscle and Compartmental Disorders
- Pediatric Urology and Nephrology Studies
- Complement system in diseases
- Renal function and acid-base balance
- Pharmacological Effects and Toxicity Studies
- Metabolism and Genetic Disorders
- Adolescent and Pediatric Healthcare
- Iron Metabolism and Disorders
- Renal and Vascular Pathologies
- Electrolyte and hormonal disorders
- Childhood Cancer Survivors' Quality of Life
- Erythropoietin and Anemia Treatment
- Cytomegalovirus and herpesvirus research
- Hemodynamic Monitoring and Therapy
- Ethics and Legal Issues in Pediatric Healthcare
- Urological Disorders and Treatments
Spark Therapeutics (United States)
2025
The University of Texas at Austin
2023-2024
The University of Melbourne
2023
Louisiana State University Health Sciences Center Shreveport
2022
Lucile Packard Children's Hospital
2005-2021
Stanford University
2009-2021
Park Nicollet Methodist Hospital
2021
Royal Hospital for Children
2015
University of the Pacific
2013
Stanford Medicine
1998-2012
Summary Background and objectives Although AKI is common among hospitalized children, comprehensive epidemiologic data are lacking. This study characterizes pediatric across the United States identifies risk factors using high-content/high-throughput analytic techniques. Design, setting, participants, & measurements For cross-sectional analysis of 2009 Kids Inpatient Database, events were identified International Classification Diseases, Ninth Revision, Clinical Modification codes....
Objective To compare outcomes from pediatric intensive care in hospitals with different levels of resources. Design Prospective, blinded comparison outcome and Setting Tertiary (n = 3) nontertiary 71) Oregon southwestern Washington. Patients All critically ill children admitted respiratory failure head trauma for 6 months. Measurements Main Results Severity illness adjusted mortality rates were determined using admission day, physiologic profiles (Pediatric Risk Mortality score) modalities...
This article reports demographic characteristics and intensive care unit survival for 344 patients from the Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) Registry, a voluntary multicenter observational network.Ages were newborn to 25 yr, 58% male, weights 1.3 160 kg. Patients spent median of 2 d in before CRRT (range 0 135). At initiation, 48% received diuretics 66% vasoactive drugs. Mean blood flow was 97.9 ml/min 10 350 ml/min; 100 ml/min); mean per body weight 5 kg...
The peritoneal catheter is the PD patient's lifeline. Advances in knowledge have made it possible to obtain access cavity safely and maintain over an extended period of time. Catheter-related infections remain a major problem, solutions for which are being actively researched. Nevertheless, successful outcome very much dependent on meticulous care attention detail. Adherence principles insertion subsequent management cornerstone access. guidelines provided this publication represent...
THE American Society of Transplant Physicians directed its Patient Care and Education Committee to examine the issue racial inequality in transplantation. The committee, made up physicians involved clinical transplantation, used both published data personal experience develop a consensus on issues problems related race This report summarizes conclusions reached by committee outlines specific recommendations society. Prevalence Incidence End-Stage Renal Disease among Minorities To kidney it...
Background. Corticosteroids have been invariant transplant immunosuppressives with numerous adverse effects. We previously reported 6-month results in 10 patients using extended daclizumab induction to safely eliminate steroid use pediatric renal transplantation. This expanded pilot series discusses immunosuppression dosing modification further minimize drug toxicity without sacrificing regimen efficacy. Methods. Fifty-seven recipients were enrolled the steroid-free protocol. Extended...
The recommendations provided in this document represent a distillation of various experiences, as well data obtained from published studies the setting substantial changes antibiotic sensitivity. It is hoped that revised compilation will provide basis upon which future developments and advances can be made therapeutic approach to infectious complications peritoneal dialysis.
Data from the North American Pediatric Renal Transplant Cooperative Study were analyzed to determine incidence and possible causes of graft thrombosis in pediatric renal transplant recipients. Between January 1987, November 1989, 1045 transplants recipients <18 years age registered study, including 484 living-related donor 561 cadaver transplants. There 213 failures (67 LRD, 146 CAD), these 27 caused by (8 19 CAD). Thrombosis occurred 2.6% all accounted for 22.5% (27/120) that first 60 days...
Sutherland SM, Chen G, Sequeira FA, Lou CD, Alexander SR, Tyan DB. Complement‐fixing donor‐specific antibodies identified by a novel C1q assay are associated with allograft loss. Pediatr Transplantation 2012: 16: 12–17. © 2011 John Wiley & Sons A/S. Abstract: Long‐term outcomes following renal transplantation remain disappointing. Recently, interest has focused on the antibody‐mediated component of injury and deleterious effects DSA. We applied solid‐phase in parallel standard IgG SAB to...
The criteria for acceptance of candidates renal transplantation varies throughout the United States. Patient Care and Education Committee American Society Transplant Physicians conducted a survey all U.S. centers that participate in Network Organ Sharing (UNOS) concerning their evaluation adult kidney transplantation. response to each question was examined according specialty individual who filled out questionnaire, as well type transplant center (university or private) size center. rate 81%...
Post-transplant anemia (PTA), a frequent complication during the first 3-6 months after transplant, is thought to be uncommon late post-transplant period. A study population of adults (> 18 years) transplanted 1995 at Stanford University (n = 88) and North Carolina 40) was selected. Data-collection points were 0, 1, 2, 3, 4 5 years post transplant. Anemia defined as hematocrit < 33 volume percentage. Thirty percent patients anemic some time The prevalence PTA increased over time; by 26%...
Background. Nationally, results of renal transplantation in infants are inferior to those older children and adults. Within the infant group, best obtained with adult-sized kidneys (ASKs) rather than size-compatible pediatric kidneys. However, ASKs into has an increased risk acute tubular necrosis graft loss from vascular thrombosis primary nonfunction. The aim this study was define understand hemodynamic changes induced by ASK transplantation, so that outcomes can be improved. Methods. Nine...
Purpose Well-functioning vascular access is essential for the provision of adequate CRRT However, few data exist to describe effect catheter size or location on performance in pediatric population. Methods Data site, size, and location, as well type anticoagulant used patient demographic were gathered from ppCRRT registry. Kaplan-Meier curves generated then analyzed by log-rank test Cox Proportional Hazards model. Results Access diameter was found significantly affect circuit survival. None...
To identify predictors of wait-listing for kidney transplantation, and mortality among children with lupus nephritis-associated end-stage renal disease (ESRD).Children ages 5-18 years new-onset ESRD were identified in the US Renal Data System (1995-2006). Demographic clinical characteristics, causes death, during first 5 investigated. Cox proportional hazards models used.A total 583 had incident ESRD. The mean ± SD age patients at time onset was 16.2 2.4 years; 49% African American, 24%...
Data from the North American Pediatric Renal Transplant Cooperative Study were analyzed to determine effect of donor age on graft survival for pediatric recipients cadaver renal transplants. Between January 1, 1987, and November 16, 1990, 787 transplants in children <18 years registered study. The ages donors ≤5 203 transplants, between 6 9 87, 10 39 389, ≥40 108. risk loss was related by a proportional hazards analysis. ideal 20–25 years. increased both young old age. neonate 2.7-fold that...