Stephen M. Gorga
A5050842521- Acute Kidney Injury Research
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Renal function and acid-base balance
- Hemodynamic Monitoring and Therapy
- Central Venous Catheters and Hemodialysis
- Neonatal Respiratory Health Research
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Family and Patient Care in Intensive Care Units
- Trauma and Emergency Care Studies
- Scheduling and Timetabling Solutions
- Healthcare Operations and Scheduling Optimization
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical Reasoning and Diagnostic Skills
- Metabolism and Genetic Disorders
- Kawasaki Disease and Coronary Complications
- Pediatric Pain Management Techniques
- Enhanced Recovery After Surgery
- Patient Safety and Medication Errors
- Adolescent and Pediatric Healthcare
University of Michigan
2017-2025
C. S. Mott Children's Hospital
2017-2025
Michigan Medicine
2020-2024
Michigan United
2022-2023
Baylor College of Medicine
2023
Cincinnati Children's Hospital Medical Center
2023
Lurie Children's Hospital
2023
Northwestern University
2023
Importance Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults is associated with poor short-term long-term outcomes. Guidance required to focus efforts related expansion of pediatric AKI knowledge. Objective To develop expert-driven specific recommendations on needed research, education, practice, advocacy. Evidence Review At the 26th Acute Disease Quality Initiative meeting conducted November 2021 by 47 multiprofessional international...
OBJECTIVES: With the recognition that fluid overload (FO) has a detrimental impact on critically ill children, critical care nephrology community focused identifying clinically meaningful targets for intervention. The current study aims to evaluate epidemiology and outcomes associated with FO in an international multicenter cohort of children. also association at predetermined relevant thresholds time points (FO ≥ 5% 10% end ICU days 1 2) outcomes. DESIGN: Prospective study. SETTING:...
Importance Continuous kidney replacement therapy (CKRT) is increasingly used in youths with critical illness, but little known about longer-term outcomes, such as persistent dysfunction, continued need for dialysis, or death. Objective To characterize the incidence and risk factors, including liberation patterns, associated major adverse events 90 days after CKRT initiation (MAKE-90) children, adolescents, young adults. Design, Setting, Participants This international, multicenter cohort...
Continuous renal replacement therapy (CRRT) is used for the symptomatic management of acute kidney injury (AKI) and fluid overload (FO). Contemporary reports on pediatric CRRT are small single center in design. Large international studies evaluating practice outcomes lacking. Herein, we describe design a multinational collaborative.
Importance Kidney disease is common in infants admitted to the neonatal intensive care unit (NICU). Despite risk of chronic kidney (CKD) discharged from NICU, neither evidence- nor expert-based recommendations exist guide clinical after discharge. Objective To develop for stratification and health monitoring among discharge NICU. Evidence Review At National Institute Health–supported Consensus Workshop Address Health Neonatal Intensive Care Unit Graduates meeting conducted February 2024, a...
In clinical trials, the early or accelerated continuous renal replacement therapy (CRRT) initiation strategy among adults with acute kidney injury volume overload has not demonstrated a survival benefit. Whether timing of CRRT is associated outcomes children and young unknown.
<title>Abstract</title> How does a physician decide to use recently FDA-approved life-saving device in desperately ill child which little prior clinical experience is available? This report presents pediatric patient with neutropenic septic shock and multiorgan failure (MOF) 95% chance of death the availability therapeutic completely new approach treat sepsis. device, called selective cytopheretic (SCD), first-in-class autologous immune cell directed therapy. The SCD, when integrated into an...
Prior criteria for organ dysfunction in critically ill children were based mainly on expert opinion. We convened the Pediatric Organ Dysfunction Information Update Mandate (PODIUM) panel to summarize data characterizing single and multiple derive contemporary pediatric dysfunction. The was composed of 88 members representing 47 institutions 7 countries. conducted systematic reviews literature evidence-based neurologic, cardiovascular, respiratory, gastrointestinal, acute liver, renal,...
Effective interventions to prevent diagnostic error among critically ill children should be informed by prevalence and etiologies. We aimed determine the characteristics of errors identify factors associated with in patients admitted PICU.
Acute kidney injury (AKI) in children is associated with increased morbidity, reduced health-related quality of life, greater resource utilization, and higher mortality. Improvements the timeliness precision AKI diagnosis are needed. In this report, we highlight existing, novel, on-the-horizon diagnostic risk-stratification tools for pediatric AKI, outline opportunities integration into clinical practice. We also summarize pediatric-specific high-risk diagnoses exposures as well potential...
Two infants with disseminated adenoviral infections are described. Both these had a similar clinical course and were also diagnosed secondary hemophagocytic lymphohistiocytosis (HLH). Previous reports of immunocompromised adults adenovirus-associated HLH in the literature; however, this is first report that we aware pathology occurring infants. These cases used to demonstrate importance thinking about patients who adenovirus exhibit prolonged fevers unresponsive antimicrobial agents...