A5014645656- Gestational Diabetes Research and Management
- Bariatric Surgery and Outcomes
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Obesity, Physical Activity, Diet
- Obesity and Health Practices
- Mobile Health and mHealth Applications
- Diabetes Management and Education
- Nutritional Studies and Diet
- Diet and metabolism studies
- Cardiovascular Disease and Adiposity
- Diabetes Management and Research
- Fatty Acid Research and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cholesterol and Lipid Metabolism
- Cardiovascular Health and Disease Prevention
- Peroxisome Proliferator-Activated Receptors
- Innovative Human-Technology Interaction
- Cardiovascular Function and Risk Factors
- Vitamin D Research Studies
- Oral microbiology and periodontitis research
- Diabetes and associated disorders
- HIV/AIDS oral health manifestations
- Physical Activity and Health
University of Helsinki
2016-2025
Helsinki University Hospital
2016-2025
Turku University Hospital
2022-2023
University of Turku
2022-2023
Kätilöopisto Maternity Hospital
2015-2017
South Karelia Central Hospital
2015-2016
Jorvi Hospital
2016
OBJECTIVE To assess whether gestational diabetes mellitus (GDM) can be prevented by a moderate lifestyle intervention in pregnant women who are at high risk for the disease. RESEARCH DESIGN AND METHODS Two hundred ninety-three with history of GDM and/or prepregnancy BMI ≥30 kg/m2 were enrolled study <20 weeks gestation and randomly allocated to group (n = 155) or control 138). Each subject received individualized counseling on diet, physical activity, weight from trained nurses, had...
Maternal overweight, obesity and consequently the incidence of gestational diabetes are increasing rapidly worldwide. The objective study was to assess efficacy cost-effectiveness a combined diet physical activity intervention implemented before, during after pregnancy in primary health care setting for preventing diabetes, later type 2 other metabolic consequences.RADIEL is randomized controlled multi-center trial women at high risk (a previous history or prepregnancy BMI ≥30 kg/m2)....
Abstract Introduction An altered gut microbiome composition is shown to be associated with various diseases and health outcomes. We compare the microbiota of women who developed gestational diabetes mellitus ( GDM ) that those did not, their offspring, determine any differences in diversity microbiota, which may correlated state. Material methods All were at high risk for participated Finnish Gestational Diabetes Prevention Study RADIEL ). Stool samples obtained, 5 years postpartum, from 60...
Gestational Diabetes Mellitus (GDM) prevalence is rising worldwide, but optimal dietary strategies remain unclear. The eMOM pilot RCT compared a plant-protein rich Healthy Nordic Diet (HND) and moderately carbohydrate restricted diet (MCRD) their potential effects on time in glucose target range (≤ 7.8 mmol/L, %TIR), newborn body composition. Forty-two participants were randomized to either HND (n = 20) or MCRD 22) face-to-face nutritional counseling from gestational weeks (GW) 24 + 0-28 6...
Comprehensive assessment of metabolism in maternal obesity and pregnancy disorders can provide information about the shared maternal-fetal milieu give insight into both long-term health intergenerational transmission disease burden.
Abstract Background Overweight and obesity are well‐known risk factors for several pregnancy‐related complications, but the nature of association between maternal adiposity these complications has been less studied. The objective present study was to examine shape magnitude prepregnancy body mass index gestational diabetes, pre‐eclampsia different severity, hypertension, obstetric cholestasis among F innish primiparae women. Methods Data on all women who delivered a singleton newborn in...
Lifestyle intervention studies performed during pregnancy have shown inconsistent results in relation to prevention of gestational diabetes mellitus (GDM). Therefore, the aim this study was assess effect an initiated already before GDM high-risk women.A randomized controlled trial conducted four Finnish maternity hospitals between years 2008 and 2014. Altogether 228 women planning were (n=116) or a control group (n=112). The risk factors body mass index ≥30 kg/m2 (n=46), prior (n=120), both...
Women with a history of gestational diabetes (GDM) have sevenfold risk developing type 2 diabetes. To assess the effects lifestyle intervention during pregnancy and first postpartum year on glucose regulation, weight retention, metabolic characteristics among women at high GDM risk. In Finnish Gestational Diabetes Prevention study, trained study nurses provided counseling in each trimester 6 weeks, months, 12 months postpartum. Three maternity hospitals Helsinki area one Lappeenranta. total,...
The aim was to develop and validate a food-based diet quality index for measuring adherence the Nordic Nutrition Recommendations (NNR) in pregnant population with high risk of gestational diabetes (GDM). This study is part Finnish Gestational Diabetes Prevention Study (RADIEL), lifestyle intervention conducted between 2008 2014. 443 participants (61 % those invited), were either obese or had history GDM. Food frequency questionnaires collected at 1st trimester served composing HFII; sum 11...
Gestational diabetes (GDM) has considerable and increasing health effects as it raises both the mother's offspring's risk for short- long-term problems. GDM can usually be treated with a healthier lifestyle, such appropriate dietary modifications sufficient physical activity. Although telemedicine interventions providing weekly or more frequent feedback from care professionals have shown potential to improve glycemic control among women GDM, apps without extensive input are limited not been...
In non-pregnant population, nonobese individuals with obesity-related metabolome have increased risk for type 2 diabetes and cardiovascular diseases. The of these diseases is also after gestational diabetes.This work aimed to examine whether (body mass index [BMI] < 30) obese (BMI ≥ women mellitus (GDM) non-GDM differ in metabolomic profiles from controls.Levels 66 metabolic measures were assessed early (median 13, IQR 12.4-13.7 gestation weeks), across early, mid (20, 19.3-23.0), late (28,...
The prevalence of gestational diabetes (GDM) has been increasing along with the obesity pandemic. It is associated pregnancy complications and a risk type 2 diabetes.To study nutrient intake among pregnant Finnish women at increased GDM due to or history GDM.Food records from obese (n=394) were examined baseline (≤20 weeks pregnancy) Gestational Diabetes Prevention Study.The had mean fat 33 en% (SD 7), saturated fatty acids (SFA) 12 3), carbohydrate 46 6). Sucrose was 7 which different other...
Objective To study the incidence of gestational diabetes mellitus (GDM) in relation to phenotypic characteristics and weight gain (GWG) among women at high risk for GDM.
To compare and select machine learning models, relying on performance measures alone may not always be sufficient. This is particularly the case where different subsets, features, predicted results vary in importance relative to task at hand. Explanation visualization techniques are required support model sensemaking informed decision-making. However, a review shows that existing systems mostly designed for developers evaluated with target users their effectiveness. address this issue,...
Introduction Lifestyle interventions are effective in preventing type 2 diabetes, but genetic background may influence the individual response. In Finnish gestational diabetes prevention study, RADIEL, lifestyle intervention during pregnancy and first postpartum year was (GDM) glycemic abnormalities only among women at highest risk of diabetes. This study aimed to assess whether still 5 years modifies association between health. Research design methods The RADIEL (randomized controlled...
The global prevalence of obesity in women keeps increasing. preconception period may be a window opportunity to improve lifestyle, reduce and cardiometabolic health. This study assessed the effect lifestyle intervention on long-term health two randomized controlled trials (RCTs). Participants LIFEstyle RADIEL studies with baseline body mass index (BMI) ≥29 kg/m2 were eligible for this follow-up study. Both between targeting physical activity, diet behaviour modification or usual care. We 6...
Only little information is available on health-related quality of life (HRQoL) and its changes during the course a normal pregnancy. We studied in HRQoL pregnant population pregnancy until 1 year postpartum different body mass index (BMI) groups.Seven hundred fifty women attending first ultrasound examination before gestational week 14 were invited to participate longitudinal, communal-based survey. The participants divided into three groups according their BMI; <25, 25-29.9, ≥30 kg/m2 ....
Gestational diabetes mellitus (GDM) has considerable and increasing health effects as it raises both the mother's offspring's risk for short- long-term problems. GDM can usually be treated with a healthier lifestyle, such appropriate dietary modifications engaging insufficient physical activity. While telemedicine interventions requiring weekly or more frequent feedback from care professionals have shown potential to improve glycemic control amongst women GDM, apps without extensive input...
Introduction Gestational diabetes (GDM) causes various adverse short-term and long-term consequences for the mother child, its incidence is increasing globally. So far, most promising digital health interventions GDM management have involved healthcare professionals to provide guidance feedback. The principal aim of this study evaluate effects comprehensive real-time self-tracking with eMOM mobile application (app) on glucose levels in women GDM, more broadly, different other maternal...